David A. Sinclair

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184 artigos

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Rafael De CaboTranslational Gerontology Branch, National Institute on AgingE-mail confirmado em grc.nia.nih.gov
Joseph A. BaurProfessor of Physiology, University of PennsylvaniaE-mail confirmado em mail.med.upenn.edu
Haim CohenBiology professorE-mail confirmado em biu.ac.il
Lindsay WuHevolution / American Federation for Aging Research Investigator, UNSW SydneyE-mail confirmado em unsw.edu.au
Ana P. GomesH. Lee Moffitt Cancer CenterE-mail confirmado em moffitt.org
Basil HubbardAssociate Professor, University of TorontoE-mail confirmado em utoronto.ca
Jason WoodBrown UniversityE-mail confirmado em brown.edu
Dudley LammingAssociate Professor of Medicine, University of Wisconsin-MadisonE-mail confirmado em medicine.wisc.edu
Carlos PalmeiraProfessor, Universidade de CoimbraE-mail confirmado em uc.pt
sarah mitchellPrinceton UniversityE-mail confirmado em princeton.edu
Angela V. HafnerMITE-mail confirmado em mit.edu
Alice KaneLing/Obrzut Assistant Professor, Institute for Systems BiologyE-mail confirmado em isbscience.org
Michael BonkowskiAssistant Research Professor - Lab Director - Department of Dermatology- Northwestern FeinburgE-mail confirmado em northwestern.edu
Rolo APE-mail confirmado em ci.uc.pt
Nathan L PriceStaff Scientist, Experimental Gerontology Section, NIAE-mail confirmado em nih.gov
Yuancheng (Ryan) LuLSRF and AFAR Postdoctoral Fellow, MIT/WhiteheadE-mail confirmado em wi.mit.edu
Rozalyn AndersonUniversity of Wisconsin MadisonE-mail confirmado em wisc.edu
Professor Nigel TurnerVictor Chang Cardiac Research InstituteE-mail confirmado em victorchang.edu.au
Sean M. Armour, Ph.D.Head of DiscoveryE-mail confirmado em sparktx.com
Joao TeodoroCenter fo Neurosciences and Cell Biology of the University of CoimbraE-mail confirmado em ci.uc.pt

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David A. Sinclair

Harvard Medical School (Genetics)

E-mail confirmado em hms.harvard.edu - Página inicial

Aging metabolism chromatin


Título Ordenar por citações Ordenar por ano Ordenar por título	Citado por Citado por	Ano
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹ DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021	11196	2021
Resveratrol improves health and survival of mice on a high-calorie diet JA Baur, KJ Pearson, NL Price, HA Jamieson, C Lerin, A Kalra, ... Nature 444 (7117), 337-342, 2006	5480	2006
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan KJ Bitterman, HY Cohen, DW Lamming, S Lavu, JG Wood, RE Zipkin, ... Nature 425, 191-196, 2003	4935*	2003
Therapeutic potential of resveratrol: the in vivo evidence JA Baur, DA Sinclair Nature reviews Drug discovery 5 (6), 493-506, 2006	4893	2006
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase A Brunet, LB Sweeney, JF Sturgill, KF Chua, PL Greer, Y Lin, H Tran, ... science 303 (5666), 2011-2015, 2004	3881	2004
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase HY Cohen, C Miller, KJ Bitterman, NR Wall, B Hekking, B Kessler, ... science 305 (5682), 390-392, 2004	2450	2004
Mammalian sirtuins: biological insights and disease relevance MC Haigis, DA Sinclair Annual Review of Pathology: Mechanisms of Disease 5 (1), 253-295, 2010	2385	2010
Sirtuin activators mimic caloric restriction and delay ageing in metazoans JG Wood, B Rogina, S Lavu, K Howitz, SL Helfand, M Tatar, D Sinclair Nature 430 (7000), 686-689, 2004	2339	2004
Sirtuins in mammals: insights into their biological function S Michan, D Sinclair Biochemical Journal 404 (1), 1-13, 2007	2170	2007
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes JC Milne, PD Lambert, S Schenk, DP Carney, JJ Smith, DJ Gagne, L Jin, ... Nature 450 (7170), 712-716, 2007	2055	2007
Extrachromosomal rDNA circles—a cause of aging in yeast DA Sinclair, L Guarente Cell 91 (7), 1033-1042, 1997	1880	1997
SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function NL Price, AP Gomes, AJY Ling, FV Duarte, A Martin-Montalvo, BJ North, ... Cell metabolism 15 (5), 675-690, 2012	1734	2012
The intersection between aging and cardiovascular disease BJ North, DA Sinclair Circulation research 110 (8), 1097-1108, 2012	1676	2012
Metformin improves healthspan and lifespan in mice A Martin-Montalvo, EM Mercken, SJ Mitchell, HH Palacios, PL Mote, ... Nature communications 4 (1), 2192, 2013	1560	2013
Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging AP Gomes, NL Price, AJY Ling, JJ Moslehi, MK Montgomery, L Rajman, ... Cell 155 (7), 1624-1638, 2013	1557	2013
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span KJ Pearson, JA Baur, KN Lewis, L Peshkin, NL Price, N Labinskyy, ... Cell metabolism 8 (2), 157-168, 2008	1404	2008
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis D Kim, MD Nguyen, MM Dobbin, A Fischer, F Sananbenesi, JT Rodgers, ... The EMBO journal 26 (13), 3169-3179, 2007	1315	2007
Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1 KJ Bitterman, RM Anderson, HY Cohen, M Latorre-Esteves, DA Sinclair Journal of Biological Chemistry 277 (47), 45099-45107, 2002	1304	2002
Why does COVID-19 disproportionately affect older people? AL Mueller, MS McNamara, DA Sinclair Aging (albany NY) 12 (10), 9959, 2020	1261	2020
Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival H Yang, T Yang, JA Baur, E Perez, T Matsui, JJ Carmona, DW Lamming, ... Cell 130 (6), 1095-1107, 2007	1141	2007

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