Restoring cystic fibrosis transmembrane conductance regulator function reduces airway bacteria and inflammation in people with cystic fibrosis and chronic lung infections KB Hisert, SL Heltshe, C Pope, P Jorth, X Wu, RM Edwards, M Radey, ... American journal of respiratory and critical care medicine 195 (12), 1617-1628, 2017 | 358 | 2017 |
Regional isolation drives bacterial diversification within cystic fibrosis lungs P Jorth, BJ Staudinger, X Wu, KB Hisert, H Hayden, J Garudathri, ... Cell host & microbe 18 (3), 307-319, 2015 | 333 | 2015 |
Probing proteomes using capillary isoelectric focusing-electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry PK Jensen, L Paša-Tolić, GA Anderson, JA Horner, MS Lipton, JE Bruce, ... Analytical chemistry 71 (11), 2076-2084, 1999 | 321 | 1999 |
Normalization of NAD+ Redox Balance as a Therapy for Heart Failure CF Lee, JD Chavez, L Garcia-Menendez, Y Choi, ND Roe, YA Chiao, ... Circulation 134 (12), 883-894, 2016 | 320 | 2016 |
High throughput proteome-wide precision measurements of protein expression using mass spectrometry L Pasa-Tolic, PK Jensen, GA Anderson, MS Lipton, KK Peden, ... Journal of the American Chemical Society 121 (34), 1999 | 279 | 1999 |
Mass spectrometry identifiable cross-linking strategy for studying protein− protein interactions X Tang, GR Munske, WF Siems, JE Bruce Analytical chemistry 77 (1), 311-318, 2005 | 276 | 2005 |
High-resolution accurate mass measurements of biomolecules using a new electrospray ionization ion cyclotron resonance mass spectrometer BE Winger, SA Hofstadler, JE Bruce, HR Udseth, RD Smith Journal of the American Society for Mass Spectrometry 4 (7), 566-577, 1993 | 273 | 1993 |
Using electrospray ionization FTICR mass spectrometry to study competitive binding of inhibitors to carbonic anhydrase X Cheng, R Chen, JE Bruce, BL Schwartz, GA Anderson, SA Hofstadler, ... Journal of the American Chemical Society 117 (34), 8859-8860, 1995 | 244 | 1995 |
New mass spectrometric methods for the study of noncovalent associations of biopolymers Q PaulaáLei Chemical Society Reviews 26 (3), 191-202, 1997 | 228 | 1997 |
Isotope distribution encoded tags for protein identification DR Goodlett, JE Bruce, B Rist, RD Smith, R Aebersold US Patent 6,629,040, 2003 | 211 | 2003 |
Screening derivatized peptide libraries for tight binding inhibitors to carbonic anhydrase II by electrospray ionization-mass spectrometry J Gao, X Cheng, R Chen, GB Sigal, JE Bruce, BL Schwartz, SA Hofstadler, ... Journal of medicinal chemistry 39 (10), 1949-1955, 1996 | 201 | 1996 |
Mitochondrial protein interactome elucidated by chemical cross-linking mass spectrometry DK Schweppe, JD Chavez, CF Lee, A Caudal, SE Kruse, R Stuppard, ... Proceedings of the National Academy of Sciences 114 (7), 1732-1737, 2017 | 200 | 2017 |
Identification of protein-protein interactions and topologies in living cells with chemical cross-linking and mass spectrometry H Zhang, X Tang, GR Munske, N Tolic, GA Anderson, JE Bruce Molecular & Cellular Proteomics 8 (3), 409-420, 2009 | 191 | 2009 |
Protein identification with a single accurate mass of a cysteine-containing peptide and constrained database searching DR Goodlett, JE Bruce, GA Anderson, B Rist, L Pasa-Tolic, O Fiehn, ... Analytical chemistry 72 (6), 1112-1118, 2000 | 185 | 2000 |
Towards a structurally resolved human protein interaction network DF Burke, P Bryant, I Barrio-Hernandez, D Memon, G Pozzati, A Shenoy, ... Nature Structural & Molecular Biology 30 (2), 216-225, 2023 | 173 | 2023 |
A new cross-linking strategy: protein interaction reporter (PIR) technology for protein–protein interaction studies X Tang, JE Bruce Molecular biosystems 6 (6), 939-947, 2010 | 173 | 2010 |
Dissociation of tetrameric ions of noncovalent streptavidin complexes formed by electrospray ionization BL Schwartz, JE Bruce, GA Anderson, SA Hofstadler, AL Rockwood, ... Journal of the American Society for Mass Spectrometry 6 (6), 459-465, 1995 | 166 | 1995 |
Accurate mass multiplexed tandem mass spectrometry for high-throughput polypeptide identification from mixtures C Masselon, GA Anderson, R Harkewicz, JE Bruce, L Pasa-Tolic, ... Analytical chemistry 72 (8), 1918-1924, 2000 | 152 | 2000 |
Host-microbe protein interactions during bacterial infection DK Schweppe, C Harding, JD Chavez, X Wu, E Ramage, PK Singh, ... Chemistry & biology 22 (11), 1521-1530, 2015 | 151 | 2015 |
Chemical cross-linking with mass spectrometry: a tool for systems structural biology JD Chavez, JE Bruce Current opinion in chemical biology 48, 8-18, 2019 | 149 | 2019 |