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Devina Purmessur
Devina Purmessur
Associate Professor in Biomedical Engineering, The Ohio State University
E-mail confirmado em osu.edu
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Expression and regulation of neurotrophins in the nondegenerate and degenerate human intervertebral disc
D Purmessur, AJ Freemont, JA Hoyland
Arthritis research & therapy 10, 1-9, 2008
2482008
Complex loading affects intervertebral disc mechanics and biology
BA Walter, CL Korecki, D Purmessur, PJ Roughley, AJ Michalek, ...
Osteoarthritis and cartilage 19 (8), 1011-1018, 2011
2452011
A role for TNFα in intervertebral disc degeneration: a non-recoverable catabolic shift
D Purmessur, BA Walter, PJ Roughley, DM Laudier, AC Hecht, J Iatridis
Biochemical and biophysical research communications 433 (1), 151-156, 2013
2272013
Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells
D Purmessur, RM Schek, RD Abbott, BA Ballif, KE Godburn, JC Iatridis
Arthritis research & therapy 13, 1-13, 2011
1342011
Localized intervertebral disc injury leads to organ level changes in structure, cellularity, and biosynthesis
JC Iatridis, AJ Michalek, D Purmessur, CL Korecki
Cellular and molecular bioengineering 2, 437-447, 2009
1082009
Soluble factors from the notochordal-rich intervertebral disc inhibit endothelial cell invasion and vessel formation in the presence and absence of pro-inflammatory cytokines
MC Cornejo, SK Cho, C Giannarelli, JC Iatridis, D Purmessur
Osteoarthritis and cartilage 23 (3), 487-496, 2015
1062015
Regenerative potential of TGFβ3+ Dex and notochordal cell conditioned media on degenerated human intervertebral disc cells
RD Abbott, D Purmessur, RD Monsey, JC Iatridis
Journal of orthopaedic research 30 (3), 482-488, 2012
932012
Annular puncture with tumor necrosis factor-alpha injection enhances painful behavior with disc degeneration in vivo
A Lai, A Moon, D Purmessur, B Skovrlj, DM Laudier, BA Winkelstein, ...
The Spine Journal 16 (3), 420-431, 2016
922016
Nonoperative management of discogenic back pain: a systematic review
Y Lu, JZ Guzman, D Purmessur, JC Iatridis, AC Hecht, SA Qureshi, ...
Spine 39 (16), 1314-1324, 2014
822014
Reduced tissue osmolarity increases TRPV4 expression and pro-inflammatory cytokines in intervertebral disc cells
BA Walter, D Purmessur, A Moon, J Occhiogrosso, DM Laudier, AC Hecht, ...
European cells & materials 32, 123, 2016
812016
Degenerate human nucleus pulposus cells promote neurite outgrowth in neural cells
SM Richardson, D Purmessur, P Baird, B Probyn, AJ Freemont, ...
Public Library of Science 7 (10), e47735, 2012
802012
Characterization of mechanics and cytocompatibility of fibrin-genipin annulus fibrosus sealant with the addition of cell adhesion molecules
CC Guterl, OM Torre, D Purmessur, K Dave, M Likhitpanichkul, AC Hecht, ...
Tissue Engineering Part A 20 (17-18), 2536-2545, 2014
712014
Assessment of functional and behavioral changes sensitive to painful disc degeneration
A Lai, A Moon, D Purmessur, B Skovrlj, BA Winkelstein, SK Cho, ...
Journal of Orthopaedic Research 33 (5), 755-764, 2015
702015
Mast cell-intervertebral disc cell interactions regulate inflammation, catabolism and angiogenesis in discogenic back pain
MG Wiet, A Piscioneri, SN Khan, MN Ballinger, JA Hoyland, D Purmessur
Scientific reports 7 (1), 12492, 2017
692017
Inflammatory kinetics and efficacy of anti-inflammatory treatments on human nucleus pulposus cells
BA Walter, D Purmessur, M Likhitpanichkul, A Weinberg, SK Cho, ...
Spine 40 (13), 955-963, 2015
642015
Dynamic pressurization induces transition of notochordal cells to a mature phenotype while retaining production of important patterning ligands from development
D Purmessur, CC Guterl, SK Cho, MC Cornejo, YW Lam, BA Ballif, ...
Arthritis research & therapy 15, 1-14, 2013
592013
Intact glycosaminoglycans from intervertebral disc-derived notochordal cell-conditioned media inhibit neurite growth while maintaining neuronal cell viability
D Purmessur, MC Cornejo, SK Cho, PJ Roughley, RJ Linhardt, AC Hecht, ...
The spine journal 15 (5), 1060-1069, 2015
552015
Notochordal cell–derived therapeutic strategies for discogenic back pain
D Purmessur, MC Cornejo, SK Cho, AC Hecht, JC Iatridis
Global spine journal 3 (3), 201-217, 2013
532013
The chondrodystrophic dog: a clinically relevant intermediate‐sized animal model for the study of intervertebral disc‐associated spinal pain
K Thompson, S Moore, S Tang, M Wiet, D Purmessur
Jor Spine 1 (1), e1011, 2018
492018
Non-viral gene delivery methods for bone and joints
B Gantenbein, S Tang, J Guerrero, N Higuita-Castro, AI Salazar-Puerta, ...
Frontiers in Bioengineering and Biotechnology 8, 598466, 2020
452020
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