| Divergent pathways mediate spine alterations and cell death induced by amyloid-β, wild-type tau, and R406W tau C Tackenberg, R Brandt Journal of Neuroscience 29 (46), 14439-14450, 2009 | 172 | 2009 |
| NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss C Tackenberg, S Grinschgl, A Trutzel, AC Santuccione, MC Frey, ... Cell death & disease 4 (4), e608-e608, 2013 | 150 | 2013 |
| Oxidative stress and altered mitochondrial protein expression in the absence of amyloid-β and tau pathology in iPSC-derived neurons from sporadic Alzheimer's disease patients JH Birnbaum, D Wanner, AF Gietl, A Saake, TM Kündig, C Hock, ... Stem cell research 27, 121-130, 2018 | 149 | 2018 |
| Thin, stubby or mushroom: spine pathology in Alzheimer's disease C Tackenberg, A Ghori, R Brandt Current Alzheimer Research 6 (3), 261-268, 2009 | 124 | 2009 |
| Tau aggregation and progressive neuronal degeneration in the absence of changes in spine density and morphology after targeted expression of Alzheimer's disease-relevant tau … N Shahani, S Subramaniam, T Wolf, C Tackenberg, R Brandt Journal of Neuroscience 26 (22), 6103-6114, 2006 | 105 | 2006 |
| Calcium flux-independent NMDA receptor activity is required for Aβ oligomer-induced synaptic loss JH Birnbaum, J Bali, L Rajendran, RM Nitsch, C Tackenberg Cell death & disease 6 (6), e1791-e1791, 2015 | 102 | 2015 |
| APOE2, E3, and E4 differentially modulate cellular homeostasis, cholesterol metabolism, and inflammatory response in isogenic iPSC-derived astrocytes SM de Leeuw, AWT Kirschner, K Lindner, R Rust, V Budny, WE Wolski, ... Stem cell reports, 2022 | 68 | 2022 |
| The secreted APP ectodomain sAPPα, but not sAPPβ, protects neurons against Aβ oligomer-induced dendritic spine loss and increased tau phosphorylation C Tackenberg, RM Nitsch Molecular brain 12, 1-4, 2019 | 57 | 2019 |
| Early accumulation of intracellular fibrillar oligomers and late congophilic amyloid angiopathy in mice expressing the Osaka intra-Aβ APP mutation L Kulic, J McAfoose, T Welt, C Tackenberg, C Späni, F Wirth, V Finder, ... Translational psychiatry 2 (11), e183-e183, 2012 | 54 | 2012 |
| Aβ-mediated spine changes in the hippocampus are microtubule-dependent and can be reversed by a subnanomolar concentration of the microtubule-stabilizing agent epothilone D L Penazzi, C Tackenberg, A Ghori, N Golovyashkina, B Niewidok, K Selle, ... Neuropharmacology, 10.1016/j.neuropharm.2016.01.002, 2016 | 51 | 2016 |
| Isoform-and cell-state-specific lipidation of ApoE in astrocytes K Lindner, K Beckenbauer, LC van Ek, K Titeca, SM de Leeuw, K Awwad, ... Cell reports 38 (9), 2022 | 49 | 2022 |
| Deep learning-based behavioral profiling of rodent stroke recovery RZ Weber, G Mulders, J Kaiser, C Tackenberg, R Rust BMC biology 20 (1), 232, 2022 | 44 | 2022 |
| Alzheimer’s in a dish – induced pluripotent stem cell-based disease modeling SM de Leeuw, C Tackenberg Translational Neurodegeneration, 2019 | 41 | 2019 |
| A practical guide to the automated analysis of vascular growth, maturation and injury in the brain R Rust, T Kirabali, L Grönnert, B Dogancay, YDP Limasale, A Meinhardt, ... Frontiers in neuroscience 14, 244, 2020 | 39 | 2020 |
| Genetic ablation of the p66Shc adaptor protein reverses cognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer’s disease R Derungs, GG Camici, RD Spescha, T Welt, C Tackenberg, C Späni, ... Molecular psychiatry 22 (4), 605-614, 2017 | 36 | 2017 |
| Characterization of the blood brain barrier disruption in the photothrombotic stroke model RZ Weber, L Grönnert, G Mulders, MA Maurer, C Tackenberg, ... Frontiers in physiology 11, 586226, 2020 | 35 | 2020 |
| Active vaccination with ankyrin G reduces β-amyloid pathology in APP transgenic mice AC Santuccione, M Merlini, A Shetty, C Tackenberg, J Bali, MT Ferretti, ... Molecular psychiatry 18 (3), 358-368, 2013 | 34 | 2013 |
| Familial Alzheimer’s disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an … C Tackenberg, L Kulic, RM Nitsch PloS one 15 (9), e0239584, 2020 | 31 | 2020 |
| Increased maturation of iPSC-derived neurons in a hydrogel-based 3D culture SM de Leeuw, S Davaz, D Wanner, V Milleret, M Ehrbar, A Gietl, ... Journal of Neuroscience Methods 360, 109254, 2021 | 23 | 2021 |
| Editing a gateway for cell therapy across the blood–brain barrier B Achón Buil, C Tackenberg, R Rust Brain 146 (3), 823-841, 2023 | 20 | 2023 |
