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Kate L Weeks, PhD
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Molecular distinction between physiological and pathological cardiac hypertrophy: experimental findings and therapeutic strategies
BC Bernardo, KL Weeks, L Pretorius, JR McMullen
Pharmacology & therapeutics 128 (1), 191-227, 2010
12002010
Pathophysiology of cardiac hypertrophy and heart failure: signaling pathways and novel therapeutic targets
YK Tham, BC Bernardo, JYY Ooi, KL Weeks, JR McMullen
Archives of toxicology 89, 1401-1438, 2015
8072015
The athlete's heart vs. the failing heart: can signaling explain the two distinct outcomes?
KL Weeks, JR McMullen
Physiology 26 (2), 97-105, 2011
2512011
Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin
CE Winbanks, KL Weeks, RE Thomson, PV Sepulveda, C Beyer, H Qian, ...
Journal of Cell Biology 197 (7), 997-1008, 2012
2502012
PI3K (p110α) protects against myocardial infarction-induced heart failure: identification of PI3K-regulated miRNA and mRNA
RCY Lin, KL Weeks, XM Gao, RBH Williams, BC Bernardo, H Kiriazis, ...
Arteriosclerosis, thrombosis, and vascular biology 30 (4), 724-732, 2010
2022010
Understanding key mechanisms of exercise-induced cardiac protection to mitigate disease: current knowledge and emerging concepts
BC Bernardo, JYY Ooi, KL Weeks, NL Patterson, JR McMullen
Physiological Reviews 98 (1), 419-475, 2018
1472018
Phosphoinositide 3-kinase p110α is a master regulator of exercise-induced cardioprotection and PI3K gene therapy rescues cardiac dysfunction
KL Weeks, X Gao, XJ Du, EJH Boey, A Matsumoto, BC Bernardo, ...
Circulation: Heart Failure 5 (4), 523-534, 2012
1422012
The IGF1-PI3K-Akt signaling pathway in mediating exercise-induced cardiac hypertrophy and protection
KL Weeks, BC Bernardo, JYY Ooi, NL Patterson, JR McMullen
Exercise for cardiovascular disease prevention and treatment: from molecular …, 2017
1042017
Histone deacetylases in cardiovascular and metabolic diseases
RA Bagchi, KL Weeks
Journal of Molecular and Cellular Cardiology 130, 151-159, 2019
982019
Phosphoinositide 3-kinase (p110α) gene delivery limits diabetes-induced cardiac NADPH oxidase and cardiomyopathy in a mouse model with established diastolic dysfunction
D Prakoso, MJ De Blasio, C Qin, S Rosli, H Kiriazis, H Qian, XJ Du, ...
Clinical science 131 (12), 1345-1360, 2017
532017
Adeno-associated virus gene therapy: translational progress and future prospects in the treatment of heart failure
S Bass-Stringer, BC Bernardo, CN May, CJ Thomas, KL Weeks, ...
Heart, Lung and Circulation 27 (11), 1285-1300, 2018
442018
Roles and post‐translational regulation of cardiac class IIa histone deacetylase isoforms
KL Weeks, M Avkiran
The Journal of physiology 593 (8), 1785-1797, 2015
402015
Gene therapy targeting cardiac phosphoinositide 3-kinase (p110α) attenuates cardiac remodeling in type 2 diabetes
D Prakoso, MJ De Blasio, M Tate, H Kiriazis, DG Donner, H Qian, D Nash, ...
American Journal of Physiology-Heart and Circulatory Physiology 318 (4 …, 2020
382020
Glycogen-autophagy: Molecular machinery and cellular mechanisms of glycophagy
P Koutsifeli, U Varma, LJ Daniels, M Annandale, X Li, JPH Neale, ...
Journal of Biological Chemistry 298 (7), 2022
372022
β‐Adrenergic Stimulation Induces Histone Deacetylase 5 (HDAC 5) Nuclear Accumulation in Cardiomyocytes by B55α‐PP 2A‐Mediated Dephosphorylation
KL Weeks, A Ranieri, A Karaś, BC Bernardo, AS Ashcroft, C Molenaar, ...
Journal of the American Heart Association 6 (4), e004861, 2017
372017
HSP70: therapeutic potential in acute and chronic cardiac disease settings
BC Bernardo, KL Weeks, NL Patterson, JR McMullen
Future medicinal chemistry 8 (18), 2177-2183, 2016
282016
Assessing structural and functional responses of murine hearts to acute and sustained β-adrenergic stimulation in vivo
SL Puhl, KL Weeks, A Ranieri, M Avkiran
Journal of pharmacological and toxicological methods 79, 60-71, 2016
252016
FoxO1 is required for physiological cardiac hypertrophy induced by exercise but not by constitutively active PI3K
KL Weeks, YK Tham, SG Yildiz, Y Alexander, DG Donner, H Kiriazis, ...
American Journal of Physiology-Heart and Circulatory Physiology 320 (4 …, 2021
232021
Gene delivery of medium chain acyl-coenzyme A dehydrogenase induces physiological cardiac hypertrophy and protects against pathological remodelling
BC Bernardo, KL Weeks, T Pongsukwechkul, X Gao, H Kiriazis, ...
Clinical Science 132 (3), 381-397, 2018
232018
Cellular mechanisms mediating exercise-induced protection against cardiotoxic anthracycline cancer therapy
S Dozic, EJ Howden, JR Bell, KM Mellor, LMD Delbridge, KL Weeks
Cells 12 (9), 1312, 2023
132023
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