Expression and regulation of neurotrophins in the nondegenerate and degenerate human intervertebral disc D Purmessur, AJ Freemont, JA Hoyland Arthritis research & therapy 10, 1-9, 2008 | 248 | 2008 |
Complex loading affects intervertebral disc mechanics and biology BA Walter, CL Korecki, D Purmessur, PJ Roughley, AJ Michalek, ... Osteoarthritis and cartilage 19 (8), 1011-1018, 2011 | 245 | 2011 |
A role for TNFα in intervertebral disc degeneration: a non-recoverable catabolic shift D Purmessur, BA Walter, PJ Roughley, DM Laudier, AC Hecht, J Iatridis Biochemical and biophysical research communications 433 (1), 151-156, 2013 | 227 | 2013 |
Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells D Purmessur, RM Schek, RD Abbott, BA Ballif, KE Godburn, JC Iatridis Arthritis research & therapy 13, 1-13, 2011 | 134 | 2011 |
Localized intervertebral disc injury leads to organ level changes in structure, cellularity, and biosynthesis JC Iatridis, AJ Michalek, D Purmessur, CL Korecki Cellular and molecular bioengineering 2, 437-447, 2009 | 108 | 2009 |
Soluble factors from the notochordal-rich intervertebral disc inhibit endothelial cell invasion and vessel formation in the presence and absence of pro-inflammatory cytokines MC Cornejo, SK Cho, C Giannarelli, JC Iatridis, D Purmessur Osteoarthritis and cartilage 23 (3), 487-496, 2015 | 106 | 2015 |
Regenerative potential of TGFβ3+ Dex and notochordal cell conditioned media on degenerated human intervertebral disc cells RD Abbott, D Purmessur, RD Monsey, JC Iatridis Journal of orthopaedic research 30 (3), 482-488, 2012 | 93 | 2012 |
Annular puncture with tumor necrosis factor-alpha injection enhances painful behavior with disc degeneration in vivo A Lai, A Moon, D Purmessur, B Skovrlj, DM Laudier, BA Winkelstein, ... The Spine Journal 16 (3), 420-431, 2016 | 92 | 2016 |
Nonoperative management of discogenic back pain: a systematic review Y Lu, JZ Guzman, D Purmessur, JC Iatridis, AC Hecht, SA Qureshi, ... Spine 39 (16), 1314-1324, 2014 | 82 | 2014 |
Reduced tissue osmolarity increases TRPV4 expression and pro-inflammatory cytokines in intervertebral disc cells BA Walter, D Purmessur, A Moon, J Occhiogrosso, DM Laudier, AC Hecht, ... European cells & materials 32, 123, 2016 | 81 | 2016 |
Degenerate human nucleus pulposus cells promote neurite outgrowth in neural cells SM Richardson, D Purmessur, P Baird, B Probyn, AJ Freemont, ... Public Library of Science 7 (10), e47735, 2012 | 80 | 2012 |
Characterization of mechanics and cytocompatibility of fibrin-genipin annulus fibrosus sealant with the addition of cell adhesion molecules CC Guterl, OM Torre, D Purmessur, K Dave, M Likhitpanichkul, AC Hecht, ... Tissue Engineering Part A 20 (17-18), 2536-2545, 2014 | 71 | 2014 |
Assessment of functional and behavioral changes sensitive to painful disc degeneration A Lai, A Moon, D Purmessur, B Skovrlj, BA Winkelstein, SK Cho, ... Journal of Orthopaedic Research 33 (5), 755-764, 2015 | 70 | 2015 |
Mast cell-intervertebral disc cell interactions regulate inflammation, catabolism and angiogenesis in discogenic back pain MG Wiet, A Piscioneri, SN Khan, MN Ballinger, JA Hoyland, D Purmessur Scientific reports 7 (1), 12492, 2017 | 69 | 2017 |
Inflammatory kinetics and efficacy of anti-inflammatory treatments on human nucleus pulposus cells BA Walter, D Purmessur, M Likhitpanichkul, A Weinberg, SK Cho, ... Spine 40 (13), 955-963, 2015 | 64 | 2015 |
Dynamic pressurization induces transition of notochordal cells to a mature phenotype while retaining production of important patterning ligands from development D Purmessur, CC Guterl, SK Cho, MC Cornejo, YW Lam, BA Ballif, ... Arthritis research & therapy 15, 1-14, 2013 | 59 | 2013 |
Intact glycosaminoglycans from intervertebral disc-derived notochordal cell-conditioned media inhibit neurite growth while maintaining neuronal cell viability D Purmessur, MC Cornejo, SK Cho, PJ Roughley, RJ Linhardt, AC Hecht, ... The spine journal 15 (5), 1060-1069, 2015 | 55 | 2015 |
Notochordal cell–derived therapeutic strategies for discogenic back pain D Purmessur, MC Cornejo, SK Cho, AC Hecht, JC Iatridis Global spine journal 3 (3), 201-217, 2013 | 53 | 2013 |
The chondrodystrophic dog: a clinically relevant intermediate‐sized animal model for the study of intervertebral disc‐associated spinal pain K Thompson, S Moore, S Tang, M Wiet, D Purmessur Jor Spine 1 (1), e1011, 2018 | 49 | 2018 |
Non-viral gene delivery methods for bone and joints B Gantenbein, S Tang, J Guerrero, N Higuita-Castro, AI Salazar-Puerta, ... Frontiers in Bioengineering and Biotechnology 8, 598466, 2020 | 45 | 2020 |