| How mitochondria produce reactive oxygen species MP Murphy Biochemical journal 417 (1), 1-13, 2009 | 9312 | 2009 |
| Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS ET Chouchani, VR Pell, E Gaude, D Aksentijević, SY Sundier, EL Robb, ... Nature 515 (7527), 431-435, 2014 | 2642 | 2014 |
| Succinate dehydrogenase supports metabolic repurposing of mitochondria to drive inflammatory macrophages EL Mills, B Kelly, A Logan, ASH Costa, M Varma, CE Bryant, ... Cell 167 (2), 457-470. e13, 2016 | 1873 | 2016 |
| Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 EL Mills, DG Ryan, HA Prag, D Dikovskaya, D Menon, Z Zaslona, ... Nature 556 (7699), 113-117, 2018 | 1473 | 2018 |
| Targeting antioxidants to mitochondria by conjugation to lipophilic cations MP Murphy, RAJ Smith Annu. Rev. Pharmacol. Toxicol. 47 (1), 629-656, 2007 | 1326 | 2007 |
| Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties GF Kelso, CM Porteous, CV Coulter, G Hughes, WK Porteous, ... Journal of Biological Chemistry 276 (7), 4588-4596, 2001 | 1320 | 2001 |
| Unraveling the biological roles of reactive oxygen species MP Murphy, A Holmgren, NG Larsson, B Halliwell, CJ Chang, ... Cell metabolism 13 (4), 361-366, 2011 | 917 | 2011 |
| Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology H Sies, VV Belousov, NS Chandel, MJ Davies, DP Jones, GE Mann, ... Nature reviews Molecular cell biology 23 (7), 499-515, 2022 | 911 | 2022 |
| Selective fluorescent imaging of superoxide in vivo using ethidium-based probes KM Robinson, MS Janes, M Pehar, JS Monette, MF Ross, TM Hagen, ... Proceedings of the National Academy of Sciences 103 (41), 15038-15043, 2006 | 900 | 2006 |
| Delivery of bioactive molecules to mitochondria in vivo RAJ Smith, CM Porteous, AM Gane, MP Murphy Proceedings of the National Academy of Sciences 100 (9), 5407-5412, 2003 | 847 | 2003 |
| Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes K Green, MD Brand, MP Murphy Diabetes 53 (suppl_1), S110-S118, 2004 | 754 | 2004 |
| Redox homeostasis and mitochondrial dynamics PHGM Willems, R Rossignol, CEJ Dieteren, MP Murphy, WJH Koopman Cell metabolism 22 (2), 207-218, 2015 | 727 | 2015 |
| Targeting an antioxidant to mitochondria decreases cardiac ischemia‐reperfusion injury VJ Adlam, JC Harrison, CM Porteous, AM James, RAJ Smith, MP Murphy, ... The FASEB Journal 19 (9), 1088-1095, 2005 | 723 | 2005 |
| A unifying mechanism for mitochondrial superoxide production during ischemia-reperfusion injury ET Chouchani, VR Pell, AM James, LM Work, K Saeb-Parsy, C Frezza, ... Cell metabolism 23 (2), 254-263, 2016 | 722 | 2016 |
| Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo MP Murphy, H Bayir, V Belousov, CJ Chang, KJA Davies, MJ Davies, ... Nature metabolism 4 (6), 651-662, 2022 | 698 | 2022 |
| Complex I is the major site of mitochondrial superoxide production by paraquat HM Cochemé, MP Murphy Journal of biological chemistry 283 (4), 1786-1798, 2008 | 688 | 2008 |
| The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production EL Bell, TA Klimova, J Eisenbart, CT Moraes, MP Murphy, GRS Budinger, ... The Journal of cell biology 177 (6), 1029-1036, 2007 | 677 | 2007 |
| DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88 V Tarallo, Y Hirano, BD Gelfand, S Dridi, N Kerur, Y Kim, WG Cho, ... Cell 149 (4), 847-859, 2012 | 673 | 2012 |
| Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I ET Chouchani, C Methner, SM Nadtochiy, A Logan, VR Pell, S Ding, ... Nature medicine 19 (6), 753-759, 2013 | 665 | 2013 |
| Mitochondria as a therapeutic target for common pathologies MP Murphy, RC Hartley Nature Reviews Drug Discovery 17 (12), 865-886, 2018 | 660 | 2018 |
