| Fibroblast heterogeneity and immunosuppressive environment in human breast cancer A Costa, Y Kieffer, A Scholer-Dahirel, F Pelon, B Bourachot, M Cardon, ... Cancer cell 33 (3), 463-479. e10, 2018 | 1484 | 2018 |
| Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v. 3.0 L Heirendt, S Arreckx, T Pfau, SN Mendoza, A Richelle, A Heinken, ... Nature protocols 14 (3), 639-702, 2019 | 1208 | 2019 |
| Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio I Kuperstein, K Broersen, I Benilova, J Rozenski, W Jonckheere, ... The EMBO journal 29 (19), 3408-3420, 2010 | 664 | 2010 |
| Lipids revert inert Aβ amyloid fibrils to neurotoxic protofibrils that affect learning in mice IC Martins, I Kuperstein, H Wilkinson, E Maes, M Vanbrabant, ... The EMBO journal 27 (1), 224-233, 2008 | 405 | 2008 |
| The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease A Noronha, J Modamio, Y Jarosz, E Guerard, N Sompairac, G Preciat, ... Nucleic acids research 47 (D1), D614-D624, 2019 | 360 | 2019 |
| COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms M Ostaszewski, A Mazein, ME Gillespie, I Kuperstein, A Niarakis, ... Scientific data 7 (1), 136, 2020 | 155 | 2020 |
| Atlas of Cancer Signalling Network: a systems biology resource for integrative analysis of cancer data with Google Maps I Kuperstein, E Bonnet, HA Nguyen, D Cohen, E Viara, L Grieco, ... Oncogenesis 4 (7), e160-e160, 2015 | 150 | 2015 |
| Concomitant Notch activation and p53 deletion trigger epithelial-to-mesenchymal transition and metastasis in mouse gut M Chanrion, I Kuperstein, C Barrière, F El Marjou, D Cohen, D Vignjevic, ... Nature communications 5 (1), 5005, 2014 | 144 | 2014 |
| COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms M Ostaszewski, A Niarakis, A Mazein, I Kuperstein, R Phair, ... Molecular systems biology 17 (10), e10387, 2021 | 100 | 2021 |
| Systems medicine disease maps: community-driven comprehensive representation of disease mechanisms A Mazein, M Ostaszewski, I Kuperstein, S Watterson, N Le Novère, ... NPJ systems biology and applications 4 (1), 21, 2018 | 100 | 2018 |
| Altered expression of key dopaminergic regulatory proteins in the postnatal brain following perinatal n‐3 fatty acid dietary deficiency F Kuperstein, R Eilam, E Yavin Journal of neurochemistry 106 (2), 662-671, 2008 | 94 | 2008 |
| ERK activation and nuclear translocation in amyloid‐β peptide‐and iron‐stressed neuronal cell cultures F Kuperstein, E Yavin European Journal of Neuroscience 16 (1), 44-54, 2002 | 76 | 2002 |
| NaviCell: a web-based environment for navigation, curation and maintenance of large molecular interaction maps I Kuperstein, DPA Cohen, S Pook, E Viara, L Calzone, E Barillot, ... BMC systems biology 7, 1-13, 2013 | 72 | 2013 |
| Overexpression of dopamine receptor genes and their products in the postnatal rat brain following maternal n‐3 fatty acid dietary deficiency F Kuperstein, E Yakubov, P Dinerman, S Gil, R Eylam, N Salem Jr, ... Journal of neurochemistry 95 (6), 1550-1562, 2005 | 70 | 2005 |
| Community-driven roadmap for integrated disease maps M Ostaszewski, S Gebel, I Kuperstein, A Mazein, A Zinovyev, U Dogrusoz, ... Briefings in bioinformatics 20 (2), 659-670, 2019 | 68 | 2019 |
| Differential role of specific PKC isoforms in the proliferation of glial cells and the expression of the astrocytic markers GFAP and glutamine synthetase C Brodie, I Kuperstein, P Acs, PM Blumberg Molecular brain research 56 (1-2), 108-117, 1998 | 60 | 1998 |
| Pro‐apoptotic signaling in neuronal cells following iron and amyloid beta peptide neurotoxicity F Kuperstein, E Yavin Journal of neurochemistry 86 (1), 114-125, 2003 | 56 | 2003 |
| A multiscale signalling network map of innate immune response in cancer reveals cell heterogeneity signatures M Kondratova, U Czerwinska, N Sompairac, SD Amigorena, V Soumelis, ... Nature communications 10 (1), 4808, 2019 | 45 | 2019 |
| The shortest path is not the one you know: application of biological network resources in precision oncology research I Kuperstein, L Grieco, DPA Cohen, D Thieffry, A Zinovyev, E Barillot Mutagenesis 30 (2), 191-204, 2015 | 45 | 2015 |
| Drug-driven synthetic lethality: bypassing tumor cell genetics with a combination of AsiDNA and PARP inhibitors W Jdey, S Thierry, C Russo, F Devun, M Al Abo, P Noguiez-Hellin, JS Sun, ... Clinical Cancer Research 23 (4), 1001-1011, 2017 | 41 | 2017 |
Andrei ZinovyevIn silico R&D EvotecE-mail confirmado em evotec.com