Obserwuj
Martin Renatus
Martin Renatus
Associate Director, Novartis Pharma
Zweryfikowany adres z novartis.com
Tytuł
Cytowane przez
Cytowane przez
Rok
A unified model for apical caspase activation
KM Boatright, M Renatus, FL Scott, S Sperandio, H Shin, IM Pedersen, ...
Molecular cell 11 (2), 529-541, 2003
13912003
Structural basis for the inhibition of caspase-3 by XIAP
SJ Riedl, M Renatus, R Schwarzenbacher, Q Zhou, C Sun, SW Fesik, ...
Cell 104 (5), 791-800, 2001
11012001
Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus
P Erbel, N Schiering, A D'Arcy, M Renatus, M Kroemer, SP Lim, Z Yin, ...
Nature structural & molecular biology 13 (4), 372-373, 2006
6682006
Dimer formation drives the activation of the cell death protease caspase 9
M Renatus, HR Stennicke, FL Scott, RC Liddington, GS Salvesen
Proceedings of the National Academy of Sciences 98 (25), 14250-14255, 2001
6512001
Crystal structure of the anthrax lethal factor
AD Pannifer, TY Wong, R Schwarzenbacher, M Renatus, C Petosa, ...
Nature 414 (6860), 229-233, 2001
5652001
XIAP inhibits caspase‐3 and‐7 using two binding sites: evolutionarily conserved mechanism of IAPs
FL Scott, JB Denault, SJ Riedl, H Shin, M Renatus, GS Salvesen
The EMBO journal 24 (3), 645-655, 2005
5432005
Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8
HR Stennicke, M RENATUS, M MELDAL, GS SALVESEN
Biochemical Journal 350 (2), 563-568, 2000
3812000
Structural basis for the activation of human procaspase-7
SJ Riedl, P Fuentes-Prior, M Renatus, N Kairies, S Krapp, R Huber, ...
Proceedings of the National Academy of Sciences 98 (26), 14790-14795, 2001
2922001
Crystal structure of the human COP9 signalosome
GM Lingaraju, RD Bunker, S Cavadini, D Hess, U Hassiepen, M Renatus, ...
Nature 512 (7513), 161-165, 2014
2492014
Structural basis of ubiquitin recognition by the deubiquitinating protease USP2
M Renatus, SG Parrado, A D'Arcy, U Eidhoff, B Gerhartz, U Hassiepen, ...
Structure 14 (8), 1293-1302, 2006
2452006
Targeted inhibition of the COP9 signalosome for treatment of cancer
A Schlierf, E Altmann, J Quancard, AB Jefferson, R Assenberg, M Renatus, ...
Nature communications 7 (1), 13166, 2016
1602016
Apoptosome: the seven-spoked death machine
GS Salvesen, M Renatus
Developmental Cell 2 (3), 256-257, 2002
1512002
Lysine 156 promotes the anomalous proenzyme activity of tPA: X‐ray crystal structure of single‐chain human tPA
M Renatus, RA Engh, MT Stubbs, R Huber, S Fischer, U Kohnert, W Bode
The EMBO journal, 1997
1421997
Structural and functional analyses of benzamidine-based inhibitors in complex with trypsin: implications for the inhibition of factor Xa, tPA, and urokinase
M Renatus, W Bode, R Huber, J Stuerzebecher, MT Stubbs
Journal of medicinal chemistry 41 (27), 5445-5456, 1998
1401998
Structural determinants of MALT1 protease activity
C Wiesmann, L Leder, J Blank, A Bernardi, S Melkko, A Decock, A D'Arcy, ...
Journal of molecular biology 419 (1-2), 4-21, 2012
1042012
Structural mapping of the active site specificity determinants of human tissue-type plasminogen activator: implications for the design of low molecular weight substrates and …
M Renatus, W Bode, R Huber, J Stürzebecher, D Prasa, S Fischer, ...
Journal of Biological Chemistry 272 (35), 21713-21719, 1997
921997
3-Amidinophenylalanine-based inhibitors of urokinase
J Stürzebecher, H Vieweg, T Steinmetzer, A Schweinitz, MT Stubbs, ...
Bioorganic & medicinal chemistry letters 9 (21), 3147-3152, 1999
851999
The BIR domain of IAP-like protein 2 is conformationally unstable: implications for caspase inhibition
H Shin, M Renatus, BP Eckelman, VA Nunes, CAM Sampaio, ...
Biochemical Journal 385 (1), 1-10, 2005
832005
Structural basis of BRCC36 function in DNA repair and immune regulation
J Rabl, RD Bunker, AD Schenk, S Cavadini, ME Gill, W Abdulrahman, ...
Molecular cell 75 (3), 483-497. e9, 2019
662019
An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient
J Quancard, T Klein, SY Fung, M Renatus, N Hughes, L Israël, JJ Priatel, ...
Nature chemical biology 15 (3), 304-313, 2019
652019
Nie można teraz wykonać tej operacji. Spróbuj ponownie później.
Prace 1–20