Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13817* | 2021 |
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ... Cell Death & Differentiation 25 (3), 486-541, 2018 | 6053 | 2018 |
Molecular characterization of mitochondrial apoptosis-inducing factor SA Susin, HK Lorenzo, N Zamzami, I Marzo, BE Snow, GM Brothers, ... Nature 397 (6718), 441-446, 1999 | 5469 | 1999 |
Cerebral organoids model human brain development and microcephaly MA Lancaster, M Renner, CA Martin, D Wenzel, LS Bicknell, ME Hurles, ... Nature 501 (7467), 373-379, 2013 | 5119 | 2013 |
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis YY Kong, H Yoshida, I Sarosi, HL Tan, E Timms, C Capparelli, S Morony, ... Nature 397 (6717), 315-323, 1999 | 4291 | 1999 |
A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury K Kuba, Y Imai, S Rao, H Gao, F Guo, B Guan, Y Huan, P Yang, Y Zhang, ... Nature medicine 11 (8), 875-879, 2005 | 4194 | 2005 |
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4 P Waterhouse, JM Penninger, E Timms, A Wakeham, A Shahinian, ... Science 270 (5238), 985-988, 1995 | 3670 | 1995 |
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN V Stambolic, A Suzuki, JL De La Pompa, GM Brothers, C Mirtsos, T Sasaki, ... Cell 95 (1), 29-39, 1998 | 3318 | 1998 |
Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target H Zhang, JM Penninger, Y Li, N Zhong, AS Slutsky Intensive care medicine 46, 586-590, 2020 | 3312 | 2020 |
Angiotensin-converting enzyme 2 protects from severe acute lung failure Y Imai, K Kuba, S Rao, Y Huan, F Guo, B Guan, P Yang, R Sarao, T Wada, ... Nature 436 (7047), 112-116, 2005 | 3021 | 2005 |
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand YY Kong, U Feige, I Sarosi, B Bolon, A Tafuri, S Morony, C Capparelli, J Li, ... Nature 402 (6759), 304-309, 1999 | 2385 | 1999 |
Angiotensin-converting enzyme 2 is an essential regulator of heart function MA Crackower, R Sarao, GY Oudit, C Yagil, I Kozieradzki, SE Scanga, ... Nature 417 (6891), 822-828, 2002 | 2334 | 2002 |
Inhibition of SARS-CoV-2 infections in engineered human tissues using clinical-grade soluble human ACE2 V Monteil, H Kwon, P Prado, A Hagelkrüys, RA Wimmer, M Stahl, ... Cell 181 (4), 905-913. e7, 2020 | 2333 | 2020 |
Evidence for osteocyte regulation of bone homeostasis through RANKL expression T Nakashima, M Hayashi, T Fukunaga, K Kurata, M Oh-Hora, JQ Feng, ... Nature medicine 17 (10), 1231-1234, 2011 | 2010 | 2011 |
Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death N Joza, SA Susin, E Daugas, WL Stanford, SK Cho, CYJ Li, T Sasaki, ... Nature 410 (6828), 549-554, 2001 | 1984 | 2001 |
Mitogen-activated protein kinases in apoptosis regulation T Wada, JM Penninger Oncogene 23 (16), 2838-2849, 2004 | 1850 | 2004 |
Differential requirement for caspase 9 in apoptotic pathways in vivo R Hakem, A Hakem, GS Duncan, JT Henderson, M Woo, MS Soengas, ... Cell 94 (3), 339-352, 1998 | 1668 | 1998 |
Molecular definitions of autophagy and related processes L Galluzzi, EH Baehrecke, A Ballabio, P Boya, JM Bravo‐San Pedro, ... The EMBO journal 36 (13), 1811-1836, 2017 | 1653 | 2017 |
Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury Y Imai, K Kuba, GG Neely, R Yaghubian-Malhami, T Perkmann, ... Cell 133 (2), 235-249, 2008 | 1593 | 2008 |
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling MA Lomaga, WC Yeh, I Sarosi, GS Duncan, C Furlonger, A Ho, S Morony, ... Genes & development 13 (8), 1015-1024, 1999 | 1593 | 1999 |