| Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids BS Freedman, CR Brooks, AQ Lam, H Fu, R Morizane, V Agrawal, ... Nature communications 6 (1), 8715, 2015 | 775 | 2015 |
| Evolutionarily conserved replication timing profiles predict long-range chromatin interactions and distinguish closely related cell types T Ryba, I Hiratani, J Lu, M Itoh, M Kulik, J Zhang, TC Schulz, AJ Robins, ... Genome research 20 (6), 761-770, 2010 | 697 | 2010 |
| The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity W Wang, L Wang, J Lu, SL Siedlak, H Fujioka, J Liang, S Jiang, X Ma, ... Nature medicine 22 (8), 869-878, 2016 | 436 | 2016 |
| G9a selectively represses a class of late-replicating genes at the nuclear periphery T Yokochi, K Poduch, T Ryba, J Lu, I Hiratani, M Tachibana, Y Shinkai, ... Proceedings of the National Academy of Sciences 106 (46), 19363-19368, 2009 | 186 | 2009 |
| Proliferation-dependent and cell cycle–regulated transcription of mouse pericentric heterochromatin J Lu, DM Gilbert Journal of Cell Biology 179 (3), 411-421, 2007 | 180 | 2007 |
| Replication timing and transcriptional control: beyond cause and effect—part II I Hiratani, S Takebayashi, J Lu, DM Gilbert Current opinion in genetics & development 19 (2), 142-149, 2009 | 179 | 2009 |
| Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition G Carraro, J Langerman, S Sabri, Z Lorenzana, A Purkayastha, G Zhang, ... Nature medicine 27 (5), 806-814, 2021 | 148 | 2021 |
| Space and time in the nucleus developmental control of replication timing and chromosome architecture DM Gilbert, SI Takebayashi, T Ryba, J Lu, BD Pope, KA Wilson, I Hiratani Cold Spring Harbor symposia on quantitative biology 75, 143-153, 2010 | 121 | 2010 |
| Molecular cloning of a novel human gene encoding histone acetyltransferase-like protein involved in transcriptional activation of hTERT J Lv, H Liu, Q Wang, Z Tang, L Hou, B Zhang Biochemical and biophysical research communications 311 (2), 506-513, 2003 | 105 | 2003 |
| G2 phase chromatin lacks determinants of replication timing J Lu, F Li, CS Murphy, MW Davidson, DM Gilbert Journal of Cell Biology 189 (6), 967-980, 2010 | 62 | 2010 |
| The distribution of genomic variations in human iPSCs is related to replication-timing reorganization during reprogramming J Lu, H Li, M Hu, T Sasaki, A Baccei, DM Gilbert, JS Liu, JJ Collins, ... Cell reports 7 (1), 70-78, 2014 | 33 | 2014 |
| Rho/SMAD/mTOR triple inhibition enables long-term expansion of human neonatal tracheal aspirate-derived airway basal cell-like cells J Lu, X Zhu, JE Shui, L Xiong, T Gierahn, C Zhang, M Wood, S Hally, ... Pediatric Research 89 (3), 502-509, 2021 | 27 | 2021 |
| A multimodal iPSC platform for cystic fibrosis drug testing A Berical, RE Lee, J Lu, ML Beermann, JA Le Suer, A Mithal, D Thomas, ... Nature Communications 13 (1), 4270, 2022 | 26 | 2022 |
| Molecular cloning and characterization of a human gene involved in transcriptional regulation of hTERT Z Tang, Y Zhao, F Mei, S Yang, X Li, J Lv, L Hou, B Zhang Biochemical and biophysical research communications 324 (4), 1324-1332, 2004 | 26 | 2004 |
| Cell cycle regulated transcription of heterochromatin in mammals vs. fission yeast: functional conservation or coincidence? J Lu, DM Gilbert Cell Cycle 7 (13), 1907-1910, 2008 | 22 | 2008 |
| Single-cell RNA sequencing reveals metallothionein heterogeneity during hESC differentiation to definitive endoderm J Lu, A Baccei, EL da Rocha, C Guillermier, S McManus, LA Finney, ... Stem cell research 28, 48-55, 2018 | 18 | 2018 |
| De Novo Generation of Pulmonary Ionocytes from Normal and Cystic Fibrosis Human Induced Pluripotent Stem Cells R Wang, C Simone-Roach, J Lindstrom-Vautrin, F Wang, S Rollins, ... American Journal of Respiratory and Critical Care Medicine 207 (9), 1249-1253, 2023 | 13 | 2023 |
| Lung-resident mesenchymal stromal cells reveal transcriptional dynamics of lung development in preterm infants R Spadafora, J Lu, RS Khetani, C Zhang, A Iberg, H Li, Y Shi, PH Lerou American journal of respiratory and critical care medicine 198 (7), 961-964, 2018 | 10 | 2018 |
| Influence of ATM-Mediated DNA Damage Response on Genomic Variation in Human Induced Pluripotent Stem Cells J Lu, H Li, A Baccei, T Sasaki, DM Gilbert, PH Lerou Stem cells and development 25 (9), 740-747, 2016 | 10 | 2016 |
| Multi-scale imaging and informatics pipeline for in situ pluripotent stem cell analysis BR Gorman, J Lu, A Baccei, NC Lowry, JE Purvis, RS Mangoubi, ... PLoS One 9 (12), e116037, 2014 | 10 | 2014 |
David M. GilbertSan Diego Biomedical Research InstituteE-mail confirmado em sdbri.org