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David Picketts
David Picketts
Senior Scientist, Ottawa Hospital Research Institute
E-mail confirmado em ohri.ca
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Mutations in a putative global transcriptional regulator cause X-linked mental retardation with α-thalassemia (ATR-X syndrome)
RJ Gibbons, DJ Picketts, L Villard, DR Higgs
Cell 80 (6), 837-845, 1995
7281995
ATRX encodes a novel member of the SNF2 family of proteins: mutations point to a common mechanism underlying the ATR-X syndrome
DJ Picketts, DR Higgs, S Bachoo, DJ Blake, OWJ Quarrell, RJ Gibbons
Human molecular genetics 5 (12), 1899-1907, 1996
3131996
Localization of a putative transcriptional regulator (ATRX) at pericentromeric heterochromatin and the short arms of acrocentric chromosomes
TL McDowell, RJ Gibbons, H Sutherland, DM O’Rourke, WA Bickmore, ...
Proceedings of the National Academy of Sciences 96 (24), 13983-13988, 1999
3051999
ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
S Iwase, B Xiang, S Ghosh, T Ren, PW Lewis, JC Cochrane, CD Allis, ...
Nature structural & molecular biology 18 (7), 769-776, 2011
3002011
Inhibitor of apoptosis protein cIAP2 is essential for lipopolysaccharide-induced macrophage survival
D Conte, M Holcik, CA Lefebvre, E LaCasse, DJ Picketts, KE Wright, ...
Molecular and cellular biology 26 (2), 699-708, 2006
2472006
The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis
NG Bérubé, M Mangelsdorf, M Jagla, J Vanderluit, D Garrick, RJ Gibbons, ...
The Journal of clinical investigation 115 (2), 258-267, 2005
2442005
Isolation of human NURF: a regulator of Engrailed gene expression
O Barak, MA Lazzaro, WS Lane, DW Speicher, DJ Picketts, R Shiekhattar
The EMBO journal 22 (22), 6089-6100, 2003
2442003
A novel transcription regulatory complex containing death domain-associated protein and the ATR-X syndrome protein
J Tang, S Wu, H Liu, R Stratt, OG Barak, R Shiekhattar, DJ Picketts, ...
Journal of Biological Chemistry 279 (19), 20369-20377, 2004
2342004
Mutations in transcriptional regulator ATRX establish the functional significance of a PHD-like domain
RJ Gibbons, S Bachoo, DJ Picketts, S Aftimos, B Asenbauer, JA Bergoffen, ...
Nature genetics 17 (2), 146-148, 1997
2341997
Cell cycle-dependent phosphorylation of the ATRX protein correlates with changes in nuclear matrix and chromatin association
NG Bérubé, CA Smeenk, DJ Picketts
Human molecular genetics 9 (4), 539-547, 2000
1822000
Cloning and characterization of the murine Imitation Switch (ISWI) genes: differential expression patterns suggest distinct developmental roles for Snf2h and Snf2l
MA Lazzaro, DJ Picketts
Journal of neurochemistry 77 (4), 1145-1156, 2001
1372001
Molecular cloning of a Chinese hamster mitochondrial protein related to the “chaperonin” family of bacterial and plant proteins
DJ Picketts, CS Mayanil, RS Gupta
Journal of Biological Chemistry 264 (20), 12001-12008, 1989
1161989
PHF6 interacts with the nucleosome remodeling and deacetylation (NuRD) complex
MAM Todd, DJ Picketts
Journal of proteome research 11 (8), 4326-4337, 2012
1102012
Stalled replication forks within heterochromatin require ATRX for protection
MS Huh, D Ivanochko, LE Hashem, M Curtin, M Delorme, E Goodall, ...
Cell death & disease 7 (5), e2220-e2220, 2016
982016
Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation
M Alvarez-Saavedra, Y De Repentigny, PS Lagali, EVS Raghu Ram, ...
Nature communications 5 (1), 4181, 2014
882014
Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling
C Danussi, P Bose, PT Parthasarathy, PC Silberman, JS Van Arnam, ...
Nature communications 9 (1), 1057, 2018
862018
Comparison of the human and murine ATRX gene identifies highly conserved, functionally important domains
DJ Picketts, AO Tastan, DR Higgs, RJ Gibbons
Mammalian genome 9 (5), 400-403, 1998
841998
Snf2l regulates Foxg1-dependent progenitor cell expansion in the developing brain
DJ Yip, CP Corcoran, M Alvarez-Saavedra, A DeMaria, S Rennick, ...
Developmental cell 22 (4), 871-878, 2012
812012
Neurodevelopmental defects resulting from ATRX overexpression in transgenic mice
NG Bérubé, M Jagla, C Smeenk, Y De Repentigny, R Kothary, DJ Picketts
Human molecular genetics 11 (3), 253-261, 2002
812002
The role of ISWI chromatin remodeling complexes in brain development and neurodevelopmental disorders
LR Goodwin, DJ Picketts
Molecular and Cellular Neuroscience 87, 55-64, 2018
712018
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Artigos 1–20