Artigos com autorizações de acesso público - Jinbin XuSaiba mais
2 artigos não disponíveis publicamente
γ-Secretase activity, clinical features, and biomarkers of autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analysis of the Dominantly Inherited …
SA Schultz, L Liu, AP Schultz, CD Fitzpatrick, R Levin, JP Bellier, ...
The Lancet Neurology 23 (9), 913-924, 2024
Autorizações: Michael J Fox Foundation
Longitudinal analysis of a dominantly inherited Alzheimer disease mutation carrier protected from dementia
JJ Llibre-Guerra, MV Fernandez, N Joseph-Mathurin, S Bian, K Carter, ...
Nature Medicine, 1-9, 2025
Autorizações: Fonds de recherche du Québec - Santé
83 artigos disponíveis publicamente
Epigenetic priming of memory updating during reconsolidation to attenuate remote fear memories
J Gräff, NF Joseph, ME Horn, A Samiei, J Meng, J Seo, D Rei, AW Bero, ...
Cell 156 (1), 261-276, 2014
Autorizações: US National Institutes of Health, Howard Hughes Medical Institute
Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site
J Xu, C Zeng, W Chu, F Pan, JM Rothfuss, F Zhang, Z Tu, D Zhou, D Zeng, ...
Nature communications 2 (1), 380, 2011
Autorizações: US National Institutes of Health
Alzheimer's therapeutics targeting amyloid beta 1–42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity
NJ Izzo, J Xu, C Zeng, MJ Kirk, K Mozzoni, C Silky, C Rehak, R Yurko, ...
PloS one 9 (11), e111899, 2014
Autorizações: US National Institutes of Health
Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid
A Drieu, S Du, SE Storck, J Rustenhoven, Z Papadopoulos, T Dykstra, ...
Nature 611 (7936), 585-593, 2022
Autorizações: US National Institutes of Health, Federal Ministry of Education and Research …
Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study
E Morenas-Rodríguez, Y Li, B Nuscher, N Franzmeier, C Xiong, ...
The Lancet Neurology 21 (4), 329-341, 2022
Autorizações: US National Institutes of Health, German Research Foundation, Swedish …
Binding of the radioligand SIL23 to α-synuclein fibrils in Parkinson disease brain tissue establishes feasibility and screening approaches for developing a Parkinson disease …
DP Bagchi, L Yu, JS Perlmutter, J Xu, RH Mach, Z Tu, PT Kotzbauer
PloS one 8 (2), e55031, 2013
Autorizações: US National Institutes of Health
Design, synthesis, and characterization of 3-(benzylidene) indolin-2-one derivatives as ligands for α-synuclein fibrils
W Chu, D Zhou, V Gaba, J Liu, S Li, X Peng, J Xu, D Dhavale, DP Bagchi, ...
Journal of medicinal chemistry 58 (15), 6002-6017, 2015
Autorizações: US National Institutes of Health
The novel sigma-2 receptor ligand SW43 stabilizes pancreas cancer progression in combination with gemcitabine
JR Hornick, J Xu, S Vangveravong, Z Tu, JB Mitchem, D Spitzer, ...
Molecular cancer 9, 1-11, 2010
Autorizações: US National Institutes of Health
Synthesis,[18F] radiolabeling, and evaluation of poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors for in vivo imaging of PARP-1 using positron emission tomography
D Zhou, W Chu, J Xu, LA Jones, X Peng, S Li, DL Chen, RH Mach
Bioorganic & medicinal chemistry 22 (5), 1700-1707, 2014
Autorizações: US National Institutes of Health, Doris Duke Charitable Foundation
Dopamine D3 receptor: A neglected participant in Parkinson Disease pathogenesis and treatment?
P Yang, JS Perlmutter, TLS Benzinger, JC Morris, J Xu
Ageing research reviews 57, 100994, 2020
Autorizações: US National Institutes of Health
Using SV119‐Gold Nanocage Conjugates to Eradicate Cancer Stem Cells Through a Combination of Photothermal and Chemo Therapies
T Sun, Y Wang, Y Wang, J Xu, X Zhao, S Vangveravong, RH Mach, Y Xia
Advanced healthcare materials 3 (8), 1283-1291, 2014
Autorizações: US National Institutes of Health
Development of a PET radiotracer for non-invasive imaging of the reactive oxygen species, superoxide, in vivo
W Chu, A Chepetan, D Zhou, KI Shoghi, J Xu, LL Dugan, RJ Gropler, ...
Organic & biomolecular chemistry 12 (25), 4421-4431, 2014
Autorizações: US National Institutes of Health
Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer’s disease
ECB Johnson, S Bian, RU Haque, EK Carter, CM Watson, BA Gordon, ...
Nature medicine 29 (8), 1979-1988, 2023
Autorizações: US National Institutes of Health, Canadian Institutes of Health Research …
Dopamine D1, D2, D3 Receptors, Vesicular Monoamine Transporter Type-2 (VMAT2) and Dopamine Transporter (DAT) Densities in Aged Human Brain
J Sun, J Xu, NJ Cairns, JS Perlmutter, RH Mach
PloS one 7 (11), e49483, 2012
Autorizações: US National Institutes of Health
Cross-inhibition of NMBR and GRPR signaling maintains normal histaminergic itch transmission
ZQ Zhao, L Wan, XY Liu, FQ Huo, H Li, DM Barry, S Krieger, S Kim, ZC Liu, ...
Journal of Neuroscience 34 (37), 12402-12414, 2014
Autorizações: US National Institutes of Health, National Natural Science Foundation of China
New N-substituted 9-azabicyclo [3.3. 1] nonan-3α-yl phenylcarbamate analogs as σ2 receptor ligands: synthesis, in vitro characterization, and evaluation as PET imaging and …
W Chu, J Xu, D Zhou, F Zhang, LA Jones, KT Wheeler, RH Mach
Bioorganic & medicinal chemistry 17 (3), 1222-1231, 2009
Autorizações: US National Institutes of Health
Use of multifunctional sigma-2 receptor ligand conjugates to trigger cancer-selective cell death signaling
D Spitzer, PO Simon Jr, H Kashiwagi, J Xu, C Zeng, S Vangveravong, ...
Cancer research 72 (1), 201-209, 2012
Autorizações: US National Institutes of Health
Synthesis and structure–activity relationship studies of conformationally flexible tetrahydroisoquinolinyl triazole carboxamide and triazole substituted benzamide analogues as …
S Bai, S Li, J Xu, X Peng, K Sai, W Chu, Z Tu, C Zeng, RH Mach
Journal of medicinal chemistry 57 (10), 4239-4251, 2014
Autorizações: US National Institutes of Health
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