Conventional DCs sample and present myelin antigens in the healthy CNS and allow parenchymal T cell entry to initiate neuroinflammation S Mundt, D Mrdjen, SG Utz, M Greter, B Schreiner, B Becher Science immunology 4 (31), eaau8380, 2019 | 219 | 2019 |
Inhibition of the immunoproteasome ameliorates experimental autoimmune encephalomyelitis M Basler, S Mundt, T Muchamuel, C Moll, J Jiang, M Groettrup, CJ Kirk EMBO molecular medicine 6 (2), 226-238, 2014 | 187 | 2014 |
The immunoproteasome: a novel drug target for autoimmune diseases M Basler, S Mundt, A Bitzer, C Schmidt, M Groettrup Clin Exp Rheumatol 33 (4 Suppl 92), S74-9, 2015 | 146 | 2015 |
The CNS immune landscape from the viewpoint of a T cell S Mundt, M Greter, A Flügel, B Becher Trends in neurosciences 42 (10), 667-679, 2019 | 81 | 2019 |
ATG-dependent phagocytosis in dendritic cells drives myelin-specific CD4+ T cell pathogenicity during CNS inflammation CW Keller, C Sina, MB Kotur, G Ramelli, S Mundt, I Quast, LA Ligeon, ... Proceedings of the National Academy of Sciences 114 (52), E11228-E11237, 2017 | 76 | 2017 |
Twin study reveals non-heritable immune perturbations in multiple sclerosis F Ingelfinger, LA Gerdes, V Kavaka, S Krishnarajah, E Friebel, E Galli, ... Nature 603 (7899), 152-158, 2022 | 65 | 2022 |
Inhibition and deficiency of the immunoproteasome subunit LMP7 attenuates LCMV‐induced meningitis S Mundt, B Engelhardt, CJ Kirk, M Groettrup, M Basler European journal of immunology 46 (1), 104-113, 2016 | 54 | 2016 |
CYBB/NOX2 in conventional DCs controls T cell encephalitogenicity during neuroinflammation CW Keller, MB Kotur, S Mundt, N Dokalis, LA Ligeon, AM Shah, M Prinz, ... Autophagy 17 (5), 1244-1258, 2021 | 51 | 2021 |
Inhibiting the immunoproteasome exacerbates the pathogenesis of systemic Candida albicans infection in mice S Mundt, M Basler, S Buerger, H Engler, M Groettrup Scientific reports 6 (1), 19434, 2016 | 48 | 2016 |
The CNS mononuclear phagocyte system in health and disease S Mundt, M Greter, B Becher Neuron 110 (21), 3497-3512, 2022 | 40 | 2022 |
Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature F Ingelfinger, S Krishnarajah, M Kramer, SG Utz, E Galli, M Lutz, P Zwicky, ... Acta neuropathologica 141, 901-915, 2021 | 36 | 2021 |
Keratinocytes control skin immune homeostasis through de novo–synthesized glucocorticoids TS Phan, L Schink, J Mann, VM Merk, P Zwicky, S Mundt, D Simon, ... Science advances 7 (5), eabe0337, 2021 | 34 | 2021 |
The ubiquitin-like modifier FAT10 is selectively expressed in medullary thymic epithelial cells and modifies T cell selection S Buerger, VL Herrmann, S Mundt, N Trautwein, M Groettrup, M Basler The Journal of Immunology 195 (9), 4106-4116, 2015 | 34 | 2015 |
The immunoproteasome subunit LMP7 is required in the murine thymus for filling up a hole in the T cell repertoire M Basler, S Mundt, M Groettrup European journal of immunology 48 (3), 419-429, 2018 | 26 | 2018 |
Single-cell profiling of immune system alterations in lymphoid, barrier and solid tissues in aged mice S Krishnarajah, F Ingelfinger, E Friebel, D Cansever, A Amorim, ... Nature Aging 2 (1), 74-89, 2022 | 22 | 2022 |
IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation P Zwicky, F Ingelfinger, BM Silva de Melo, F Ruchti, S Schärli, N Puertas, ... Science immunology 6 (64), eabg9012, 2021 | 19 | 2021 |
IL-12 sensing in neurons induces neuroprotective CNS tissue adaptation and attenuates neuroinflammation in mice M Andreadou, F Ingelfinger, D De Feo, TLM Cramer, S Tuzlak, E Friebel, ... Nature Neuroscience 26 (10), 1701-1712, 2023 | 18 | 2023 |
Analgesia in mice with experimental meningitis reduces pain without altering immune parameters S Mundt, M Groettrup, M Basler ALTEX-Alternatives to animal experimentation 32 (3), 183-189, 2015 | 13 | 2015 |
No prolongation of skin allograft survival by immunoproteasome inhibition in mice S Mundt, M Basler, B Sawitzki, M Groettrup Molecular immunology 88, 32-37, 2017 | 12 | 2017 |
High-dimensional analysis of 16 SARS-CoV-2 vaccine combinations reveals lymphocyte signatures correlating with immunogenicity NG Nuñez, J Schmid, L Power, C Alberti, S Krishnarajah, S Kreutmair, ... Nature Immunology 24 (6), 941-954, 2023 | 9 | 2023 |