| Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs LP Lim, NC Lau, P Garrett-Engele, A Grimson, JM Schelter, J Castle, ... Nature 433 (7027), 769-773, 2005 | 6054 | 2005 |
| Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays JM Johnson, J Castle, P Garrett-Engele, Z Kan, PM Loerch, CD Armour, ... Science 302 (5653), 2141-2144, 2003 | 1847 | 2003 |
| AACR Project GENIE: powering precision medicine through an international consortium AACR Project Genie Consortium, AACR Project GENIE Consortium, ... Cancer discovery 7 (8), 818-831, 2017 | 1420 | 2017 |
| Mapping the genetic architecture of gene expression in human liver EE Schadt, C Molony, E Chudin, K Hao, X Yang, PY Lum, A Kasarskis, ... PLoS biology 6 (5), e107, 2008 | 1204 | 2008 |
| Position-specific chemical modification of siRNAs reduces “off-target” transcript silencing AL Jackson, J Burchard, D Leake, A Reynolds, J Schelter, J Guo, ... Rna 12 (7), 1197-1205, 2006 | 1079 | 2006 |
| Plasma MicroRNAs as sensitive and specific biomarkers of tissue injury OF Laterza, L Lim, PW Garrett-Engele, K Vlasakova, N Muniappa, ... Clinical chemistry 55 (11), 1977-1983, 2009 | 772 | 2009 |
| A quantitative atlas of polyadenylation in five mammals A Derti, P Garrett-Engele, KD MacIsaac, RC Stevens, S Sriram, R Chen, ... Genome research 22 (6), 1173-1183, 2012 | 735 | 2012 |
| Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression PS Linsley, J Schelter, J Burchard, M Kibukawa, MM Martin, SR Bartz, ... Molecular and cellular biology 27 (6), 2240-2252, 2007 | 684 | 2007 |
| A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart A Kalsotra, X Xiao, AJ Ward, JC Castle, JM Johnson, CB Burge, ... Proceedings of the National Academy of Sciences 105 (51), 20333-20338, 2008 | 576 | 2008 |
| Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2 JI Young, EP Hong, JC Castle, J Crespo-Barreto, AB Bowman, MF Rose, ... Proceedings of the National Academy of Sciences 102 (49), 17551-17558, 2005 | 570 | 2005 |
| Simple, quantitative primer-extension PCR assay for direct monitoring of microRNAs and short-interfering RNAs CK Raymond, BS Roberts, P Garrett-Engele, LP Lim, JM Johnson Rna 11 (11), 1737-1744, 2005 | 544 | 2005 |
| Dark matter in the genome: evidence of widespread transcription detected by microarray tiling experiments JM Johnson, S Edwards, D Shoemaker, EE Schadt TRENDS in Genetics 21 (2), 93-102, 2005 | 456 | 2005 |
| Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines JC Castle, C Zhang, JK Shah, AV Kulkarni, A Kalsotra, TA Cooper, ... Nature genetics 40 (12), 1416-1425, 2008 | 376 | 2008 |
| Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2 C Zhang, Z Zhang, J Castle, S Sun, J Johnson, AR Krainer, MQ Zhang Genes & development 22 (18), 2550-2563, 2008 | 351 | 2008 |
| Expression profiles of 50 xenobiotic transporter genes in humans and pre-clinical species: a resource for investigations into drug disposition K Bleasby, JC Castle, CJ Roberts, C Cheng, WJ Bailey, JF Sina, ... Xenobiotica 36 (10-11), 963-988, 2006 | 323 | 2006 |
| Digital transcriptome profiling using selective hexamer priming for cDNA synthesis CD Armour, JC Castle, R Chen, T Babak, P Loerch, S Jackson, JK Shah, ... Nature methods 6 (9), 647-649, 2009 | 245 | 2009 |
| Alignment and structure prediction of divergent protein families: periplasmic and outer membrane proteins of bacterial efflux pumps JM Johnson, GM Church Journal of molecular biology 287 (3), 695-715, 1999 | 233 | 1999 |
| Analysis and visualization of longitudinal genomic and clinical data from the AACR project GENIE biopharma collaborative in cBioPortal I de Bruijn, R Kundra, B Mastrogiacomo, TN Tran, L Sikina, T Mazor, X Li, ... Cancer research 83 (23), 3861-3867, 2023 | 224 | 2023 |
| Global survey of genomic imprinting by transcriptome sequencing T Babak, B DeVeale, C Armour, C Raymond, MA Cleary, D van der Kooy, ... Current biology 18 (22), 1735-1741, 2008 | 204 | 2008 |
| Definition, conservation and epigenetics of housekeeping and tissue-enriched genes X She, CA Rohl, JC Castle, AV Kulkarni, JM Johnson, R Chen BMC genomics 10, 1-12, 2009 | 194 | 2009 |
John C. CastleChief Data Scientist, Monte Rosa TherapeuticsE-mail confirmado em monterosatx.com
