Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts J Paggetti, F Haderk, M Seiffert, B Janji, U Distler, W Ammerlaan, YJ Kim, ... Blood, The Journal of the American Society of Hematology 126 (9), 1106-1117, 2015 | 502 | 2015 |
Human signal-regulatory protein is expressed on normal, but not on subsets of leukemic myeloid cells and mediates cellular adhesion involving its counterreceptor CD47 M Seiffert, C Cant, Z Chen, I Rappold, W Brugger, L Kanz, EJ Brown, ... Blood, The Journal of the American Society of Hematology 94 (11), 3633-3643, 1999 | 384 | 1999 |
IL4I1 is a metabolic immune checkpoint that activates the AHR and promotes tumor progression A Sadik, LFS Patterson, S Öztürk, SR Mohapatra, V Panitz, PF Secker, ... Cell 182 (5), 1252-1270. e34, 2020 | 383 | 2020 |
Tumor-derived exosomes modulate PD-L1 expression in monocytes F Haderk, R Schulz, M Iskar, LL Cid, T Worst, KV Willmund, A Schulz, ... Science immunology 2 (13), eaah5509, 2017 | 305 | 2017 |
miRNA-130a targets ATG2B and DICER1 to inhibit autophagy and trigger killing of chronic lymphocytic leukemia cells V Kovaleva, R Mora, YJ Park, C Plass, AI Chiramel, R Bartenschlager, ... Cancer research 72 (7), 1763-1772, 2012 | 244 | 2012 |
PD-L1 checkpoint blockade prevents immune dysfunction and leukemia development in a mouse model of chronic lymphocytic leukemia F McClanahan, B Hanna, S Miller, AJ Clear, P Lichter, JG Gribben, ... Blood, The Journal of the American Society of Hematology 126 (2), 203-211, 2015 | 224 | 2015 |
Signal-regulatory protein α (SIRPα) but not SIRPβ is involved in T-cell activation, binds to CD47 with high affinity, and is expressed on immature CD34+ CD38− hematopoietic cells M Seiffert, P Brossart, C Cant, M Cella, M Colonna, W Brugger, L Kanz, ... Blood, The Journal of the American Society of Hematology 97 (9), 2741-2749, 2001 | 223 | 2001 |
Cutting edge: signal-regulatory protein β1 is a DAP12-associated activating receptor expressed in myeloid cells J Dietrich, M Cella, M Seiffert, HJ Bühring, M Colonna The Journal of Immunology 164 (1), 9-12, 2000 | 203 | 2000 |
The basophil activation marker defined by antibody 97A6 is identical to the ectonucleotide pyrophosphatase/phosphodiesterase 3 HJ Bühring, M Seiffert, C Giesert, A Marxer, L Kanz, P Valent, K Sano Blood, The Journal of the American Society of Hematology 97 (10), 3303-3305, 2001 | 177 | 2001 |
Depletion of CLL-associated patrolling monocytes and macrophages controls disease development and repairs immune dysfunction in vivo BS Hanna, F McClanahan, H Yazdanparast, N Zaborsky, V Kalter, ... Leukemia 30 (3), 570-579, 2016 | 151 | 2016 |
Dissecting intratumour heterogeneity of nodal B-cell lymphomas at the transcriptional, genetic and drug-response levels T Roider, J Seufert, A Uvarovskii, F Frauhammer, M Bordas, N Abedpour, ... Nature cell biology 22 (7), 896-906, 2020 | 139 | 2020 |
BRAF inhibition in hairy cell leukemia with low-dose vemurafenib S Dietrich, A Pircher, V Endris, F Peyrade, CM Wendtner, GA Follows, ... Blood, The Journal of the American Society of Hematology 127 (23), 2847-2855, 2016 | 135 | 2016 |
Characterization and functional analysis of laminin isoforms in human bone marrow U Siler, M Seiffert, S Puch, A Richards, B Torok-Storb, CA Müller, ... Blood, The Journal of the American Society of Hematology 96 (13), 4194-4203, 2000 | 131 | 2000 |
Inflammatory cytokines and signaling pathways are associated with survival of primary chronic lymphocytic leukemia cells in vitro: a dominant role of CCL2 A Schulz, G Toedt, T Zenz, S Stilgenbauer, P Lichter, M Seiffert Haematologica 96 (3), 408, 2010 | 111 | 2010 |
T-cells in chronic lymphocytic leukemia: guardians or drivers of disease? PM Roessner, M Seiffert Leukemia 34 (8), 2012-2024, 2020 | 109 | 2020 |
Gab3, a new DOS/Gab family member, facilitates macrophage differentiation I Wolf, BJ Jenkins, Y Liu, M Seiffert, JM Custodio, P Young, ... Molecular and Cellular Biology 22 (1), 231-244, 2002 | 108 | 2002 |
Expression of Novel Surface Antigens on Early Hematopoietic Cellsa HJ BÜHRING, M Seiffert, TA Bock, S Scheding, A Thiel, A Scheffold, ... Annals of the New York Academy of Sciences 872 (1), 25-39, 1999 | 96 | 1999 |
Branched‐chain ketoacids secreted by glioblastoma cells via MCT 1 modulate macrophage phenotype LS Silva, G Poschet, Y Nonnenmacher, HM Becker, S Sapcariu, ... EMBO reports 18 (12), 2172-2185, 2017 | 94 | 2017 |
Soluble CD14 is a novel monocyte-derived survival factor for chronic lymphocytic leukemia cells, which is induced by CLL cells in vitro and present at abnormally high levels in … M Seiffert, A Schulz, S Ohl, H Döhner, S Stilgenbauer, P Lichter Blood, The Journal of the American Society of Hematology 116 (20), 4223-4230, 2010 | 92 | 2010 |
Efficient nucleofection of primary human B cells and B-CLL cells induces apoptosis, which depends on the microenvironment and on the structure of transfected nucleic acids M Seiffert, S Stilgenbauer, H Döhner, P Lichter Leukemia 21 (9), 1977-1983, 2007 | 88 | 2007 |