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Jessica Okosun
Jessica Okosun
Professor of Translational Cancer Research, Barts Cancer Institute, Queen Mary University of London
E-mail confirmado em qmul.ac.uk
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Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma
J Okosun, C Bödör, J Wang, S Araf, CY Yang, C Pan, S Boller, D Cittaro, ...
Nature genetics 46 (2), 176-181, 2014
7892014
EZH2 mutations are frequent and represent an early event in follicular lymphoma
C Bödör, V Grossmann, N Popov, J Okosun, C O’Riain, K Tan, J Marzec, ...
Blood, The Journal of the American Society of Hematology 122 (18), 3165-3168, 2013
3732013
Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma
J Okosun, RL Wolfson, J Wang, S Araf, L Wilkins, BM Castellano, ...
Nature genetics 48 (2), 183-188, 2016
2502016
Disease evolution and outcomes in familial AML with germline CEBPA mutations
K Tawana, J Wang, A Renneville, C Bödör, R Hills, C Loveday, A Savic, ...
Blood, The Journal of the American Society of Hematology 126 (10), 1214-1223, 2015
2212015
HIV status does not influence outcome in patients with classical Hodgkin lymphoma treated with chemotherapy using doxorubicin, bleomycin, vinblastine, and dacarbazine in the …
S Montoto, K Shaw, J Okosun, S Gandhi, P Fields, A Wilson, M Shanyinde, ...
Journal of clinical oncology 30 (33), 4111-4116, 2012
1772012
Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma
S Araf, J Wang, K Korfi, C Pangault, E Kotsiou, A Rio-Machin, T Rahim, ...
Leukemia 32 (5), 1261-1265, 2018
1262018
Clinical outcome of coronavirus disease 2019 in haemato‐oncology patients
JA Aries, JK Davies, RL Auer, SL Hallam, S Montoto, M Smith, B Sevillano, ...
British journal of haematology 190 (2), e64, 2020
1042020
Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma
L Mansouri, D Noerenberg, E Young, E Mylonas, M Abdulla, M Frick, ...
Blood, The Journal of the American Society of Hematology 128 (23), 2666-2670, 2016
1022016
Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors
SJ Horton, G Giotopoulos, H Yun, S Vohra, O Sheppard, ...
Nature cell biology 19 (9), 1093-1104, 2017
712017
Follicular lymphoma: recent and emerging therapies, treatment strategies, and remaining unmet needs
MJ Matasar, S Luminari, PM Barr, SK Barta, AV Danilov, BT Hill, ...
The oncologist 24 (11), e1236-e1250, 2019
582019
Oncogenic Rag GTPase signalling enhances B cell activation and drives follicular lymphoma sensitive to pharmacological inhibition of mTOR
A Ortega-Molina, N Deleyto-Seldas, J Carreras, A Sanz, ...
Nature metabolism 1 (8), 775-789, 2019
562019
Pathogenesis of follicular lymphoma: genetics to the microenvironment to clinical translation
E Kumar, L Pickard, J Okosun
British Journal of Haematology 194 (5), 810-821, 2021
432021
KDM5 inhibition offers a novel therapeutic strategy for the treatment of KMT2D mutant lymphomas
J Heward, L Koniali, A D’Avola, K Close, A Yeomans, M Philpott, ...
Blood, The Journal of the American Society of Hematology 138 (5), 370-381, 2021
422021
TNFRSF14 aberrations in follicular lymphoma increase clinically significant allogeneic T-cell responses
E Kotsiou, J Okosun, C Besley, S Iqbal, J Matthews, J Fitzgibbon, ...
Blood, The Journal of the American Society of Hematology 128 (1), 72-81, 2016
362016
IGHV sequencing reveals acquired N-glycosylation sites as a clonal and stable event during follicular lymphoma evolution
M Odabashian, E Carlotti, S Araf, J Okosun, F Spada, JG Gribben, ...
Blood, The Journal of the American Society of Hematology 135 (11), 834-844, 2020
302020
Epigenetic dysregulation in follicular lymphoma
S Araf, J Okosun, L Koniali, J Fitzgibbon, J Heward
Epigenomics 8 (1), 77-84, 2016
282016
Interim fluoro-2-deoxy-D-glucose–PET predicts response and progression-free survival in patients with Hodgkin lymphoma and HIV infection
J Okosun, V Warbey, K Shaw, S Montoto, P Fields, R Marcus, A Virchis, ...
Aids 26 (7), 861-865, 2012
252012
The routes for transformation of follicular lymphoma
J Okosun, S Montoto, J Fitzgibbon
Current opinion in hematology 23 (4), 385-391, 2016
232016
Thyroid MALT lymphoma: self-harm to gain potential T-cell help
F Wu, N Watanabe, MM Tzioni, A Akarca, C Zhang, Y Li, Z Chen, F Cucco, ...
Leukemia 35 (12), 3497-3508, 2021
222021
Revising the treatment pathways in lymphoma: new standards of care-how do we choose?
H Ngu, R Takiar, T Phillips, J Okosun, LH Sehn
American Society of Clinical Oncology educational book. American Society of …, 2022
172022
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