| Epigenetic priming of memory updating during reconsolidation to attenuate remote fear memories J Gräff, NF Joseph, ME Horn, A Samiei, J Meng, J Seo, D Rei, AW Bero, ... Cell 156 (1), 261-276, 2014 | 392 | 2014 |
| Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site J Xu, C Zeng, W Chu, F Pan, JM Rothfuss, F Zhang, Z Tu, D Zhou, D Zeng, ... Nature communications 2 (1), 380, 2011 | 377 | 2011 |
| Alzheimer's therapeutics targeting amyloid beta 1–42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity NJ Izzo, J Xu, C Zeng, MJ Kirk, K Mozzoni, C Silky, C Rehak, R Yurko, ... PloS one 9 (11), e111899, 2014 | 212 | 2014 |
| Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid A Drieu, S Du, SE Storck, J Rustenhoven, Z Papadopoulos, T Dykstra, ... Nature 611 (7936), 585-593, 2022 | 184 | 2022 |
| Subcellular localization of sigma-2 receptors in breast cancer cells using two-photon and confocal microscopy C Zeng, S Vangveravong, J Xu, KC Chang, RS Hotchkiss, KT Wheeler, ... Cancer research 67 (14), 6708-6716, 2007 | 163 | 2007 |
| Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: applications in diagnostic imaging and therapy H Kashiwagi, JE McDunn, PO Simon, PS Goedegebuure, J Xu, L Jones, ... Molecular cancer 6, 1-12, 2007 | 150 | 2007 |
| Synthesis, radiolabeling, and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis D Zhou, W Chu, J Rothfuss, C Zeng, J Xu, L Jones, MJ Welch, RH Mach Bioorganic & medicinal chemistry letters 16 (19), 5041-5046, 2006 | 138 | 2006 |
| Synthesis and in vitro binding of N-phenyl piperazine analogs as potential dopamine D3 receptor ligands W Chu, Z Tu, E McElveen, J Xu, M Taylor, RR Luedtke, RH Mach Bioorganic & medicinal chemistry 13 (1), 77-87, 2005 | 136 | 2005 |
| Fluorine-18-Labeled Benzamide Analogues for Imaging the σ2 Receptor Status of Solid Tumors with Positron Emission Tomography Z Tu, J Xu, LA Jones, S Li, C Dumstorff, S Vangveravong, DL Chen, ... Journal of medicinal chemistry 50 (14), 3194-3204, 2007 | 132 | 2007 |
| Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study E Morenas-Rodríguez, Y Li, B Nuscher, N Franzmeier, C Xiong, ... The Lancet Neurology 21 (4), 329-341, 2022 | 127 | 2022 |
| Binding of the radioligand SIL23 to α-synuclein fibrils in Parkinson disease brain tissue establishes feasibility and screening approaches for developing a Parkinson disease … DP Bagchi, L Yu, JS Perlmutter, J Xu, RH Mach, Z Tu, PT Kotzbauer PloS one 8 (2), e55031, 2013 | 126 | 2013 |
| Design, synthesis, and characterization of 3-(benzylidene) indolin-2-one derivatives as ligands for α-synuclein fibrils W Chu, D Zhou, V Gaba, J Liu, S Li, X Peng, J Xu, D Dhavale, DP Bagchi, ... Journal of medicinal chemistry 58 (15), 6002-6017, 2015 | 122 | 2015 |
| The novel sigma-2 receptor ligand SW43 stabilizes pancreas cancer progression in combination with gemcitabine JR Hornick, J Xu, S Vangveravong, Z Tu, JB Mitchem, D Spitzer, ... Molecular cancer 9, 1-11, 2010 | 101 | 2010 |
| Synthesis,[18F] radiolabeling, and evaluation of poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors for in vivo imaging of PARP-1 using positron emission tomography D Zhou, W Chu, J Xu, LA Jones, X Peng, S Li, DL Chen, RH Mach Bioorganic & medicinal chemistry 22 (5), 1700-1707, 2014 | 97 | 2014 |
| Dopamine D3 receptor: A neglected participant in Parkinson Disease pathogenesis and treatment? P Yang, JS Perlmutter, TLS Benzinger, JC Morris, J Xu Ageing research reviews 57, 100994, 2020 | 96 | 2020 |
| Using SV119‐Gold Nanocage Conjugates to Eradicate Cancer Stem Cells Through a Combination of Photothermal and Chemo Therapies T Sun, Y Wang, Y Wang, J Xu, X Zhao, S Vangveravong, RH Mach, Y Xia Advanced healthcare materials 3 (8), 1283-1291, 2014 | 90 | 2014 |
| Development of a PET radiotracer for non-invasive imaging of the reactive oxygen species, superoxide, in vivo W Chu, A Chepetan, D Zhou, KI Shoghi, J Xu, LL Dugan, RJ Gropler, ... Organic & biomolecular chemistry 12 (25), 4421-4431, 2014 | 89 | 2014 |
| [3H] N-[4-(3, 4-dihydro-6, 7-dimethoxyisoquinolin-2 (1H)-yl) butyl]-2-methoxy-5-methylbenzamide: a novel sigma-2 receptor probe J Xu, Z Tu, LA Jones, S Vangveravong, KT Wheeler, RH Mach European journal of pharmacology 525 (1-3), 8-17, 2005 | 84 | 2005 |
| Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer’s disease ECB Johnson, S Bian, RU Haque, EK Carter, CM Watson, BA Gordon, ... Nature medicine 29 (8), 1979-1988, 2023 | 82 | 2023 |
| Dopamine D1, D2, D3 Receptors, Vesicular Monoamine Transporter Type-2 (VMAT2) and Dopamine Transporter (DAT) Densities in Aged Human Brain J Sun, J Xu, NJ Cairns, JS Perlmutter, RH Mach PloS one 7 (11), e49483, 2012 | 80 | 2012 |
