Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function M Sukumar, J Liu, Y Ji, M Subramanian, JG Crompton, Z Yu, ... The Journal of clinical investigation 123 (10), 4479-4488, 2013 | 960 | 2013 |
Identification of essential genes for cancer immunotherapy SJ Patel, NE Sanjana, RJ Kishton, A Eidizadeh, SK Vodnala, M Cam, ... Nature 548 (7669), 537-542, 2017 | 859 | 2017 |
Ionic immune suppression within the tumour microenvironment limits T cell effector function R Eil, SK Vodnala, D Clever, CA Klebanoff, M Sukumar, JH Pan, ... Nature 537 (7621), 539-543, 2016 | 596 | 2016 |
Th17 cells are long lived and retain a stem cell-like molecular signature P Muranski, ZA Borman, SP Kerkar, CA Klebanoff, Y Ji, L Sanchez-Perez, ... Immunity 35 (6), 972-985, 2011 | 512 | 2011 |
Metabolic regulation of T cell longevity and function in tumor immunotherapy RJ Kishton, M Sukumar, NP Restifo Cell metabolism 26 (1), 94-109, 2017 | 481 | 2017 |
T cell stemness and dysfunction in tumors are triggered by a common mechanism SK Vodnala, R Eil, RJ Kishton, M Sukumar, TN Yamamoto, NH Ha, ... Science 363 (6434), eaau0135, 2019 | 460 | 2019 |
Mitochondrial membrane potential identifies cells with enhanced stemness for cellular therapy M Sukumar, J Liu, GU Mehta, SJ Patel, R Roychoudhuri, JG Crompton, ... Cell metabolism 23 (1), 63-76, 2016 | 373 | 2016 |
Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics JG Crompton, M Sukumar, R Roychoudhuri, D Clever, A Gros, RL Eil, ... Cancer research 75 (2), 296-305, 2015 | 365 | 2015 |
BACH2 regulates CD8+ T cell differentiation by controlling access of AP-1 factors to enhancers R Roychoudhuri, D Clever, P Li, Y Wakabayashi, KM Quinn, CA Klebanoff, ... Nature immunology 17 (7), 851-860, 2016 | 299 | 2016 |
Memory T cell–driven differentiation of naive cells impairs adoptive immunotherapy CA Klebanoff, CD Scott, AJ Leonardi, TN Yamamoto, AC Cruz, C Ouyang, ... The Journal of clinical investigation 126 (1), 318-334, 2016 | 256 | 2016 |
Oxygen sensing by T cells establishes an immunologically tolerant metastatic niche D Clever, R Roychoudhuri, MG Constantinides, MH Askenase, ... Cell 166 (5), 1117-1131. e14, 2016 | 249 | 2016 |
Repression of the DNA-binding inhibitor Id3 by Blimp-1 limits the formation of memory CD8+ T cells Y Ji, Z Pos, M Rao, CA Klebanoff, Z Yu, M Sukumar, RN Reger, ... Nature immunology 12 (12), 1230-1237, 2011 | 247 | 2011 |
Inhibition of AKT signaling uncouples T cell differentiation from expansion for receptor-engineered adoptive immunotherapy CA Klebanoff, JG Crompton, AJ Leonardi, TN Yamamoto, SS Chandran, ... JCI insight 2 (23), 2017 | 203 | 2017 |
Cish actively silences TCR signaling in CD8+ T cells to maintain tumor tolerance DC Palmer, GC Guittard, Z Franco, JG Crompton, RL Eil, SJ Patel, Y Ji, ... Journal of Experimental Medicine 212 (12), 2095-2113, 2015 | 200 | 2015 |
Retinoic acid controls the homeostasis of pre-cDC–derived splenic and intestinal dendritic cells CA Klebanoff, SP Spencer, P Torabi-Parizi, JR Grainger, R Roychoudhuri, ... Journal of Experimental Medicine 210 (10), 1961-1976, 2013 | 164 | 2013 |
Uncoupling T‐cell expansion from effector differentiation in cell‐based immunotherapy JG Crompton, M Sukumar, NP Restifo Immunological reviews 257 (1), 264-276, 2014 | 152 | 2014 |
Multi-phenotype CRISPR-Cas9 screen identifies p38 kinase as a target for adoptive immunotherapies D Gurusamy, AN Henning, TN Yamamoto, Z Yu, N Zacharakis, S Krishna, ... Cancer cell 37 (6), 818-833. e9, 2020 | 138 | 2020 |
Lineage relationship of CD8+ T cell subsets is revealed by progressive changes in the epigenetic landscape JG Crompton, M Narayanan, S Cuddapah, R Roychoudhuri, Y Ji, W Yang, ... Cellular & molecular immunology 13 (4), 502-513, 2016 | 131 | 2016 |
Nutrient competition: a new axis of tumor immunosuppression M Sukumar, R Roychoudhuri, NP Restifo Cell 162 (6), 1206-1208, 2015 | 127 | 2015 |
miR-155 augments CD8+ T-cell antitumor activity in lymphoreplete hosts by enhancing responsiveness to homeostatic γc cytokines Y Ji, C Wrzesinski, Z Yu, J Hu, S Gautam, NV Hawk, WG Telford, ... Proceedings of the National Academy of Sciences 112 (2), 476-481, 2015 | 108 | 2015 |