| Ex vivo–expanded but not in vitro–induced human regulatory T cells are candidates for cell therapy in autoimmune diseases thanks to stable demethylation of the FOXP3 regulatory … M Rossetti, R Spreafico, S Saidin, C Chua, M Moshref, JY Leong, YK Tan, ... The Journal of Immunology 194 (1), 113-124, 2015 | 116 | 2015 |
| Enforced IL-10 expression confers type 1 regulatory T cell (Tr1) phenotype and function to human CD4+ T cells G Andolfi, G Fousteri, M Rossetti, CF Magnani, T Jofra, G Locafaro, ... Molecular Therapy 20 (9), 1778-1790, 2012 | 112 | 2012 |
| Increased autophagy in CD4+ T cells of rheumatoid arthritis patients results in T‐cell hyperactivation and apoptosis resistance J van Loosdregt, M Rossetti, R Spreafico, M Moshref, M Olmer, ... European journal of immunology 46 (12), 2862-2870, 2016 | 102 | 2016 |
| A circulating reservoir of pathogenic-like CD4+ T cells shares a genetic and phenotypic signature with the inflamed synovial micro-environment R Spreafico, M Rossetti, J van Loosdregt, CA Wallace, M Massa, ... Annals of the rheumatic diseases 75 (2), 459-465, 2016 | 97 | 2016 |
| Circulating immune cell phenotype dynamics reflect the strength of tumor–immune cell interactions in patients during immunotherapy JI Griffiths, P Wallet, LT Pflieger, D Stenehjem, X Liu, PA Cosgrove, ... Proceedings of the National Academy of Sciences 117 (27), 16072-16082, 2020 | 92 | 2020 |
| Protective immunity in recurrent Staphylococcus aureus infection reflects localized immune signatures and macrophage-conferred memory LC Chan, M Rossetti, LS Miller, SG Filler, CW Johnson, HK Lee, H Wang, ... Proceedings of the National Academy of Sciences 115 (47), E11111-E11119, 2018 | 87 | 2018 |
| TCR repertoire sequencing identifies synovial Treg cell clonotypes in the bloodstream during active inflammation in human arthritis M Rossetti, R Spreafico, A Consolaro, JY Leong, C Chua, M Massa, ... Annals of the rheumatic diseases 76 (2), 435-441, 2017 | 87 | 2017 |
| A flow cytometry-based cytotoxicity assay for the assessment of human NK cell activity F Kandarian, GM Sunga, D Arango-Saenz, M Rossetti Journal of visualized experiments: JoVE, 56191, 2017 | 79 | 2017 |
| Granulocyte‐colony stimulating factor drives the in vitro differentiation of human dendritic cells that induce anergy in naïve T cells M Rossetti, S Gregori, MG Roncarolo European journal of immunology 40 (11), 3097-3106, 2010 | 78 | 2010 |
| Angiotensin II Type 1 receptor antibodies are associated with inflammatory cytokines and poor clinical outcomes in pediatric kidney transplantation MH Pearl, Q Zhang, MFP Diaz, J Grotts, M Rossetti, D Elashoff, ... Kidney international 93 (1), 260-269, 2018 | 76 | 2018 |
| Early cytokine signatures of ischemia/reperfusion injury in human orthotopic liver transplantation RA Sosa, A Zarrinpar, M Rossetti, CR Lassman, BV Naini, N Datta, P Rao, ... JCI insight 1 (20), e89679, 2016 | 72 | 2016 |
| Profiling immunoglobulin repertoires across multiple human tissues using RNA sequencing I Mandric, J Rotman, HT Yang, N Strauli, DJ Montoya, W Van Der Wey, ... Nature communications 11 (1), 3126, 2020 | 71 | 2020 |
| Early effects of first‐line treatment with anti‐interleukin‐6 receptor antibody tocilizumab for chronic active antibody‐mediated rejection in kidney transplantation A Lavacca, R Presta, C Gai, A Mella, E Gallo, G Camussi, I Abbasciano, ... Clinical Transplantation 34 (8), e13908, 2020 | 68 | 2020 |
| Hydroxychloroquine preferentially induces apoptosis of CD45RO+ effector T cells by inhibiting autophagy: a possible mechanism for therapeutic modulation of T cells J van Loosdregt, R Spreafico, M Rossetti, BJ Prakken, M Lotz, S Albani Journal of Allergy and Clinical Immunology 131 (5), 1443-1446. e1, 2013 | 62 | 2013 |
| Diversity in immunogenomics: the value and the challenge K Peng, Y Safonova, M Shugay, AB Popejoy, OL Rodriguez, F Breden, ... Nature methods 18 (6), 588-591, 2021 | 59 | 2021 |
| A screen of Crohn's disease-associated microbial metabolites identifies ascorbate as a novel metabolic inhibitor of activated human T cells YL Chang, M Rossetti, H Vlamakis, D Casero, G Sunga, N Harre, S Miller, ... Mucosal immunology 12 (2), 457-467, 2019 | 59 | 2019 |
| HIV-1-derived lentiviral vectors directly activate plasmacytoid dendritic cells, which in turn induce the maturation of myeloid dendritic cells M Rossetti, S Gregori, E Hauben, BD Brown, LS Sergi, L Naldini, ... Human gene therapy 22 (2), 177-188, 2011 | 55 | 2011 |
| Disulfide high‐mobility group box 1 drives ischemia‐reperfusion injury in human liver transplantation RA Sosa, AQ Terry, FM Kaldas, YP Jin, M Rossetti, T Ito, F Li, RS Ahn, ... Hepatology 73 (3), 1158-1175, 2021 | 54 | 2021 |
| Increased T cell immunosenescence and accelerated maturation phenotypes in older kidney transplant recipients JM Schaenman, M Rossetti, T Sidwell, V Groysberg, G Sunga, Y Korin, ... Human immunology 79 (9), 659-667, 2018 | 51 | 2018 |
| Endothelin type A receptor antibodies are associated with angiotensin II type 1 receptor antibodies, vascular inflammation, and decline in renal function in pediatric kidney … MH Pearl, L Chen, R ElChaki, D Elashoff, DW Gjertson, M Rossetti, ... Kidney International Reports 5 (11), 1925-1936, 2020 | 40 | 2020 |
Roberto SpreaficoGenmabE-mail confirmado em genmab.com