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M. Nicolas Cruz Bournazou
M. Nicolas Cruz Bournazou
KIWI-biolab, Chair of Bioprocess Engineering Technical University Berlin
E-mail confirmado em mailbox.tu-berlin.de - Página inicial
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Bioprocessing in the digital age: the role of process models
H Narayanan, MF Luna, M von Stosch, MN Cruz Bournazou, G Polotti, ...
Biotechnology journal 15 (1), 1900172, 2020
2172020
Consistent development of bioprocesses from microliter cultures to the industrial scale
P Neubauer, MN Cruz Bournazou, F Glauche, S Junne, A Knepper, ...
Engineering in Life Sciences 13 (3), 224-238, 2013
1342013
Model based optimization of the intermittent aeration profile for SBRs under partial nitrification
MN Cruz Bournazou, K Hooshiar, H Arellano-Garcia, G Wozny, ...
Water research 47 (10), 3399-3410, 2013
1082013
Online optimal experimental re‐design in robotic parallel fed‐batch cultivation facilities
MN Cruz Bournazou, T Barz, DC Nickel, D Lopez Cárdenas, F Glauche, ...
Biotechnology and Bioengineering, 2017
962017
Model-based tools for optimal experiments in bioprocess engineering
V Abt, T Barz, MN Cruz Bournazou, C Herwig, P Kroll, J Möller, R Pörtner, ...
Current opinion in chemical engineering 22, 244-252, 2018
812018
Modelling overflow metabolism in Escherichia coli by acetate cycling
E Anane, DC Lopez Cardenas, P Neubauer, MN Cruz Bournazou
Biochemical Engineering Journal, 2017
702017
Continuous Biomanufacturing: Innovative Technologies and Methods
G Subramanian
John Wiley & Sons, 2017
602017
Integrated Robotic Mini Bioreactor Platform for Automated, Parallel Microbial Cultivation With Online Data Handling and Process Control
B Haby, S Hans, E Anane, A Sawatzki, N Krausch, P Neubauer, ...
SLAS TECHNOLOGY: Translating Life Sciences Innovation 24 (6), 569-582, 2019
492019
A model‐based framework for parallel scale‐down fed‐batch cultivations in mini‐bioreactors for accelerated phenotyping
E Anane, ÁC García, B Haby, S Hans, N Krausch, M Krewinkel, ...
Biotechnology and bioengineering 116 (11), 2906-2918, 2019
492019
Anaerobic Digestion Model (AM2) for the Description of Biogas Processes at Dynamic Feedstock Loading Rates
JA Arzate, M Kirstein, FC Ertem, E Kielhorn, H Ramirez Malule, ...
Chemie Ingenieur Technik 89 (5), 686-695, 2017
452017
Online bioprocess data generation, analysis and optimization for parallel fed‐batch fermentations at mL scale
DB Nickel, MN Cruz Bournazou, T Wilms, P Neubauer, A Knepper
Engineering in Life Sciences, 2016
43*2016
Modelling concentration gradients in fed‐batch cultivations of E. coli – towards the flexible design of scale‐down experiments
E Anane, A Sawatzki, P Neubauer, MN Cruz‐Bournazou
Journal of Chemical Technology & Biotechnology 94 (2), 516-526, 2019
412019
Monte Carlo simulations for the analysis of nonlinear parameter confidence intervals in Optimal Experimental Design
N Krausch, T Barz, A Sawatzki, M Gruber, S Kamel, P Neubauer, ...
Frontiers in Bioengineering and Biotechnology 7, 122, 2019
412019
Knowledge transfer across cell lines using hybrid Gaussian process models with entity embedding vectors
C Hutter, M von Stosch, MN Cruz Bournazou, A Butté
Biotechnology and Bioengineering 118 (11), 4389-4401, 2021
382021
Immobilization of thermostable nucleoside phosphorylases on MagReSyn® epoxide microspheres and their application for the synthesis of 2, 6-dihalogenated purine nucleosides
X Zhou, IA Mikhailopulo, MN Cruz Bournazou, P Neubauer
Journal of Molecular Catalysis B: Enzymatic 115, 119-127, 2015
362015
Experimental analysis and numerical modeling of a shell and tube heat storage unit with phase change materials
T Barz, C Zauner, D Lager, DC López Cárdenas, F Hengstberger, ...
Industrial & Engineering Chemistry Research 55 (29), 8154-8164, 2016
332016
Output uncertainty of dynamic growth models: Effect of uncertain parameter estimates on model reliability
E Anane, T Barz, G Sin, KV Gernaey, P Neubauer, MNC Bournazou
Biochemical engineering journal 150, 107247, 2019
312019
Dynamic Model Reduction for Two-Stage Anaerobic Digestion Processes
CK Zhaoyang Duan, Mariano Nicolas Cruz Bournazou
Chemical Engineering Journal, 2017
312017
Design of Experiments based high‐throughput strategy for development and optimization of efficient cell disruption protocols
F Glauche, M Pilarek, MN Cruz Bournazou, P Grunzel, P Neubauer
Engineering in Life Sciences, 2016
312016
Accelerated Bioprocess Development of Endopolygalacturonase-Production with Saccharomyces cerevisiae Using Multivariate Prediction in a 48 Mini-Bioreactor Automated Platform
A Sawatzki, S Hans, H Narayanan, B Haby, N Krausch, M Sokolov, ...
Preprints, 2018
302018
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