Mechanistic influences for mutation induction curves after exposure to DNA-reactive carcinogens SH Doak, GJS Jenkins, GE Johnson, E Quick, EM Parry, JM Parry Cancer research 67 (8), 3904-3911, 2007 | 215 | 2007 |
Detection and characterization of mechanisms of action of aneugenic chemicals EM Parry, JM Parry, C Corso, A Doherty, F Haddad, TF Hermine, ... Mutagenesis 17 (6), 509-521, 2002 | 191 | 2002 |
Radiation-induced transgenerational alterations in genome stability and DNA damage RC Barber, P Hickenbotham, T Hatch, D Kelly, N Topchiy, GM Almeida, ... Oncogene 25 (56), 7336-7342, 2006 | 169 | 2006 |
Do dose response thresholds exist for genotoxic alkylating agents? GJS Jenkins, SH Doak, GE Johnson, E Quick, EM Waters, JM Parry Mutagenesis 20 (6), 389-398, 2005 | 140 | 2005 |
Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment GE Johnson, LG Soeteman‐Hernández, BB Gollapudi, OG Bodger, ... Environmental and molecular mutagenesis 55 (8), 609-623, 2014 | 138 | 2014 |
Quantitative approaches for assessing dose–response relationships in genetic toxicology studies BB Gollapudi, GE Johnson, LG Hernandez, LH Pottenger, KL Dearfield, ... Environmental and molecular mutagenesis 54 (1), 8-18, 2013 | 136 | 2013 |
A review: the current in vivo models for the discovery and utility of new anti-leishmanial drugs targeting cutaneous leishmaniasis ER Mears, F Modabber, R Don, GE Johnson PLoS neglected tropical diseases 9 (9), e0003889, 2015 | 127 | 2015 |
Mammalian Cell HPRT Gene Mutation Assay: Test Methods GE Johnson Genetic Toxicology: Principles and Methods, 55-67, 2012 | 122 | 2012 |
IWGT report on quantitative approaches to genotoxicity risk assessment I. Methods and metrics for defining exposure–response relationships and points of departure (PoDs) JT MacGregor, R Frötschl, PA White, KS Crump, DA Eastmond, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 783, 55-65, 2015 | 121 | 2015 |
IWGT report on quantitative approaches to genotoxicity risk assessment II. Use of point-of-departure (PoD) metrics in defining acceptable exposure limits and assessing human risk JT MacGregor, R Frötschl, PA White, KS Crump, DA Eastmond, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 783, 66-78, 2015 | 120 | 2015 |
Mechanistic investigations of low dose exposures to the genotoxic compounds bisphenol-A and rotenone GE Johnson, EM Parry Mutation Research/Genetic Toxicology and Environmental Mutagenesis 651 (1-2 …, 2008 | 77 | 2008 |
Next generation testing strategy for assessment of genomic damage: A conceptual framework and considerations KL Dearfield, BB Gollapudi, JC Bemis, RD Benz, GR Douglas, ... Environmental and Molecular Mutagenesis 58 (5), 264-283, 2017 | 76 | 2017 |
Non-linear dose–response of DNA-reactive genotoxins: Recommendations for data analysis GE Johnson, SH Doak, SM Griffiths, EL Quick, DOF Skibinski, ZM Zaïr, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 678 (2 …, 2009 | 72 | 2009 |
The Influence of DNA Repair on Non-Linear Dose Responses for Mutation AD Thomas, GJS Jenkins, B Kaina, OG Bodger, T Karl-Heinz, PD Lewis, ... Toxicological Sciences, 2013 | 68 | 2013 |
Empirical analysis of BMD metrics in genetic toxicology part I: in vitro analyses to provide robust potency rankings and support MOA determinations JW Wills, GE Johnson, SH Doak, LG Soeteman-Hernández, W Slob, ... Mutagenesis 31 (3), 255-263, 2016 | 67 | 2016 |
Estimating the carcinogenic potency of chemicals from the in vivo micronucleus test LG Soeteman-Hernández, GE Johnson, W Slob Mutagenesis 31 (3), 347-358, 2016 | 63 | 2016 |
Quantitative interpretation of genetic toxicity dose‐response data for risk assessment and regulatory decision‐making: current status and emerging priorities PA White, AS Long, GE Johnson Environmental and Molecular Mutagenesis 61 (1), 66-83, 2020 | 59 | 2020 |
Mutation as a toxicological endpoint for regulatory decision‐making RH Heflich, GE Johnson, A Zeller, F Marchetti, GR Douglas, KL Witt, ... Environmental and Molecular Mutagenesis 61 (1), 34-41, 2020 | 54 | 2020 |
A mode-of-action approach for the identification of genotoxic carcinogens LG Hernández, J Van Benthem, GE Johnson PLoS One 8 (5), e64532, 2013 | 54 | 2013 |
Genotoxic thresholds, DNA repair, and susceptibility in human populations GJS Jenkins, Z Zaïr, GE Johnson, SH Doak Toxicology 278 (3), 305-310, 2010 | 52 | 2010 |