| PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum MF Offield, TL Jetton, PA Labosky, M Ray, RW Stein, MA Magnuson, ... Development 122 (3), 983-995, 1996 | 1868 | 1996 |
| Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction MD Michael, RN Kulkarni, C Postic, SF Previs, GI Shulman, ... Molecular cell 6 (1), 87-97, 2000 | 1643 | 2000 |
| Tissue-specific knockout of the insulin receptor in pancreatic β cells creates an insulin secretory defect similar to that in type 2 diabetes RN Kulkarni, JC Brüning, JN Winnay, C Postic, MA Magnuson, CR Kahn Cell 96 (3), 329-339, 1999 | 1518 | 1999 |
| Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic β cell-specific gene knock-outs using Cre recombinase C Postic, M Shiota, KD Niswender, TL Jetton, Y Chen, JM Moates, ... Journal of Biological Chemistry 274 (1), 305-315, 1999 | 1506 | 1999 |
| Thiazolidinediones expand body fluid volume through PPARγ stimulation of ENaC-mediated renal salt absorption YF Guan, C Hao, DR Cha, R Rao, W Lu, DE Kohan, MA Magnuson, ... Nature medicine 11 (8), 861-866, 2005 | 731 | 2005 |
| Identification of Protor as a novel Rictor-binding component of mTOR complex-2 LR Pearce, X Huang, J Boudeau, R Pawłowski, S Wullschleger, M Deak, ... Biochemical Journal 405 (3), 513-522, 2007 | 649 | 2007 |
| Allosteric activators of glucokinase: potential role in diabetes therapy J Grimsby, R Sarabu, WL Corbett, NE Haynes, FT Bizzarro, JW Coffey, ... Science 301 (5631), 370-373, 2003 | 642 | 2003 |
| Deletion of PPARγ in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance JR Jones, C Barrick, KA Kim, J Lindner, B Blondeau, Y Fujimoto, M Shiota, ... Proceedings of the National Academy of Sciences 102 (17), 6207-6212, 2005 | 639 | 2005 |
| Neonatal diabetes mellitus due to complete glucokinase deficiency PR Njølstad, O Søvik, A Cuesta-Muñoz, L Bjørkhaug, O Massa, F Barbetti, ... New England Journal of Medicine 344 (21), 1588-1592, 2001 | 579 | 2001 |
| Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression R Dentin, JP Pégorier, F Benhamed, F Foufelle, P Ferré, V Fauveau, ... Journal of Biological Chemistry 279 (19), 20314-20326, 2004 | 540 | 2004 |
| Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways K Lee, P Gudapati, S Dragovic, C Spencer, S Joyce, N Killeen, ... Immunity 32 (6), 743-753, 2010 | 528 | 2010 |
| Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity B Stiles, Y Wang, A Stahl, S Bassilian, WP Lee, YJ Kim, R Sherwin, ... Proceedings of the National Academy of Sciences 101 (7), 2082-2087, 2004 | 518 | 2004 |
| Impaired insulin secretion and β-cell loss in tissue-specific knockout mice with mitochondrial diabetes JP Silva, M Köhler, C Graff, A Oldfors, MA Magnuson, PO Berggren, ... Nature genetics 26 (3), 336-340, 2000 | 511 | 2000 |
| mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice DA Guertin, DM Stevens, M Saitoh, S Kinkel, K Crosby, JH Sheen, ... Cancer cell 15 (2), 148-159, 2009 | 499 | 2009 |
| Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability C Shiota, JT Woo, J Lindner, KD Shelton, MA Magnuson Developmental cell 11 (4), 583-589, 2006 | 498 | 2006 |
| Salt–sensitive hypertension and reduced fertility in mice lacking the prostaglandin EP2 receptor CRJ Kennedy, Y Zhang, S Brandon, Y Guan, K Coffee, CD Funk, ... Nature medicine 5 (2), 217-220, 1999 | 491 | 1999 |
| β-cell–specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter β-cell mass RN Kulkarni, M Holzenberger, DQ Shih, U Ozcan, M Stoffel, ... Nature genetics 31 (1), 111-115, 2002 | 451 | 2002 |
| Pancreatic beta-cell glucokinase: closing the gap between theoretical concepts and experimental realities. FM Matschinsky, B Glaser, MA Magnuson Diabetes 47 (3), 307-315, 1998 | 448 | 1998 |
| DNA excision in liver by an albumin‐Cre transgene occurs progressively with age C Postic, MA Magnuson genesis 26 (2), 149-150, 2000 | 431 | 2000 |
| Identification of a sequence in the PEPCK gene that mediates a negative effect of insulin on transcription RM O'Brien, PC Lucas, CD Forest, MA Magnuson, DK Granner Science 249 (4968), 533-537, 1990 | 420 | 1990 |
Catherine PosticInstitut CochinE-mail confirmado em inserm.fr