| RNA-Guided Human Genome Engineering via Cas9 P Mali, L Yang, KM Esvelt, J Aach, M Guell, JE DiCarlo, JE Norville, ... Science 339 (6121), 823-826, 2013 | 11860 | 2013 |
| CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering P Mali, J Aach, PB Stranges, KM Esvelt, M Moosburner, S Kosuri, L Yang, ... Nature biotechnology 31 (9), 833-838, 2013 | 2345 | 2013 |
| Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems JE DiCarlo, JE Norville, P Mali, X Rios, J Aach, GM Church Nucleic acids research 41 (7), 4336-4343, 2013 | 2071 | 2013 |
| Cas9 as a versatile tool for engineering biology P Mali, KM Esvelt, GM Church Nature Methods 10 (10), 957-963, 2013 | 1775 | 2013 |
| Orthogonal Cas9 proteins for RNA-guided gene regulation and editing KM Esvelt, P Mali, JL Braff, M Moosburner, SJ Yaung, GM Church Nature methods 10 (11), 1116-1121, 2013 | 1110 | 2013 |
| Highly Multiplexed Subcellular RNA Sequencing in Situ JH Lee, ER Daugharthy, J Scheiman, R Kalhor, JL Yang, TC Ferrante, ... Science 343 (6177), 1360-1363, 2014 | 1076 | 2014 |
| A multifunctional AAV-CRISPR-Cas9 and its host response WL Chew, M Tabebordbar, JKW Cheng, P Mali, EY Wu, AHM Ng, K Zhu, ... Nature Methods 13 (10), 868-874, 2016 | 687 | 2016 |
| Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells J Zou, ML Maeder, P Mali, SM Pruett-Miller, S Thibodeau-Beganny, ... Cell Stem Cell 5 (1), 97-110, 2009 | 631 | 2009 |
| Butyrate Greatly Enhances Derivation of Human Induced Pluripotent Stem Cells by Promoting Epigenetic Remodeling and the Expression of Pluripotency‐Associated Genes P Mali, BK Chou, J Yen, Z Ye, J Zou, S Dowey, RA Brodsky, JE Ohm, ... Stem Cells 28 (4), 713-720, 2010 | 579 | 2010 |
| Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures BK Chou, P Mali, X Huang, Z Ye, SN Dowey, LMS Resar, C Zou, ... Cell research 21 (3), 518-529, 2011 | 542 | 2011 |
| Optimization of scarless human stem cell genome editing L Yang, M Guell, S Byrne, JL Yang, A De Los Angeles, P Mali, J Aach, ... Nucleic acids research 41 (19), 9049-9061, 2013 | 507 | 2013 |
| Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders Z Ye, H Zhan, P Mali, S Dowey, DM Williams, YY Jang, CV Dang, ... Blood 114 (27), 5473-5480, 2009 | 476 | 2009 |
| Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach. R Chari, P Mali, M Moosburner, GM Church Nature methods, 2015 | 459 | 2015 |
| Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions A Swistowski, J Peng, Q Liu, P Mali, MS Rao, L Cheng, X Zeng Stem Cells 28 (10), 1893-1904, 2010 | 396 | 2010 |
| Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease J Zou, P Mali, X Huang, SN Dowey, L Cheng Blood 118 (17), 4599-4608, 2011 | 394 | 2011 |
| Combinatorial CRISPR–Cas9 screens for de novo mapping of genetic interactions JP Shen, D Zhao, R Sasik, J Luebeck, A Birmingham, ... Nature Methods 14, 573-576, 2017 | 388 | 2017 |
| Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts P Mali, Z Ye, HH Hommond, X Yu, J Lin, G Chen, J Zou, L Cheng Stem Cells 26 (8), 1998-2005, 2008 | 367 | 2008 |
| Developmental barcoding of whole mouse via homing CRISPR R Kalhor, K Kalhor, L Mejia, K Leeper, A Graveline, P Mali, GM Church Science 361 (6405), eaat9804, 2018 | 340 | 2018 |
| Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers AW Briggs, X Rios, R Chari, L Yang, F Zhang, P Mali, GM Church Nucleic acids research 40 (15), e117-e117, 2012 | 297 | 2012 |
| Self-organized vascular networks from human pluripotent stem cells in a synthetic matrix S Kusuma, YI Shen, D Hanjaya-Putra, P Mali, L Cheng, S Gerecht Proceedings of the National Academy of Sciences 110 (31), 12601-12606, 2013 | 277 | 2013 |
George ChurchHarvard Medical SchoolE-mail confirmado em harvard.edu
