| β-Peptides: from structure to function RP Cheng, SH Gellman, WF DeGrado Chemical reviews 101 (10), 3219-3232, 2001 | 2270 | 2001 |
| A thermodynamic scale for the helix-forming tendencies of the commonly occurring amino acids KT O'Neil, WF DeGrado Science 250 (4981), 646-651, 1990 | 1512 | 1990 |
| How calmodulin binds its targets: sequence independent recognition of amphiphilic α-helices KT O'Neil, WF DeGrado Trends in biochemical sciences 15 (2), 59-64, 1990 | 1018 | 1990 |
| Foldamers as versatile frameworks for the design and evolution of function CM Goodman, S Choi, S Shandler, WF DeGrado Nature chemical biology 3 (5), 252-262, 2007 | 952 | 2007 |
| Characterization of a helical protein designed from first principles L Regan, WF DeGrado Science 241 (4868), 976-978, 1988 | 765 | 1988 |
| Protein design: a hierarchic approach JW Bryson, SF Betz, HS Lu, DJ Suich, HX Zhou, KT O'Neil, WF DeGrado Science 270 (5238), 935-941, 1995 | 739 | 1995 |
| De novo design and structural characterization of proteins and metalloproteins WF DeGrado, CM Summa, V Pavone, F Nastri, A Lombardi Annual review of biochemistry 68 (1), 779-819, 1999 | 738 | 1999 |
| Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers SD Cady, K Schmidt-Rohr, J Wang, CS Soto, WF DeGrado, M Hong Nature 463 (7281), 689-692, 2010 | 727 | 2010 |
| Structural basis for the function and inhibition of an influenza virus proton channel AL Stouffer, R Acharya, D Salom, AS Levine, L Di Costanzo, CS Soto, ... Nature 451 (7178), 596-599, 2008 | 711 | 2008 |
| Synthetic amphiphilic peptide models for protein ion channels JD Lear, ZR Wasserman, WF DeGrado Science 240 (4856), 1177-1181, 1988 | 705 | 1988 |
| Protein design, a minimalist approach WF DeGrado, ZR Wasserman, JD Lear Science 243 (4891), 622-628, 1989 | 679 | 1989 |
| De novo design of antimicrobial polymers, foldamers, and small molecules: from discovery to practical applications GN Tew, RW Scott, ML Klein, WF DeGrado Accounts of chemical research 43 (1), 30-39, 2010 | 635 | 2010 |
| Short peptides self-assemble to produce catalytic amyloids CM Rufo, YS Moroz, OV Moroz, J Stöhr, TA Smith, X Hu, WF DeGrado, ... Nature chemistry 6 (4), 303-309, 2014 | 602 | 2014 |
| Design and synthesis of multi-haem proteins DE Robertson, RS Farid, CC Moser, JL Urbauer, SE Mulholland, R Pidikiti, ... Nature 368 (6470), 425-432, 1994 | 598 | 1994 |
| De novo design of biomimetic antimicrobial polymers GN Tew, D Liu, B Chen, RJ Doerksen, J Kaplan, PJ Carroll, ML Klein, ... Proceedings of the National Academy of Sciences 99 (8), 5110-5114, 2002 | 586 | 2002 |
| Amphiphilic polymethacrylate derivatives as antimicrobial agents K Kuroda, WF DeGrado Journal of the American Chemical Society 127 (12), 4128-4129, 2005 | 585 | 2005 |
| Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifs A Senes, DE Engel, WF DeGrado Current opinion in structural biology 14 (4), 465-479, 2004 | 539 | 2004 |
| Induction of peptide conformation at apolar water interfaces. 1. A study with model peptides of defined hydrophobic periodicity WF DeGrado, JD Lear Journal of the American Chemical Society 107 (25), 7684-7689, 1985 | 518 | 1985 |
| De novo design of antibacterial β-peptides Y Hamuro, JP Schneider, WF DeGrado Journal of the American Chemical Society 121 (51), 12200-12201, 1999 | 504 | 1999 |
| Asparagine-mediated self-association of a model transmembrane helix C Choma, H Gratkowski, JD Lear, WF DeGrado Nature structural biology 7 (2), 161-166, 2000 | 484 | 2000 |