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Andy Y. An
Andy Y. An
E-mail confirmado em alumni.ubc.ca
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Predicting sepsis severity at first clinical presentation: The role of endotypes and mechanistic signatures
A Baghela, OM Pena, AH Lee, B Baquir, R Falsafi, A An, SW Farmer, ...
EBioMedicine 75, 2022
1062022
Exploring the pathophysiology of post-sepsis syndrome to identify therapeutic opportunities
EC van der Slikke, AY An, REW Hancock, HR Bouma
EBioMedicine 61, 2020
742020
Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity
A Jan, B Jansonius, A Delaidelli, F Bhanshali, YA An, N Ferreira, ...
Acta neuropathologica communications 6, 1-17, 2018
622018
An overview of biological and computational methods for designing mechanism-informed anti-biofilm agents
AY An, KYG Choi, AS Baghela, REW Hancock
Frontiers in Microbiology 12, 640787, 2021
382021
Predicting severity in COVID-19 disease using sepsis blood gene expression signatures
A Baghela, A An, P Zhang, E Acton, J Gauthier, E Brunet-Ratnasingham, ...
Scientific Reports 13 (1), 1247, 2023
272023
Predicting sepsis severity at first clinical presentation: The role of endotypes and mechanistic signatures. EBioMedicine. 2022; 75: 103776
A Baghela, OM Pena, AH Lee, B Baquir, R Falsafi, A An, SW Farmer, ...
102021
Severe COVID-19 and non-COVID-19 severe sepsis converge transcriptionally after a week in the intensive care unit, indicating common disease mechanisms
AY An, A Baghela, P Zhang, R Falsafi, AH Lee, U Trahtemberg, AJ Baker, ...
Frontiers in Immunology 14, 1167917, 2023
82023
Exploring the pathophysiology of post-sepsis syndrome to identify therapeutic opportunities. EBioMedicine, 61, 103044
EC Van der Slikke, AY An, REW Hancock, HR Bouma
72020
Post-COVID symptoms are associated with endotypes reflecting poor inflammatory and hemostatic modulation
AY An, A Baghela, PGY Zhang, TM Blimkie, J Gauthier, DE Kaufmann, ...
Frontiers in Immunology 14, 1243689, 2023
42023
NtrBC Selectively Regulates Host-Pathogen Interactions, Virulence, and Ciprofloxacin Susceptibility of Pseudomonas aeruginosa
MA Alford, B Baquir, A An, KYG Choi, REW Hancock
Frontiers in Cellular and Infection Microbiology 11, 694789, 2021
42021
Human-induced pluripotent stem cell–derived macrophages for studying infection biology and immunology
B Baquir, AY An, AHY Lee, REW Hancock
Current Progress in iPSC-derived Cell Types, 1-22, 2021
22021
Persistence is key: unresolved immune dysfunction is lethal in both COVID-19 and non-COVID-19 sepsis
AY An, A Baghela, P Zhang, R Falsafi, AH Lee, U Trahtemberg, AJ Baker, ...
Frontiers in Immunology 14, 1254873, 2023
12023
Predictive gene expression signature diagnoses neonatal sepsis before clinical presentation
AY An, E Acton, OT Idoko, CP Shannon, TM Blimkie, R Falsafi, O Wariri, ...
EBioMedicine, 2024
2024
DNA Methylation signatures underpinning blood neutrophil to lymphocyte ratio during first week of human life
D Martino, N Kresoje, N Amenyogbe, R Ben-Othman, B Cai, M Lo, ...
Nature Communications 15 (1), 8167, 2024
2024
Facilitating pathway and network based analysis of RNA-Seq data with pathlinkR
TM Blimkie, A An, REW Hancock
PLOS Computational Biology 20 (9), e1012422, 2024
2024
Supervised Multi-Omics Integration Identifies Differential Biomarkers of COVID Versus Non-COVID Acute Respiratory Distress Syndrome
J Tai, E Acton, E Churcher, CM Vaswani, G Tan, J Tsoporis, R Hancock, ...
A103. DYSREGULATED PATHWAYS IN SEPSIS AND LUNG INJURY: SEARCHING FOR …, 2024
2024
Dynamic gene expression analysis reveals distinct severity phases of immune and cellular dysregulation in COVID-19
AY An, A Baghela, P Zhang, TM Blimkie, J Gauthier, DE Kaufmann, ...
bioRxiv, 2023.11. 04.565404, 2023
2023
Dynamic analysis of gene expression trajectories in sepsis and severe COVID-19
AY An
University of British Columbia, 2023
2023
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