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Ryan Terry-Lorenzo
Ryan Terry-Lorenzo
Neurocrine Biosciences
E-mail confirmado em neurocrine.com
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Piccolo modulation of Synapsin1a dynamics regulates synaptic vesicle exocytosis
S Leal-Ortiz, CL Waites, R Terry-Lorenzo, P Zamorano, ED Gundelfinger, ...
The Journal of cell biology 181 (5), 831-846, 2008
1652008
Targeting protein phosphatase 1 (PP1) to the actin cytoskeleton: the neurabin I/PP1 complex regulates cell morphology
CJ Oliver, RT Terry-Lorenzo, E Elliott, WAC Bloomer, S Li, DL Brautigan, ...
Molecular and cellular biology, 2002
1542002
Formation of Golgi-derived active zone precursor vesicles
C Maas, VI Torres, WD Altrock, S Leal-Ortiz, D Wagh, RT Terry-Lorenzo, ...
Journal of Neuroscience 32 (32), 11095-11108, 2012
1122012
Neurabin/protein phosphatase-1 complex regulates dendritic spine morphogenesis and maturation
RT Terry-Lorenzo, DW Roadcap, T Otsuka, TA Blanpied, PL Zamorano, ...
Molecular biology of the cell 16 (5), 2349-2362, 2005
1102005
The neuronal actin-binding proteins, neurabin I and neurabin II, recruit specific isoforms of protein phosphatase-1 catalytic subunits
RT Terry-Lorenzo, LC Carmody, JW Voltz, JH Connor, S Li, FD Smith, ...
Journal of Biological Chemistry 277 (31), 27716-27724, 2002
1082002
Neurabins recruit protein phosphatase-1 and inhibitor-2 to the actin cytoskeleton
RT Terry-Lorenzo, E Elliot, DC Weiser, TD Prickett, DL Brautigan, ...
Journal of Biological Chemistry 277 (48), 46535-46543, 2002
1022002
Neurofilament-L is a protein phosphatase-1-binding protein associated with neuronal plasma membrane and post-synaptic density
RT Terry-Lorenzo, M Inoue, JH Connor, TAJ Haystead, BN Armbruster, ...
Journal of Biological Chemistry 275 (4), 2439-2446, 2000
912000
Transsynaptic signaling by postsynaptic synapse-associated protein 97
MP Regalado, RT Terry-Lorenzo, CL Waites, CC Garner, RC Malenka
Journal of Neuroscience 26 (8), 2343-2357, 2006
842006
Chemical proteomics identifies Nampt as the target of CB30865, an orphan cytotoxic compound
TC Fleischer, BR Murphy, JS Flick, RT Terry-Lorenzo, ZH Gao, T Davis, ...
Chemistry & Biology 17 (6), 659-664, 2010
622010
Analogues of 4-[(7-Bromo-2-methyl-4-oxo-3H-quinazolin-6-yl)methylprop-2-ynylamino]-N-(3-pyridylmethyl)benzamide (CB-30865) as Potent Inhibitors of …
JW Lockman, BR Murphy, DF Zigar, WR Judd, PM Slattum, ZH Gao, ...
Journal of Medicinal Chemistry 53 (24), 8734-8746, 2010
462010
Longitudinal two-photon imaging in somatosensory cortex of behaving mice reveals dendritic spine formation enhancement by subchronic administration of low-dose ketamine
E Pryazhnikov, E Mugantseva, P Casarotto, J Kolikova, SM Fred, ...
Scientific reports 8 (1), 6464, 2018
442018
Piccolo directs activity dependent F-actin assembly from presynaptic active zones via Daam1
D Wagh, R Terry-Lorenzo, CL Waites, SA Leal-Ortiz, C Maas, RJ Reimer, ...
PLoS One 10 (4), e0120093, 2015
442015
Novel human D-amino acid oxidase inhibitors stabilize an active-site lid-open conformation
RT Terry-Lorenzo, LE Chun, SP Brown, MLR Heffernan, QK Fang, ...
Bioscience reports 34 (4), e00133, 2014
342014
Trio, a rho family GEF, interacts with the presynaptic active zone proteins piccolo and bassoon
RT Terry-Lorenzo, VI Torres, D Wagh, J Galaz, SK Swanson, L Florens, ...
PLoS One 11 (12), e0167535, 2016
242016
High-throughput screening strategy identifies allosteric, covalent human D-amino acid oxidase inhibitor
RT Terry-Lorenzo, K Masuda, K Sugao, QK Fang, MA Orsini, S Sacchi, ...
Journal of Biomolecular Screening 20 (10), 1218-1231, 2015
132015
Compounds and therapeutic uses thereof
JA Willardsen, JW Lockman, BR Murphy, WR Judd, IC Kim, SH Kim, ...
US Patent App. 13/708,235, 2013
132013
Compounds and therapeutic uses thereof
JA Willardsen, JW Lockman, BR Murphy, WR Judd, IC Kim, SH Kim, ...
US Patent App. 13/601,879, 2012
102012
Basal NAD levels and Nampt expression correlate with in vitro and in vivo sensitivity of tumor cell lines to the Nampt inhibitor MPC-9528
JJ Boniface, VR Baichwal, DM Cimbora, L DeMie, TC Fleischer, ...
Cancer Research 71 (8_Supplement), 577-577, 2011
12011
Coadministration of nicotinic acid with the Nampt inhibitor MPC-9528 enhances antitumor activity in Naprt deficient cancer cells in culture and in xenografts
TC Fleischer, VR Baichwal, JJ Boniface, DM Cimbora, L DeMie, ...
Cancer Research 71 (8_Supplement), 3526-3526, 2011
12011
The Nampt inhibitor MPC-9528 synergizes with DNA damaging agents
RT Terry-Lorenzo, TB Douce, HA Austin, JJ Boniface, DM Cimbora, ...
Cancer Research 71 (8_Supplement), 2551-2551, 2011
12011
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