| The FAIR Guiding Principles for scientific data management and stewardship Scientific Data 3, 160018, 2016 | 14945* | 2016 |
| Transcriptome and genome sequencing uncovers functional variation in humans T Lappalainen, M Sammeth, MR Friedländer, PAC ‘t Hoen, J Monlong, ... Nature 501 (7468), 506-511, 2013 | 2114 | 2013 |
| Systematic identification of trans eQTLs as putative drivers of known disease associations HJ Westra, MJ Peters, T Esko, H Yaghootkar, C Schurmann, J Kettunen, ... Nature genetics 45 (10), 1238-1243, 2013 | 1942 | 2013 |
| A promoter-level mammalian expression atlas Nature 507 (7493), 462-470, 2014 | 1772 | 2014 |
| Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... Nature genetics 53 (9), 1300-1310, 2021 | 1049 | 2021 |
| Gateways to the FANTOM5 promoter level mammalian expression atlas M Lizio, J Harshbarger, H Shimoji, J Severin, T Kasukawa, S Sahin, ... Genome biology 16, 1-14, 2015 | 892 | 2015 |
| Deep sequencing-based expression analysis shows major advances in robustness, resolution and inter-lab portability over five microarray platforms PAC 't Hoen, Y Ariyurek, HH Thygesen, E Vreugdenhil, RHAM Vossen, ... Nucleic acids research 36 (21), e141-e141, 2008 | 784 | 2008 |
| Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions ENM Nolte-’t Hoen, HPJ Buermans, M Waasdorp, W Stoorvogel, ... Nucleic acids research 40 (18), 9272-9285, 2012 | 624 | 2012 |
| Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... BioRxiv, 447367, 2018 | 511 | 2018 |
| Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure LV Wain, GC Verwoert, PF O'reilly, G Shi, T Johnson, AD Johnson, ... Nature genetics 43 (10), 1005-1011, 2011 | 509 | 2011 |
| Disease variants alter transcription factor levels and methylation of their binding sites MJ Bonder, R Luijk, DV Zhernakova, M Moed, P Deelen, M Vermaat, ... Nature genetics 49 (1), 131-138, 2017 | 477 | 2017 |
| Identification of context-dependent expression quantitative trait loci in whole blood DV Zhernakova, P Deelen, M Vermaat, M Van Iterson, M Van Galen, ... Nature genetics 49 (1), 139-145, 2017 | 463 | 2017 |
| Alternative mRNA transcription, processing, and translation: insights from RNA sequencing E de Klerk, P AC‘t Hoen Trends in Genetics 31 (3), 128-139, 2015 | 427 | 2015 |
| Genetic and environmental influences interact with age and sex in shaping the human methylome J Van Dongen, MG Nivard, G Willemsen, JJ Hottenga, Q Helmer, ... Nature communications 7 (1), 11115, 2016 | 375 | 2016 |
| Effect of predicted protein-truncating genetic variants on the human transcriptome MA Rivas, M Pirinen, DF Conrad, M Lek, EK Tsang, KJ Karczewski, ... Science 348 (6235), 666-669, 2015 | 362 | 2015 |
| Andra Waagmeester, Peter Wittenburg, Katherine Wolstencroft, Jun Zhao, and Barend Mons MD Wilkinson, M Dumontier, IJJ Aalbersberg, G Appleton, M Axton, ... The FAIR Guiding Principles for scientific data management and stewardship …, 2016 | 313 | 2016 |
| Reproducibility of high-throughput mRNA and small RNA sequencing across laboratories PAC 't Hoen, MR Friedländer, J Almlöf, M Sammeth, I Pulyakhina, ... Nature biotechnology 31 (11), 1015-1022, 2013 | 276 | 2013 |
| Prorenin induces intracellular signaling in cardiomyocytes independently of angiotensin II JJ Saris, PAC ’t Hoen, IM Garrelds, DHW Dekkers, JT den Dunnen, ... Hypertension 48 (4), 564-571, 2006 | 273 | 2006 |
| Guidelines for antisense oligonucleotide design and insight into splice-modulating mechanisms A Aartsma-Rus, L Van Vliet, M Hirschi, AAM Janson, H Heemskerk, ... Molecular Therapy 17 (3), 548-553, 2009 | 240 | 2009 |
| Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer M Van den Boogaard, LYE Wong, F Tessadori, ML Bakker, ... The Journal of clinical investigation 122 (7), 2519-2530, 2012 | 222 | 2012 |
