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carmine settembre
carmine settembre
Assistant Investigator, TIGEM institute
E-mail confirmado em tigem.it
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13861*2021
TFEB links autophagy to lysosomal biogenesis
C Settembre, C Di Malta, VA Polito, MG Arencibia, F Vetrini, S Erdin, ...
science 332 (6036), 1429-1433, 2011
31842011
A lysosome‐to‐nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
C Settembre, R Zoncu, DL Medina, F Vetrini, S Erdin, SU Erdin, T Huynh, ...
The EMBO journal 31 (5), 1095-1108, 2012
19922012
Signals from the lysosome: a control centre for cellular clearance and energy metabolism
C Settembre, A Fraldi, DL Medina, A Ballabio
Nature reviews Molecular cell biology 14 (5), 283-296, 2013
17832013
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB
DL Medina, S Di Paola, I Peluso, A Armani, D De Stefani, R Venditti, ...
Nature cell biology 17 (3), 288-299, 2015
13162015
TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop
C Settembre, R De Cegli, G Mansueto, PK Saha, F Vetrini, O Visvikis, ...
Nature cell biology 15 (6), 647-658, 2013
10042013
Genetic control of bone formation
G Karsenty, HM Kronenberg, C Settembre
Annual Review of Cell and Developmental 25 (1), 629-648, 2009
8032009
A block of autophagy in lysosomal storage disorders
C Settembre, A Fraldi, L Jahreiss, C Spampanato, C Venturi, D Medina, ...
Human molecular genetics 17 (1), 119-129, 2008
6062008
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition
A Luciani, VR Villella, S Esposito, N Brunetti-Pierri, D Medina, ...
Nature cell biology 12 (9), 863-875, 2010
5392010
TFEB regulates autophagy: an integrated coordination of cellular degradation and recycling processes
C Settembre, A Ballabio
Autophagy 7 (11), 1379-1381, 2011
2862011
Wilson disease protein ATP7B utilizes lysosomal exocytosis to maintain copper homeostasis
EV Polishchuk, M Concilli, S Iacobacci, G Chesi, N Pastore, P Piccolo, ...
Developmental cell 29 (6), 686-700, 2014
2772014
Transcriptional regulation of autophagy: mechanisms and diseases
C Di Malta, L Cinque, C Settembre
Frontiers in cell and developmental biology 7, 114, 2019
2552019
Direct conversion of fibroblasts into functional astrocytes by defined transcription factors
M Caiazzo, S Giannelli, P Valente, G Lignani, A Carissimo, A Sessa, ...
Stem cell reports 4 (1), 25-36, 2015
2552015
Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelae
R Emanuel, I Sergin, S Bhattacharya, JN Turner, S Epelman, C Settembre, ...
Arteriosclerosis, thrombosis, and vascular biology 34 (9), 1942-1952, 2014
2352014
A selective ER‐phagy exerts procollagen quality control via a Calnexin‐FAM 134B complex
A Forrester, C De Leonibus, P Grumati, E Fasana, M Piemontese, ...
The EMBO journal 38 (2), e99847, 2019
2272019
Lysosome: regulator of lipid degradation pathways
C Settembre, A Ballabio
Trends in cell biology 24 (12), 743-750, 2014
2212014
Autophagy is required for memory formation and reverses age-related memory decline
M Glatigny, S Moriceau, M Rivagorda, M Ramos-Brossier, AC Nascimbeni, ...
Current Biology 29 (3), 435-448. e8, 2019
2152019
STUB 1 regulates TFEB‐induced autophagy–lysosome pathway
Y Sha, L Rao, C Settembre, A Ballabio, NT Eissa
The EMBO journal 36 (17), 2544-2552, 2017
2152017
Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth
C Di Malta, D Siciliano, A Calcagni, J Monfregola, S Punzi, N Pastore, ...
Science 356 (6343), 1188-1192, 2017
2072017
A RANKL–PKCβ–TFEB signaling cascade is necessary for lysosomal biogenesis in osteoclasts
M Ferron, C Settembre, J Shimazu, J Lacombe, S Kato, DJ Rawlings, ...
Genes & development 27 (8), 955-969, 2013
2052013
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