John C. Castle

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Jason M. JohnsonDana-Farber Cancer Institute, Stanford, Harvard, Pfizer, Merck, PatientsLikeMeE-mail confirmado em dfci.harvard.edu
Ugur SahinProfessor of ImmunologyE-mail confirmado em uni-mainz.de
Dr. Sebastian BoegelPhysician, Bioinformatician, University Hospital MainzE-mail confirmado em students.uni-mainz.de
Mustafa DikenTRON - Translational Oncology at University Medical Center of Johannes Gutenberg UniversityE-mail confirmado em tron-mainz.de
Sebastian KreiterTRON Translational Oncology MainzE-mail confirmado em tron-mainz.de
Zhengyan 'George' KanDirector of Computational Biology, Pfizer Inc.E-mail confirmado em pfizer.com
Özlem TüreciE-mail confirmado em uni-mainz.de
Patrick LoerchGilead SciencesE-mail confirmado em gilead.com
Eric SchadtProfessor of Genetics and Genomic Sciences, Mount Sinai School of MedicineE-mail confirmado em mssm.edu
Peter LinsleyMember and Center Director | Systems Immunology Benaroya Research Institute at Virginia Mason 1201E-mail confirmado em benaroyaresearch.org
Thomas A CooperBaylor College of MedicineE-mail confirmado em bcm.edu
Mohamed UdumanDirector, Immuno-Oncology Computational Biology, Dana-Farber Cancer InstituteE-mail confirmado em dfci.harvard.edu
NELSON LAUBoston University School of Medicine, Dept Biochemistry,E-mail confirmado em bu.edu
David BartelProfessor of Biology, HHMI, MIT, Whitehead InstituteE-mail confirmado em wi.mit.edu
Andrew GrimsonCornell University, Dept. of Molecular Biology and GeneticsE-mail confirmado em cornell.edu
Stephen EdwardsRTI InternationalE-mail confirmado em rti.org
Bernhard RenardHasso Plattner InstituteE-mail confirmado em hpi.de
Kenneth C CreagerProfessor of Earth and Space Sciences, University of WashingtonE-mail confirmado em uw.edu
Huda ZoghbiProfessor Baylor College of MedicineE-mail confirmado em bcm.edu
Aaron B. BowmanPurdue UniversityE-mail confirmado em purdue.edu

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John C. Castle

Chief Data Scientist, Monte Rosa Therapeutics

E-mail confirmado em monterosatx.com - Página inicial

computational biology NGS genomics degraders


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Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs LP Lim, NC Lau, P Garrett-Engele, A Grimson, JM Schelter, J Castle, ... Nature 433 (7027), 769-773, 2005	6054	2005
Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays JM Johnson, J Castle, P Garrett-Engele, Z Kan, PM Loerch, CD Armour, ... Science 302 (5653), 2141-2144, 2003	1847	2003
Mutant MHC class II epitopes drive therapeutic immune responses to cancer S Kreiter, M Vormehr, N Van de Roemer, M Diken, M Löwer, J Diekmann, ... Nature 520 (7549), 692-696, 2015	1363	2015
An integrative genomics approach to infer causal associations between gene expression and disease EE Schadt, J Lamb, X Yang, J Zhu, S Edwards, D GuhaThakurta, ... Nature genetics 37 (7), 710-717, 2005	1244	2005
Exploiting the mutanome for tumor vaccination JC Castle, S Kreiter, J Diekmann, M Löwer, N Van de Roemer, J de Graaf, ... Cancer research 72 (5), 1081-1091, 2012	969	2012
Genome-scale RNAi screen for host factors required for HIV replication H Zhou, M Xu, Q Huang, AT Gates, XD Zhang, JC Castle, E Stec, M Ferrer, ... Cell host & microbe 4 (5), 495-504, 2008	956	2008
Actively personalized vaccination trial for newly diagnosed glioblastoma N Hilf, S Kuttruff-Coqui, K Frenzel, V Bukur, S Stevanović, ... Nature 565 (7738), 240-245, 2019	821	2019
Experimental annotation of the human genome using microarray technology DD Shoemaker, EE Schadt, CD Armour, YD He, P Garrett-Engele, ... Nature 409 (6822), 922-927, 2001	626	2001
A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart A Kalsotra, X Xiao, AJ Ward, JC Castle, JM Johnson, CB Burge, ... Proceedings of the National Academy of Sciences 105 (51), 20333-20338, 2008	576	2008
Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2 JI Young, EP Hong, JC Castle, J Crespo-Barreto, AB Bowman, MF Rose, ... Proceedings of the national academy of sciences 102 (49), 17551-17558, 2005	576	2005
Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma JC Castle, M Loewer, S Boegel, J de Graaf, C Bender, AD Tadmor, ... BMC genomics 15, 1-12, 2014	405	2014
Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines JC Castle, C Zhang, JK Shah, AV Kulkarni, A Kalsotra, TA Cooper, ... Nature genetics 40 (12), 1416-1425, 2008	376	2008
Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2 C Zhang, Z Zhang, J Castle, S Sun, J Johnson, AR Krainer, MQ Zhang Genes & development 22 (18), 2550-2563, 2008	351	2008
Expression profiles of 50 xenobiotic transporter genes in humans and pre-clinical species: a resource for investigations into drug disposition K Bleasby, JC Castle, CJ Roberts, C Cheng, WJ Bailey, JF Sina, ... Xenobiotica 36 (10-11), 963-988, 2006	323	2006
HLA typing from RNA-Seq sequence reads S Boegel, M Löwer, M Schäfer, T Bukur, J De Graaf, V Boisguérin, ... Genome medicine 4, 1-12, 2013	313	2013
Unique signatures of long noncoding RNA expression in response to virus infection and altered innate immune signaling X Peng, L Gralinski, CD Armour, MT Ferris, MJ Thomas, S Proll, ... MBio 1 (5), 10.1128/mbio. 00206-10, 2010	278	2010
Digital transcriptome profiling using selective hexamer priming for cDNA synthesis CD Armour, JC Castle, R Chen, T Babak, P Loerch, S Jackson, JK Shah, ... Nature methods 6 (9), 647-649, 2009	245	2009
Comparative expression pathway analysis of human and canine mammary tumors P Uva, L Aurisicchio, J Watters, A Loboda, A Kulkarni, J Castle, ... BMC genomics 10, 1-20, 2009	209	2009
Definition, conservation and epigenetics of housekeeping and tissue-enriched genes X She, CA Rohl, JC Castle, AV Kulkarni, JM Johnson, R Chen BMC genomics 10, 1-12, 2009	194	2009
Individualized vaccines for cancer U Sahin, S Kreiter, M Diken, J Diekmann, M Koslowski, C Britten, ... US Patent 10,738,355, 2020	188	2020

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