Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ... Nature 482 (7384), 226-231, 2012 | 2826 | 2012 |
DNA methylation-based classification of central nervous system tumours D Capper, DTW Jones, M Sill, V Hovestadt, D Schrimpf, D Sturm, ... Nature 555 (7697), 469-474, 2018 | 2646 | 2018 |
Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ... Cancer cell 22 (4), 425-437, 2012 | 2069 | 2012 |
The landscape of genomic alterations across childhood cancers SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ... Nature 555 (7696), 321-327, 2018 | 1510 | 2018 |
Molecular classification of ependymal tumors across all CNS compartments, histopathological grades, and age groups KW Pajtler, H Witt, M Sill, DTW Jones, V Hovestadt, F Kratochwil, K Wani, ... Cancer cell 27 (5), 728-743, 2015 | 1195 | 2015 |
A perfect message: RNA surveillance and nonsense-mediated decay MW Hentze, AE Kulozik Cell 96 (3), 307-310, 1999 | 1051 | 1999 |
Dissecting the genomic complexity underlying medulloblastoma DTW Jones, N Jäger, M Kool, T Zichner, B Hutter, M Sultan, YJ Cho, ... Nature 488 (7409), 100-105, 2012 | 980 | 2012 |
Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations T Rausch, DTW Jones, M Zapatka, AM Stütz, T Zichner, J Weischenfeldt, ... Cell 148 (1), 59-71, 2012 | 979 | 2012 |
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma DTW Jones, B Hutter, N Jäger, A Korshunov, M Kool, HJ Warnatz, ... Nature genetics 45 (8), 927-932, 2013 | 855 | 2013 |
Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition M Kool, DTW Jones, N Jäger, PA Northcott, TJ Pugh, V Hovestadt, ... Cancer cell 25 (3), 393-405, 2014 | 847 | 2014 |
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma PA Northcott, C Lee, T Zichner, AM Stütz, S Erkek, D Kawauchi, DJH Shih, ... Nature 511 (7510), 428-434, 2014 | 742 | 2014 |
Nonsense-mediated decay approaches the clinic JA Holbrook, G Neu-Yilik, MW Hentze, AE Kulozik Nature genetics 36 (8), 801-808, 2004 | 735 | 2004 |
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ... Nature 506 (7489), 445-450, 2014 | 669 | 2014 |
A sensitive array for microRNA expression profiling (miChip) based on locked nucleic acids (LNA) M Castoldi, S Schmidt, V Benes, M Noerholm, AE Kulozik, MW Hentze, ... Rna 12 (5), 913-920, 2006 | 602 | 2006 |
BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas S Pfister, WG Janzarik, M Remke, A Ernst, W Werft, N Becker, G Toedt, ... The Journal of clinical investigation 118 (5), 1739-1749, 2008 | 601 | 2008 |
Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma H Witt, SC Mack, M Ryzhova, S Bender, M Sill, R Isserlin, A Benner, ... Cancer cell 20 (2), 143-157, 2011 | 583 | 2011 |
Atypical teratoid/rhabdoid tumors are comprised of three epigenetic subgroups with distinct enhancer landscapes PD Johann, S Erkek, M Zapatka, K Kerl, I Buchhalter, V Hovestadt, ... Cancer cell 29 (3), 379-393, 2016 | 559 | 2016 |
Binary specification of nonsense codons by splicing and cytoplasmic translation R Thermann, G Neu‐Yilik, A Deters, U Frede, K Wehr, C Hagemeier, ... The EMBO journal, 1998 | 501 | 1998 |
Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias C Shochat, N Tal, OR Bandapalli, C Palmi, I Ganmore, G te Kronnie, ... Journal of Experimental Medicine 208 (5), 901-908, 2011 | 432 | 2011 |
Sarcoma classification by DNA methylation profiling C Koelsche, D Schrimpf, D Stichel, M Sill, F Sahm, DE Reuss, M Blattner, ... Nature communications 12 (1), 498, 2021 | 407 | 2021 |