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Arwen W. Gao
Arwen W. Gao
Assistant Professor, Amsterdam UMC - Location AMC
E-mail confirmado em amsterdamumc.nl
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Mitochondrial response to nutrient availability and its role in metabolic disease
AW Gao, C Cantó, RH Houtkooper
EMBO molecular medicine 6 (5), 580-589, 2014
1602014
Mfn1 deficiency in the liver protects against diet-induced insulin resistance and enhances the hypoglycemic effect of metformin
SS Kulkarni, M Joffraud, M Boutant, J Ratajczak, AW Gao, C Maclachlan, ...
Diabetes 65 (12), 3552-3560, 2016
892016
A sensitive mass spectrometry platform identifies metabolic changes of life history traits in C. elegans
AW Gao, IA Chatzispyrou, R Kamble, YJ Liu, K Herzog, RL Smith, ...
Scientific reports 7 (1), 2408, 2017
782017
Identification of key pathways and metabolic fingerprints of longevity in C. elegans
AW Gao, RL Smith, M Van Weeghel, R Kamble, GE Janssens, ...
Experimental gerontology 113, 128-140, 2018
772018
Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion
YJ Liu, GE Janssens, RL McIntyre, M Molenaars, R Kamble, AW Gao, ...
PLoS genetics 15 (3), e1007633, 2019
712019
The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress
TY Li, MB Sleiman, H Li, AW Gao, A Mottis, AM Bachmann, GE Alam, X Li, ...
Nature aging 1 (2), 165-178, 2021
622021
Metabolomics and lipidomics in Caenorhabditis elegans using a single-sample preparation
M Molenaars, BV Schomakers, HL Elfrink, AW Gao, MAT Vervaart, ...
Disease models & mechanisms 14 (4), dmm047746, 2021
452021
Identifying gene function and module connections by the integration of multispecies expression compendia
H Li, D Rukina, FPA David, TY Li, CM Oh, AW Gao, E Katsyuba, ...
Genome Research 29 (12), 2034-2045, 2019
412019
Natural genetic variation in C. elegans identified genomic loci controlling metabolite levels
AW Gao, MG Sterken, J uit de Bos, J van Creij, R Kamble, BL Snoek, ...
Genome research 28 (9), 1296-1308, 2018
38*2018
Sex-and age-dependent genetics of longevity in a heterogeneous mouse population
M Bou Sleiman, S Roy, AW Gao, MC Sadler, GVG von Alvensleben, H Li, ...
Science 377 (6614), eabo3191, 2022
372022
Modeling Meets Metabolomics—The WormJam Consensus Model as Basis for Metabolic Studies in the Model Organism Caenorhabditis elegans
M Witting, J Hastings, N Rodriguez, CJ Joshi, JPN Hattwell, PR Ebert, ...
Frontiers in molecular biosciences 5, 96, 2018
362018
Forward and reverse genetics approaches to uncover metabolic aging pathways in Caenorhabditis elegans
AW Gao, J uit de Bos, MG Sterken, JE Kammenga, RL Smith, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (9 …, 2018
272018
Mitochondrial fission: firing up mitochondria in brown adipose tissue
AW Gao, RH Houtkooper
The EMBO journal 33 (5), 401-402, 2014
262014
Lysosomes mediate the mitochondrial UPR via mTORC1-dependent ATF4 phosphorylation
TY Li, Q Wang, AW Gao, X Li, Y Sun, A Mottis, M Shong, J Auwerx
Cell Discovery 9 (1), 92, 2023
152023
Anti-retroviral treatment with zidovudine alters pyrimidine metabolism, reduces translation, and extends healthy longevity via ATF-4
RL McIntyre, M Molenaars, BV Schomakers, AW Gao, R Kamble, ...
Cell reports 42 (1), 2023
142023
Multi-omics analysis identifies essential regulators of mitochondrial stress response in two wild-type C. elegans strains
AW Gao, G El Alam, A Lalou, TY Li, M Molenaars, Y Zhu, KA Overmyer, ...
Iscience 25 (2), 2022
102022
V-ATPase/TORC1-mediated ATFS-1 translation directs mitochondrial UPR activation in C. elegans
TY Li, AW Gao, X Li, H Li, YJ Liu, A Lalou, N Neelagandan, F Naef, ...
Journal of Cell Biology 222 (1), e202205045, 2022
82022
Multi-omics analysis identifies essential regulators of mitochondrial stress response in two wild-type C. elegans strains. iScience 25, 103734
AW Gao, G El Alam, A Lalou, TY Li, M Molenaars, Y Zhu, KA Overmyer, ...
82022
Reduced ech-6 expression attenuates fat-induced lifespan shortening in C. elegans
YJ Liu, AW Gao, RL Smith, GE Janssens, DM Panneman, A Jongejan, ...
Scientific reports 12 (1), 3350, 2022
52022
Mass Spectrometry-Based Multi-omics Integration with a Single Set of C. elegans Samples
Y Zhu, A Jen, KA Overmyer, AW Gao, E Shishkova, J Auwerx, JJ Coon
Analytical Chemistry 95 (29), 10930-10938, 2023
42023
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Artigos 1–20