Predicting sepsis severity at first clinical presentation: The role of endotypes and mechanistic signatures A Baghela, OM Pena, AH Lee, B Baquir, R Falsafi, A An, SW Farmer, ... EBioMedicine 75, 2022 | 106 | 2022 |
Exploring the pathophysiology of post-sepsis syndrome to identify therapeutic opportunities EC van der Slikke, AY An, REW Hancock, HR Bouma EBioMedicine 61, 2020 | 74 | 2020 |
Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity A Jan, B Jansonius, A Delaidelli, F Bhanshali, YA An, N Ferreira, ... Acta neuropathologica communications 6, 1-17, 2018 | 62 | 2018 |
An overview of biological and computational methods for designing mechanism-informed anti-biofilm agents AY An, KYG Choi, AS Baghela, REW Hancock Frontiers in Microbiology 12, 640787, 2021 | 38 | 2021 |
Predicting severity in COVID-19 disease using sepsis blood gene expression signatures A Baghela, A An, P Zhang, E Acton, J Gauthier, E Brunet-Ratnasingham, ... Scientific Reports 13 (1), 1247, 2023 | 27 | 2023 |
Predicting sepsis severity at first clinical presentation: The role of endotypes and mechanistic signatures. EBioMedicine. 2022; 75: 103776 A Baghela, OM Pena, AH Lee, B Baquir, R Falsafi, A An, SW Farmer, ... | 10 | 2021 |
Severe COVID-19 and non-COVID-19 severe sepsis converge transcriptionally after a week in the intensive care unit, indicating common disease mechanisms AY An, A Baghela, P Zhang, R Falsafi, AH Lee, U Trahtemberg, AJ Baker, ... Frontiers in Immunology 14, 1167917, 2023 | 8 | 2023 |
Exploring the pathophysiology of post-sepsis syndrome to identify therapeutic opportunities. EBioMedicine, 61, 103044 EC Van der Slikke, AY An, REW Hancock, HR Bouma | 7 | 2020 |
Post-COVID symptoms are associated with endotypes reflecting poor inflammatory and hemostatic modulation AY An, A Baghela, PGY Zhang, TM Blimkie, J Gauthier, DE Kaufmann, ... Frontiers in Immunology 14, 1243689, 2023 | 4 | 2023 |
NtrBC Selectively Regulates Host-Pathogen Interactions, Virulence, and Ciprofloxacin Susceptibility of Pseudomonas aeruginosa MA Alford, B Baquir, A An, KYG Choi, REW Hancock Frontiers in Cellular and Infection Microbiology 11, 694789, 2021 | 4 | 2021 |
Human-induced pluripotent stem cell–derived macrophages for studying infection biology and immunology B Baquir, AY An, AHY Lee, REW Hancock Current Progress in iPSC-derived Cell Types, 1-22, 2021 | 2 | 2021 |
Persistence is key: unresolved immune dysfunction is lethal in both COVID-19 and non-COVID-19 sepsis AY An, A Baghela, P Zhang, R Falsafi, AH Lee, U Trahtemberg, AJ Baker, ... Frontiers in Immunology 14, 1254873, 2023 | 1 | 2023 |
Predictive gene expression signature diagnoses neonatal sepsis before clinical presentation AY An, E Acton, OT Idoko, CP Shannon, TM Blimkie, R Falsafi, O Wariri, ... EBioMedicine, 2024 | | 2024 |
DNA Methylation signatures underpinning blood neutrophil to lymphocyte ratio during first week of human life D Martino, N Kresoje, N Amenyogbe, R Ben-Othman, B Cai, M Lo, ... Nature Communications 15 (1), 8167, 2024 | | 2024 |
Facilitating pathway and network based analysis of RNA-Seq data with pathlinkR TM Blimkie, A An, REW Hancock PLOS Computational Biology 20 (9), e1012422, 2024 | | 2024 |
Supervised Multi-Omics Integration Identifies Differential Biomarkers of COVID Versus Non-COVID Acute Respiratory Distress Syndrome J Tai, E Acton, E Churcher, CM Vaswani, G Tan, J Tsoporis, R Hancock, ... A103. DYSREGULATED PATHWAYS IN SEPSIS AND LUNG INJURY: SEARCHING FOR …, 2024 | | 2024 |
Dynamic gene expression analysis reveals distinct severity phases of immune and cellular dysregulation in COVID-19 AY An, A Baghela, P Zhang, TM Blimkie, J Gauthier, DE Kaufmann, ... bioRxiv, 2023.11. 04.565404, 2023 | | 2023 |
Dynamic analysis of gene expression trajectories in sepsis and severe COVID-19 AY An University of British Columbia, 2023 | | 2023 |