Molecular properties of WHO essential drugs and provisional biopharmaceutical classification NA Kasim, M Whitehouse, C Ramachandran, M Bermejo, H Lennernäs, ... Molecular pharmaceutics 1 (1), 85-96, 2004 | 1080 | 2004 |
A provisional biopharmaceutical classification of the top 200 oral drug products in the United States, Great Britain, Spain, and Japan T Takagi, C Ramachandran, M Bermejo, S Yamashita, LX Yu, GL Amidon Molecular pharmaceutics 3 (6), 631-643, 2006 | 783 | 2006 |
PAMPA—a drug absorption in vitro model: 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones M Bermejo, A Avdeef, A Ruiz, R Nalda, JA Ruell, O Tsinman, I González, ... European journal of pharmaceutical sciences 21 (4), 429-441, 2004 | 251 | 2004 |
Pharmacokinetics in drug discovery A Ruiz‐Garcia, M Bermejo, A Moss, VG Casabo Journal of pharmaceutical sciences 97 (2), 654-690, 2008 | 248 | 2008 |
Usefulness of Caco-2/HT29-MTX and Caco-2/HT29-MTX/Raji B coculture models to predict intestinal and colonic permeability compared to Caco-2 monoculture I Lozoya-Agullo, F Araujo, I Gonzalez-Alvarez, M Merino-Sanjuan, ... Molecular pharmaceutics 14 (4), 1264-1270, 2017 | 176 | 2017 |
Biowaiver monographs for immediate release solid oral dosage forms: Aciclovir J Arnal, I Gonzalez‐Alvarez, M Bermejo, GL Amidon, HE Junginger, ... Journal of pharmaceutical sciences 97 (12), 5061-5073, 2008 | 130 | 2008 |
Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for in Vivo Dissolution and Absorption of Ionizable Drugs B Hens, Y Tsume, M Bermejo, P Paixao, MJ Koenigsknecht, JR Baker, ... Molecular pharmaceutics 14 (12), 4281-4294, 2017 | 129 | 2017 |
Giardiasis: Characteristics, Pathogenesis and New Insights About Treatment V Vivancos, I González-Alvarez, M Bermejo, M Gonzalez-Alvarez Current topics in medicinal chemistry 18 (15), 1287-1303, 2018 | 110 | 2018 |
Cyclometalated Iminophosphorane Gold (III) and Platinum (II) Complexes. A Highly Permeable Cationic Platinum (II) Compound with Promising Anticancer Properties M Frik, J Fernández-Gallardo, O Gonzalo, V Mangas-Sanjuan, ... Journal of medicinal chemistry 58 (15), 5825-5841, 2015 | 103 | 2015 |
Purely in silico BCS classification: Science based quality standards for the world’s drugs A Dahan, O Wolk, YH Kim, C Ramachandran, GM Crippen, T Takagi, ... Molecular pharmaceutics 10 (11), 4378-4390, 2013 | 86 | 2013 |
In-situ intestinal rat perfusions for human Fabs prediction and BCS permeability class determination: Investigation of the single-pass vs. the Doluisio experimental approaches I Lozoya-Agullo, M Zur, O Wolk, A Beig, I González-Álvarez, ... International journal of pharmaceutics 480 (1-2), 1-7, 2015 | 83 | 2015 |
A topological substructural approach for the prediction of P‐glycoprotein substrates MA Cabrera, I González, C Fernández, C Navarro, M Bermejo Journal of pharmaceutical sciences 95 (3), 589-606, 2006 | 82 | 2006 |
Provisional classification and in silico study of biopharmaceutical system based on caco-2 cell permeability and dose number H Pham-The, T Garrigues, M Bermejo, I González-Álvarez, ... Molecular pharmaceutics 10 (6), 2445-2461, 2013 | 75 | 2013 |
In Situ Perfusion Model in Rat Colon for Drug Absorption Studies: Comparison with Small Intestine and Caco‐2 Cell Model I Lozoya‐Agullo, I González‐Álvarez, M González‐Álvarez, ... Journal of pharmaceutical sciences 104 (9), 3136-3145, 2015 | 73 | 2015 |
In Silico Prediction of Caco‐2 Cell Permeability by a Classification QSAR Approach H Pham The, I González‐Álvarez, M Bermejo, V Mangas Sanjuan, ... Molecular Informatics 30 (4), 376-385, 2011 | 70 | 2011 |
Covalently crosslinked organophosphorous derivatives-chitosan hydrogel as a drug delivery system for oral administration of camptothecin M Martínez-Martínez, G Rodríguez-Berna, M Bermejo, I Gonzalez-Alvarez, ... European Journal of Pharmaceutics and Biopharmaceutics 136, 174-183, 2019 | 64 | 2019 |
Segmental-dependent permeability throughout the small intestine following oral drug administration: Single-pass vs. Doluisio approach to in-situ rat perfusion I Lozoya-Agullo, M Zur, A Beig, N Fine, Y Cohen, M González-Álvarez, ... International journal of pharmaceutics 515 (1-2), 201-208, 2016 | 58 | 2016 |
Evaluation and optimized selection of supersaturating drug delivery systems of posaconazole (BCS class 2b) in the gastrointestinal simulator (GIS): An in vitro-in silico-in … B Hens, M Bermejo, Y Tsume, I Gonzalez-Alvarez, H Ruan, K Matsui, ... European Journal of Pharmaceutical Sciences 115, 258-269, 2018 | 57 | 2018 |
Ionic hydrogel based on chitosan cross-linked with 6-phosphogluconic trisodium salt as a drug delivery system M Martínez-Martínez, G Rodríguez-Berna, I Gonzalez-Alvarez, ... Biomacromolecules 19 (4), 1294-1304, 2018 | 57 | 2018 |
Formulation predictive dissolution (fPD) testing to advance oral drug product development: an introduction to the US FDA funded ‘21st Century BA/BE’project B Hens, PD Sinko, N Job, M Dean, J Al-Gousous, N Salehi, RM Ziff, ... International journal of pharmaceutics 548 (1), 120-127, 2018 | 51 | 2018 |