High-throughput crystallization: polymorphs, salts, co-crystals and solvates of pharmaceutical solids SL Morissette, Ö Almarsson, ML Peterson, JF Remenar, MJ Read, ... Advanced drug delivery reviews 56 (3), 275-300, 2004 | 1236 | 2004 |
Crystal engineering of the composition of pharmaceutical phases. Do pharmaceutical co-crystals represent a new path to improved medicines? Ö Almarsson, MJ Zaworotko Chemical communications, 1889-1896, 2004 | 980 | 2004 |
Pharmaceutical cocrystals: along the path to improved medicines NK Duggirala, ML Perry, Ö Almarsson, MJ Zaworotko Chemical communications 52 (4), 640-655, 2016 | 963 | 2016 |
Crystal engineering of novel cocrystals of a triazole drug with 1, 4-dicarboxylic acids JF Remenar, SL Morissette, ML Peterson, B Moulton, JM MacPhee, ... Journal of the American Chemical Society 125 (28), 8456-8457, 2003 | 802 | 2003 |
Optimization of lipid nanoparticles for intramuscular administration of mRNA vaccines KJ Hassett, KE Benenato, E Jacquinet, A Lee, A Woods, O Yuzhakov, ... Molecular Therapy-Nucleic Acids 15, 1-11, 2019 | 694 | 2019 |
Preclinical and clinical demonstration of immunogenicity by mRNA vaccines against H10N8 and H7N9 influenza viruses K Bahl, JJ Senn, O Yuzhakov, A Bulychev, LA Brito, KJ Hassett, ME Laska, ... Molecular Therapy 25 (6), 1316-1327, 2017 | 693 | 2017 |
A novel amino lipid series for mRNA delivery: improved endosomal escape and sustained pharmacology and safety in non-human primates S Sabnis, ES Kumarasinghe, T Salerno, C Mihai, T Ketova, JJ Senn, ... Molecular Therapy 26 (6), 1509-1519, 2018 | 626 | 2018 |
Performance comparison of a co-crystal of carbamazepine with marketed product MB Hickey, ML Peterson, LA Scoppettuolo, SL Morrisette, A Vetter, ... European journal of pharmaceutics and biopharmaceutics 67 (1), 112-119, 2007 | 498 | 2007 |
Combined use of crystalline salt forms and precipitation inhibitors to improve oral absorption of celecoxib from solid oral formulations HR Guzmán, M Tawa, Z Zhang, P Ratanabanangkoon, P Shaw, ... Journal of pharmaceutical sciences 96 (10), 2686-2702, 2007 | 462 | 2007 |
Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA S Patel, N Ashwanikumar, E Robinson, Y Xia, C Mihai, JP Griffith III, ... Nature communications 11 (1), 983, 2020 | 394 | 2020 |
Elucidation of crystal form diversity of the HIV protease inhibitor ritonavir by high-throughput crystallization SL Morissette, S Soukasene, D Levinson, MJ Cima, Ö Almarsson Proceedings of the National Academy of Sciences 100 (5), 2180-2184, 2003 | 388 | 2003 |
Drugs as materials: valuing physical form in drug discovery CR Gardner, CT Walsh, Ö Almarsson Nature Reviews Drug Discovery 3 (11), 926-934, 2004 | 348 | 2004 |
Impact of lipid nanoparticle size on mRNA vaccine immunogenicity KJ Hassett, J Higgins, A Woods, B Levy, Y Xia, CJ Hsiao, E Acosta, ... Journal of Controlled Release 335, 237-246, 2021 | 240 | 2021 |
Boosting intracellular delivery of lipid nanoparticle-encapsulated mRNA S Patel, N Ashwanikumar, E Robinson, A DuRoss, C Sun, ... Nano letters 17 (9), 5711-5718, 2017 | 222 | 2017 |
Quinoline binding site on malaria pigment crystal: a rational pathway for antimalaria drug design R Buller, ML Peterson, O Almarsson, L Leiserowitz Crystal growth & design 2 (6), 553-562, 2002 | 222 | 2002 |
Iterative high-throughput polymorphism studies on acetaminophen and an experimentally derived structure for form III ML Peterson, SL Morissette, C McNulty, A Goldsweig, P Shaw, ... Journal of the American Chemical Society 124 (37), 10958-10959, 2002 | 213 | 2002 |
Pharmaceutical co-crystal compositions Ö Almarsson, MB Hickey, ML Peterson, MJ Zaworotko, B Moulton, ... US Patent 7,927,613, 2011 | 164 | 2011 |
Expanding the scope of crystal form evaluation in pharmaceutical science ML Peterson, MB Hickey, MJ Zaworotko, Ö Almarsson J. Pharm. Pharm. Sci 9 (3), 317-326, 2006 | 157 | 2006 |
Remarkable activation of enzymes in nonaqueous media by denaturing organic cosolvents Ö Almarsson, AM Klibanov Biotechnology and Bioengineering 49 (1), 87-92, 1996 | 157 | 1996 |
Evaluation of the factors influencing reactivity and stereospecificity in NAD (P) H dependent dehydrogenase enzymes O Almarsson, TC Bruice Journal of the American Chemical Society 115 (6), 2125-2138, 1993 | 141 | 1993 |