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Aleix Lafita
Aleix Lafita
E-mail confirmado em gsk.com
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Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states
M Girbig, AD Misiaszek, MK Vorländer, A Lafita, H Grötsch, F Baudin, ...
Nature structural & molecular biology 28 (2), 210-219, 2021
832021
Automated evaluation of quaternary structures from protein crystals
S Bliven, A Lafita, A Parker, G Capitani, JM Duarte
PLoS computational biology 14 (4), e1006104, 2018
772018
Assessment of protein assembly prediction in CASP12
A Lafita, S Bliven, A Kryshtafovych, M Bertoni, B Monastyrskyy, JM Duarte, ...
Proteins: Structure, Function, and Bioinformatics, 2017
622017
BioJava 5: A community driven open-source bioinformatics library
A Lafita, S Bliven, A Prlić, D Guzenko, PW Rose, A Bradley, P Pavan, ...
PLoS computational biology 15 (2), e1006791, 2019
482019
Cryo-EM structures of human RNA polymerase I
AD Misiaszek, M Girbig, H Grötsch, F Baudin, B Murciano, A Lafita, ...
Nature structural & molecular biology 28 (12), 997-1008, 2021
392021
Assessment of protein assembly prediction in CASP13
D Guzenko, A Lafita, B Monastyrskyy, A Kryshtafovych, JM Duarte
Proteins: Structure, Function, and Bioinformatics 87 (12), 1190-1199, 2019
382019
Tandem domain swapping: determinants of multidomain protein misfolding
A Lafita, P Tian, RB Best, A Bateman
Current Opinion in Structural Biology 58, 97-104, 2019
352019
Analyzing the symmetrical arrangement of structural repeats in proteins with CE-Symm
SE Bliven, A Lafita, PW Rose, G Capitani, A Prlić, PE Bourne
PLoS computational biology 15 (4), e1006842, 2019
292019
Defining the remarkable structural malleability of a bacterial surface protein Rib domain implicated in infection
F Whelan, A Lafita, SC Griffiths, REM Cooper, JL Whittingham, ...
Proceedings of the National Academy of Sciences 116 (52), 26540-26548, 2019
212019
Periscope Proteins are variable-length regulators of bacterial cell surface interactions
F Whelan, A Lafita, J Gilburt, C Dégut, SC Griffiths, HT Jenkins, ...
Proceedings of the National Academy of Sciences 118 (23), e2101349118, 2021
172021
Discovery of fibrillar adhesins across bacterial species
V Monzon, A Lafita, A Bateman
BMC genomics 22, 1-14, 2021
152021
Biological and functional relevance of CASP predictions
T Liu, S Ish‐Shalom, W Torng, A Lafita, C Bock, M Mort, DN Cooper, ...
Proteins: Structure, Function, and Bioinformatics 86, 374-386, 2018
142018
The thrombospondin module 1 domain of the matricellular protein CCN3 shows an atypical disulfide pattern and incomplete CWR layers
ER Xu, A Lafita, A Bateman, M Hyvönen
Acta Crystallographica Section D: Structural Biology 76 (2), 124-134, 2020
92020
TADOSS: computational estimation of tandem domain swap stability
A Lafita, P Tian, RB Best, A Bateman
Bioinformatics 35 (14), 2507-2508, 2019
82019
Predicted mechanistic impacts of human protein missense variants
J Jänes, M Müller, S Selvaraj, D Manoel, J Stephenson, C Gonçalves, ...
bioRxiv, 2024
32024
Domain shuffling of a highly mutable ligand‐binding fold drives adhesin generation across the bacterial kingdom
R Barringer, AE Parnell, A Lafita, V Monzon, CR Back, M Madej, ...
Proteins: Structure, Function, and Bioinformatics 91 (8), 1007-1020, 2023
22023
Modelling structural rearrangements in proteins using Euclidean distance matrices
A Lafita, A Bateman
F1000Research 9, 728, 2020
22020
Assessment of protein assembly prediction in CASP12 & Conformational dynamics of integrin α-l domains
A Lafita
ETH Zurich, 2017
22017
Fine-tuning Protein Language Models with Deep Mutational Scanning improves Variant Effect Prediction
A Lafita, F Gonzalez, M Hossam, P Smyth, J Deasy, A Allyn-Feuer, ...
arXiv preprint arXiv:2405.06729, 2024
12024
Cryo-EM structure of a single-chain β1-adrenoceptor–AmpC β-lactamase fusion protein
G Collu, I Mohammed, A Lafita, T Bierig, E Poghosyan, S Bliven, ...
bioRxiv, 2021.09. 25.461805, 2021
12021
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