Brian M. Baker

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Oleg BorbulevychQuantumBio Inc.E-mail confirmado em quantumbioinc.com
Cory AyresAssistant Research Professor, University of Notre DameE-mail confirmado em nd.edu
Lance HellmanAssociate Professor of Human Health Sciences, Nevada State UniversityE-mail confirmado em nevadastate.edu
Nishant SinghUniversity of Notre Dame, Ragon Institute of MGH, Harvard and MITE-mail confirmado em mit.edu
Kurt PiepenbrinkAssistant Professor, The University of Nebraska LincolnE-mail confirmado em unl.edu
Zhiping WengProf & Chair, Department of Genomics and Computational Biology, UMASS Medical SchoolE-mail confirmado em umassmed.edu
Brian G. PierceAssociate Professor, Department of Cell Biology and Molecular Genetics, IBBR, University of MarylandE-mail confirmado em umd.edu
Pramod K Srivastava PhD MDUniversity of Connecticut School of MedicineE-mail confirmado em uchc.edu
David KranzE-mail confirmado em illinois.edu
Steven A. CorcelliUniversity of Notre Dame, Department of Chemistry and BiochemistryE-mail confirmado em nd.edu
Andrew SewellDistinguished Research ProfessorE-mail confirmado em cardiff.ac.uk
Yuan WangRegeneron PharmaceuticalsE-mail confirmado em regeneron.com
David ColeHonorary Professor, Cardiff UniversityE-mail confirmado em cf.ac.uk
George CoukosUniversity Hospital of Lausanne, Ludwig Institute for Cancer ResearchE-mail confirmado em chuv.ch
K. Christopher GarciaStanford University/HHMIE-mail confirmado em stanford.edu
Nicholas P Restifo, MDCellular Immunotherapy ExplorerE-mail confirmado em marbletx.com
Jiaqi MaUniversity of Notre DameE-mail confirmado em nd.edu
Michal Bassani-SternbergAssistant Professor, Ludwig Institute for Cancer Research, Lausanne & Head of Immunopeptidomics UnitE-mail confirmado em chuv.ch
John J MilesJames Cook UniversityE-mail confirmado em jcu.edu.au
Christopher A. Klebanoff, M.D.Associate Member, Memorial Sloan Kettering Cancer CenterE-mail confirmado em mskcc.org

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Brian M. Baker

Department of Chemistry & Biochemistry, University of Notre Dame

E-mail confirmado em nd.edu - Página inicial

structural biology T cells molecular biophysics immunology signaling


Título Ordenar por citações Ordenar por ano Ordenar por título	Citado por Citado por	Ano
Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical YH Ding, BM Baker, DN Garboczi, WE Biddison, DC Wiley Immunity 11 (1), 45-56, 1999	467	1999
Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity F Duan, J Duitama, S Al Seesi, CM Ayres, SA Corcelli, AP Pawashe, ... Journal of Experimental Medicine 211 (11), 2231-2248, 2014	450	2014
Evaluation of linked protonation effects in protein binding reactions using isothermal titration calorimetry BM Baker, KP Murphy Biophysical journal 71 (4), 2049-2055, 1996	402	1996
T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility OY Borbulevych, KH Piepenbrink, BE Gloor, DR Scott, RF Sommese, ... Immunity 31 (6), 885-896, 2009	234	2009
Dissecting the energetics of a protein-protein interaction: the binding of ovomucoid third domain to elastase BM Baker, KP Murphy Journal of molecular biology 268 (2), 557-569, 1997	211	1997
The structure and stability of an HLA-A* 0201/octameric tax peptide complex with an empty conserved peptide-N-terminal binding site AR Khan, BM Baker, P Ghosh, WE Biddison, DC Wiley The Journal of Immunology 164 (12), 6398, 2000	202	2000
Prediction of binding energetics from structure using empirical parameterization BM Baker, KP Murphy Methods in enzymology 295, 294-315, 1998	182	1998
Conversion of a T cell antagonist into an agonist by repairing a defect in the TCR/peptide/MHC interface: implications for TCR signaling BM Baker, SJ Gagnon, WE Biddison, DC Wiley Immunity 13 (4), 475-484, 2000	179	2000
TCRs used in cancer gene therapy cross-react with MART-1/Melan-A tumor antigens via distinct mechanisms OY Borbulevych, SM Santhanagopolan, M Hossain, BM Baker The Journal of Immunology 187 (5), 2453-2463, 2011	178	2011
Conformational changes and flexibility in T-cell receptor recognition of peptide–MHC complexes KM Armstrong, KH Piepenbrink, BM Baker Biochemical Journal 415 (Pt 2), 183, 2008	175	2008
Poor immunogenicity of a self/tumor antigen derives from peptide-MHC-I instability and is independent of tolerance Z Yu, MR Theoret, CE Touloukian, DR Surman, SC Garman, ... Journal of Clinical Investigation 114, 551-559, 2004	156	2004
Increased immunogenicity of an anchor-modified tumor-associated antigen is due to the enhanced stability of the peptide/MHC complex: implications for vaccine design OY Borbulevych, TK Baxter, Z Yu, NP Restifo, BM Baker The Journal of Immunology 174 (8), 4812, 2005	144	2005
Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity JJ Adams, S Narayanan, ME Birnbaum, SS Sidhu, SJ Blevins, MH Gee, ... Nature immunology, 2015	135	2015
Two different T cell receptors use different thermodynamic strategies to recognize the same peptide/MHC ligand RL Davis-Harrison, KM Armstrong, BM Baker Journal of molecular biology 346 (2), 533-550, 2005	128	2005
Prediction of neo-epitope immunogenicity reveals TCR recognition determinants and provides insight into immunoediting J Schmidt, AR Smith, M Magnin, J Racle, JR Devlin, S Bobisse, J Cesbron, ... Cell Reports Medicine 2 (2), 2021	118	2021
Interactions between CLIP-170, tubulin, and microtubules: implications for the mechanism of Clip-170 plus-end tracking behavior ES Folker, BM Baker, HV Goodson Molecular biology of the cell 16 (11), 5373-5384, 2005	116	2005
Structures of MART-126/27-35 Peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition OY Borbulevych, FK Insaidoo, TK Baxter, DJ Powell Jr, LA Johnson, ... Journal of molecular biology 372 (5), 1123-1136, 2007	113	2007
Emerging Concepts in TCR Specificity: Rationalizing and (Maybe) Predicting Outcomes NK Singh, TP Riley, SCB Baker, T Borrman, Z Weng, BM Baker The Journal of Immunology 199 (7), 2203-2213, 2017	108	2017
Structural and dynamic control of T‐cell receptor specificity, cross‐reactivity, and binding mechanism BM Baker, DR Scott, SJ Blevins, WF Hawse Immunological Reviews 250 (1), 10-31, 2012	100	2012
Identification of a Crucial Energetic Footprint on the α1 Helix of Human Histocompatibility Leukocyte Antigen (Hla)-A2 That Provides Functional Interactions for Recognition by … BM Baker, RV Turner, SJ Gagnon, DC Wiley, WE Biddison The Journal of experimental medicine 193 (5), 551, 2001	100	2001

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