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| Transduction of receptor signals by β-arrestins RJ Lefkowitz, SK Shenoy science 308 (5721), 512-517, 2005 | 2174 | 2005 |
| A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor. A De Lean, JM Stadel, RJ Lefkowitz Journal of Biological Chemistry 255 (15), 7108-7117, 1980 | 2124 | 1980 |
| β-Arrestin-dependent formation of β2 adrenergic receptor-Src protein kinase complexes LM Luttrell, S Ferguson, Y Daaka, WE Miller, S Maudsley, GJ Della Rocca, ... Science 283 (5402), 655-661, 1999 | 1910 | 1999 |
| Model systems for the study of seven-transmembrane-segment receptors HG Dohlman, J Thorner, MG Caron, RJ Lefkowitz Annual review of biochemistry 60 (1), 653-688, 1991 | 1885 | 1991 |
| Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin RAF Dixon, BK Kobilka, DJ Strader, JL Benovic, HG Dohlman, T Frielle, ... Nature 321 (6065), 75-79, 1986 | 1767 | 1986 |
| β-arrestins and cell signaling SM DeWire, S Ahn, RJ Lefkowitz, SK Shenoy Annu. Rev. Physiol. 69 (1), 483-510, 2007 | 1757 | 2007 |
| Turning off the signal: desensitization of β‐adrenergic receptor function WP Hausdorff, MG Caron, RJ Lefkowitz The FASEB Journal 4 (11), 2881-2889, 1990 | 1722 | 1990 |
| Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A Y Daaka, LM Luttrell, RJ Lefkowitz Nature 390 (6655), 88-91, 1997 | 1683 | 1997 |
| Intemational union of pharmacology nomenclature of adrenoceptors B Db Pharmacol Rev 46, 121-136, 1994 | 1672 | 1994 |
| G protein–coupled receptor kinases JA Pitcher, NJ Freedman, RJ Lefkowitz Annual review of biochemistry 67 (1), 653-692, 1998 | 1663 | 1998 |
| A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model. P Samama, S Cotecchia, T Costa, RJ Lefkowitz Journal of Biological Chemistry 268 (7), 4625-4636, 1993 | 1629 | 1993 |
| β-Arrestin: a protein that regulates β-adrenergic receptor function MJ Lohse, JL Benovic, J Codina, MG Caron, RJ Lefkowitz Science 248 (4962), 1547-1550, 1990 | 1582 | 1990 |
| The role of β-arrestins in the termination and transduction of G-protein-coupled receptor signals LM Luttrell, RJ Lefkowitz Journal of cell science 115 (3), 455-465, 2002 | 1544 | 2002 |
| G protein-coupled receptors: III. New roles for receptor kinases and β-arrestins in receptor signaling and desensitization RJ Lefkowitz Journal of Biological Chemistry 273 (30), 18677-18680, 1998 | 1445 | 1998 |
| Seven-transmembrane-spanning receptors and heart function HA Rockman, WJ Koch, RJ Lefkowitz Nature 415 (6868), 206-212, 2002 | 1341 | 2002 |
| Enhanced morphine analgesia in mice lacking β-arrestin 2 LM Bohn, RJ Lefkowitz, RR Gainetdinov, K Peppel, MG Caron, FT Lin Science 286 (5449), 2495-2498, 1999 | 1272 | 1999 |
| An Akt/β-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior JM Beaulieu, TD Sotnikova, S Marion, RJ Lefkowitz, RR Gainetdinov, ... Cell 122 (2), 261-273, 2005 | 1186 | 2005 |
| μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence LM Bohn, RR Gainetdinov, FT Lin, RJ Lefkowitz, MG Caron Nature 408 (6813), 720-723, 2000 | 1143 | 2000 |
| Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds LM Luttrell, FL Roudabush, EW Choy, WE Miller, ME Field, KL Pierce, ... Proceedings of the National Academy of Sciences 98 (5), 2449-2454, 2001 | 1076 | 2001 |
Jeffrey BenovicThomas Eakins Professor of Biochemistry and Molecular Biology, Thomas Jefferson UniversityE-mail confirmado em jefferson.edu
