| Glycosyltransferases: structures, functions, and mechanisms LL Lairson, B Henrissat, GJ Davies, SG Withers Annu. Rev. Biochem. 77 (1), 521-555, 2008 | 2324 | 2008 |
| Glycosidase mechanisms: anatomy of a finely tuned catalyst DL Zechel, SG Withers Accounts of chemical research 33 (1), 11-18, 2000 | 1201 | 2000 |
| Catalysis by hen egg-white lysozyme proceeds via a covalent intermediate DJ Vocadlo, GJ Davies, R Laine, SG Withers Nature 412 (6849), 835-838, 2001 | 791 | 2001 |
| Glycosidase mechanisms CS Rye, SG Withers Current opinion in chemical biology 4 (5), 573-580, 2000 | 734 | 2000 |
| Glycosynthases: mutant glycosidases for oligosaccharide synthesis LF Mackenzie, Q Wang, RAJ Warren, SG Withers Journal of the American Chemical Society 120 (22), 5583-5584, 1998 | 711 | 1998 |
| X-ray structures along the reaction pathway of cyclodextrin glycosyltransferase elucidate catalysis in the α-amylase family J Uitdehaag, R Mosi, KH Kalk, BA van der Veen, L Dijkhuizen, SG Withers, ... nature structural biology 6 (5), 432-436, 1999 | 535 | 1999 |
| The structure of human pancreatic α‐amylase at 1.8 Å resolution and comparisons with related enzymes GD Brayer, Y Luo, SG Withers Protein Science 4 (9), 1730-1742, 1995 | 525 | 1995 |
| Crystal structure of the retaining galactosyltransferase LgtC from Neisseria meningitidis in complex with donor and acceptor sugar analogs K Persson, HD Ly, M Dieckelmann, WW Wakarchuk, SG Withers, ... Nature structural biology 8 (2), 166-175, 2001 | 475 | 2001 |
| Mechanism of Agrobacterium. beta.-glucosidase: kinetic studies JB Kempton, SG Withers Biochemistry 31 (41), 9961-9969, 1992 | 404 | 1992 |
| Crystallographic evidence for substrate-assisted catalysis in a bacterial β-hexosaminidase BL Mark, DJ Vocadlo, S Knapp, BL Triggs-Raine, SG Withers, ... Journal of Biological Chemistry 276 (13), 10330-10337, 2001 | 386 | 2001 |
| The pKa of the General Acid/Base Carboxyl Group of a Glycosidase Cycles during Catalysis: A 13C-NMR Study of Bacillus circulans Xylanase LP McIntosh, G Hand, PE Johnson, MD Joshi, M Körner, LA Plesniak, ... Biochemistry 35 (31), 9958-9966, 1996 | 381 | 1996 |
| NAG-thiazoline, an N-acetyl-β-hexosaminidase inhibitor that implicates acetamido participation S Knapp, D Vocadlo, Z Gao, B Kirk, J Lou, SG Withers Journal of the American Chemical Society 118 (28), 6804-6805, 1996 | 375 | 1996 |
| Mutagenesis of glycosidases HD Ly, SG Withers Annual review of biochemistry 68 (1), 487-522, 1999 | 365 | 1999 |
| Snapshots along an Enzymatic Reaction Coordinate: Analysis of a Retaining β-Glycoside Hydrolase, GJ Davies, L Mackenzie, A Varrot, M Dauter, AM Brzozowski, M Schülein, ... Biochemistry 37 (34), 11707-11713, 1998 | 341 | 1998 |
| Carbohydrate-active enzymes (CAZymes) in the gut microbiome JF Wardman, RK Bains, P Rahfeld, SG Withers Nature Reviews Microbiology 20 (9), 542-556, 2022 | 339 | 2022 |
| Engineering of glycosidases and glycosyltransferases SM Hancock, MD Vaughan, SG Withers Current opinion in chemical biology 10 (5), 509-519, 2006 | 331 | 2006 |
| Subsite Mapping of the Human Pancreatic α-Amylase Active Site through Structural, Kinetic, and Mutagenesis Techniques, GD Brayer, G Sidhu, R Maurus, EH Rydberg, C Braun, Y Wang, ... Biochemistry 39 (16), 4778-4791, 2000 | 319 | 2000 |
| Stereoselective hydrolysis catalyzed by related beta-1, 4-glucanases and beta-1, 4-xylanases. J Gebler, NR Gilkes, M Claeyssens, DB Wilson, P Beguin, ... Journal of Biological Chemistry 267 (18), 12559-12561, 1992 | 319 | 1992 |
| Unequivocal demonstration of the involvement of a glutamate residue as a nucleophile in the mechanism of a retaining glycosidase SG Withers, RAJ Warren, IP Street, K Rupitz, JB Kempton, R Aebersold Journal of the American Chemical Society 112 (15), 5887-5889, 1990 | 307 | 1990 |
| A Structural View of the Action of Escherichia coli (lacZ) β-Galactosidase, DH Juers, TD Heightman, A Vasella, JD McCarter, L Mackenzie, ... Biochemistry 40 (49), 14781-14794, 2001 | 298 | 2001 |
Warren WakarchukProfessor of Glycobiology, University of AlbertaE-mail confirmado em ualberta.ca
