| Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease M Cavazzana-Calvo, S Hacein-Bey, GS Basile, F Gross, E Yvon, ... Science 288 (5466), 669-672, 2000 | 3555 | 2000 |
| Autoantibodies against type I IFNs in patients with life-threatening COVID-19 P Bastard, LB Rosen, Q Zhang, E Michailidis, HH Hoffmann, Y Zhang, ... Science 370 (6515), eabd4585, 2020 | 2674 | 2020 |
| X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy RS Wildin, F Ramsdell, J Peake, F Faravelli, JL Casanova, N Buist, ... Nature genetics 27 (1), 18-20, 2001 | 2356 | 2001 |
| Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 Q Zhang, P Bastard, Z Liu, J Le Pen, M Moncada-Velez, J Chen, M Ogishi, ... Science 370 (6515), eabd4570, 2020 | 2294 | 2020 |
| Human inborn errors of immunity: 2019 update on the classification from the International Union of Immunological Societies Expert Committee SG Tangye, W Al-Herz, A Bousfiha, T Chatila, C Cunningham-Rundles, ... Journal of clinical immunology 40, 24-64, 2020 | 2048 | 2020 |
| Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors J Cros, N Cagnard, K Woollard, N Patey, SY Zhang, B Senechal, A Puel, ... Immunity 33 (3), 375-386, 2010 | 1554 | 2010 |
| TLR3 deficiency in patients with herpes simplex encephalitis SY Zhang, E Jouanguy, S Ugolini, A Smahi, G Elain, P Romero, D Segal, ... science 317 (5844), 1522-1527, 2007 | 1317 | 2007 |
| Genetic dissection of immunity to mycobacteria: the human model JL Casanova, L Abel Annual review of immunology 20 (1), 581-620, 2002 | 1261 | 2002 |
| Kawasaki-like multisystem inflammatory syndrome in children during the covid-19 pandemic in Paris, France: prospective observational study J Toubiana, C Poirault, A Corsia, F Bajolle, J Fourgeaud, F Angoulvant, ... bmj 369, 2020 | 1253 | 2020 |
| Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity A Puel, S Cypowyj, J Bustamante, JF Wright, L Liu, HK Lim, M Migaud, ... Science 332 (6025), 65-68, 2011 | 1168 | 2011 |
| Interferon-γ–receptor deficiency in an infant with fatal bacille Calmette–Guérin infection E Jouanguy, F Altare, S Lamhamedi, P Revy, JF Emile, M Newport, ... New England Journal of Medicine 335 (26), 1956-1962, 1996 | 1132 | 1996 |
| Pyogenic bacterial infections in humans with IRAK-4 deficiency C Picard, A Puel, M Bonnet, CL Ku, J Bustamante, K Yang, C Soudais, ... Science 299 (5615), 2076-2079, 2003 | 1106 | 2003 |
| Interleukin-36–receptor antagonist deficiency and generalized pustular psoriasis S Marrakchi, P Guigue, BR Renshaw, A Puel, XY Pei, S Fraitag, J Zribi, ... New England Journal of Medicine 365 (7), 620-628, 2011 | 1096 | 2011 |
| Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency F Altare, A Durandy, D Lammas, JF Emile, S Lamhamedi, F Le Deist, ... Science 280 (5368), 1432-1435, 1998 | 1071 | 1998 |
| Severe Mycobacterial and Salmonella Infections in Interleukin-12 Receptor-Deficient Patients R Jong, F Altare, IA Haagen, DG Elferink, T Boer, ... Science 280 (5368), 1435-1438, 1998 | 1030 | 1998 |
| Human blood IgM “memory” B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire S Weller, MC Braun, BK Tan, A Rosenwald, C Cordier, ME Conley, ... Blood 104 (12), 3647-3654, 2004 | 1018 | 2004 |
| International union of immunological societies: 2017 primary immunodeficiency diseases committee report on inborn errors of immunity C Picard, H Bobby Gaspar, W Al-Herz, A Bousfiha, JL Casanova, ... Journal of clinical immunology 38, 96-128, 2018 | 960 | 2018 |
| X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-κB signaling R Döffinger, A Smahi, C Bessia, F Geissmann, J Feinberg, A Durandy, ... Nature genetics 27 (3), 277-285, 2001 | 955 | 2001 |
| Impaired response to interferon-α/β and lethal viral disease in human STAT1 deficiency S Dupuis, E Jouanguy, S Al-Hajjar, C Fieschi, IZ Al-Mohsen, S Al-Jumaah, ... Nature genetics 33 (3), 388-391, 2003 | 946 | 2003 |
| IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases MWL Teng, EP Bowman, JJ McElwee, MJ Smyth, JL Casanova, ... Nature medicine 21 (7), 719-729, 2015 | 936 | 2015 |
Shen-Ying ZhangAssistant Professor of Clinical Investigation, The Rockefeller UniversityE-mail confirmado em rockefeller.edu
