| The chemical genomic portrait of yeast: uncovering a phenotype for all genes ME Hillenmeyer, E Fung, J Wildenhain, SE Pierce, S Hoon, W Lee, ... Science 320 (5874), 362-365, 2008 | 1166 | 2008 |
| Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase NK Kolas, JR Chapman, S Nakada, J Ylanko, R Chahwan, FD Sweeney, ... Science 318 (5856), 1637-1640, 2007 | 1095 | 2007 |
| The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage GS Stewart, S Panier, K Townsend, AK Al-Hakim, NK Kolas, ES Miller, ... Cell 136 (3), 420-434, 2009 | 890 | 2009 |
| BoxPlotR: a web tool for generation of box plots M Spitzer, J Wildenhain, J Rappsilber, M Tyers Nature methods 11 (2), 121-122, 2014 | 837 | 2014 |
| Effects of air temperature on climate-sensitive mortality and morbidity outcomes in the elderly; a systematic review and meta-analysis of epidemiological evidence A Bunker, J Wildenhain, A Vandenbergh, N Henschke, J Rocklöv, S Hajat, ... EBioMedicine 6, 258-268, 2016 | 595 | 2016 |
| Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy L Ejim, MA Farha, SB Falconer, J Wildenhain, BK Coombes, M Tyers, ... Nature chemical biology 7 (6), 348-350, 2011 | 588 | 2011 |
| A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans AR Burns, IM Wallace, J Wildenhain, M Tyers, G Giaever, GD Bader, ... Nature chemical biology 6 (7), 549-557, 2010 | 215 | 2010 |
| Cross‐species discovery of syncretic drug combinations that potentiate the antifungal fluconazole M Spitzer, E Griffiths, KM Blakely, J Wildenhain, L Ejim, L Rossi, ... Molecular systems biology 7 (1), 499, 2011 | 196 | 2011 |
| Chemical genetics reveals a complex functional ground state of neural stem cells P Diamandis, J Wildenhain, ID Clarke, AG Sacher, J Graham, DS Bellows, ... Nature chemical biology 3 (5), 268-273, 2007 | 180 | 2007 |
| The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination L O'Donnell, S Panier, J Wildenhain, JM Tkach, A Al-Hakim, MC Landry, ... Molecular cell 40 (4), 619-631, 2010 | 152 | 2010 |
| Prediction of synergism from chemical-genetic interactions by machine learning J Wildenhain, M Spitzer, S Dolma, N Jarvik, R White, M Roy, E Griffiths, ... Cell Systems 1 (6), 383-395, 2015 | 134 | 2015 |
| Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast E Ericson, M Gebbia, LE Heisler, J Wildenhain, M Tyers, G Giaever, ... PLoS genetics 4 (8), e1000151, 2008 | 115 | 2008 |
| Combined zebrafish-yeast chemical-genetic screens reveal gene–copper-nutrition interactions that modulate melanocyte pigmentation H Ishizaki, M Spitzer, J Wildenhain, C Anastasaki, Z Zeng, S Dolma, ... Disease models & mechanisms 3 (9-10), 639-651, 2010 | 52 | 2010 |
| A Loss of Function Analysis of Host Factors Influencing Vaccinia virus Replication by RNA Interference PM Beard, SJ Griffiths, O Gonzalez, IR Haga, T Pechenick Jowers, ... PLoS One 9 (6), e98431, 2014 | 42 | 2014 |
| Characterizing the roles of Met31 and Met32 in coordinating Met4-activated transcription in the absence of Met30 E Carrillo, G Ben-Ari, J Wildenhain, M Tyers, D Grammentz, TA Lee Molecular Biology of the Cell 23 (10), 1928-1942, 2012 | 33 | 2012 |
| Reconstructing gene regulatory networks: from random to scale-free connectivity J Wildenhain, EJ Crampin IEE Proceedings-Systems Biology 153 (4), 247-256, 2006 | 33 | 2006 |
| onlineFDR: an R package to control the false discovery rate for growing data repositories DS Robertson, J Wildenhain, A Javanmard, NA Karp Bioinformatics 35 (20), 4196-4199, 2019 | 29 | 2019 |
| BioGRID REST Service, BiogridPlugin2 and BioGRID WebGraph: new tools for access to interaction data at BioGRID AG Winter, J Wildenhain, M Tyers Bioinformatics 27 (7), 1043-1044, 2011 | 29 | 2011 |
| A role for intracellular calcium downstream of G-protein signaling in undifferentiated human embryonic stem cell culture A Ermakov, S Pells, P Freile, VV Ganeva, J Wildenhain, M Bradley, ... Stem cell research 9 (3), 171-184, 2012 | 24 | 2012 |
| Chemical interrogation of nuclear size identifies compounds with cancer cell line-specific effects on migration and invasion S Tollis, A Rizzotto, NT Pham, S Koivukoski, A Sivakumar, S Shave, ... ACS chemical biology 17 (3), 680-700, 2022 | 23 | 2022 |
Mike TyersThe Hospital for Sick ChildrenE-mail confirmado em sickkids.ca