Structure of signaling-competent neurotensin receptor 1 obtained by directed evolution in Escherichia coli P Egloff, M Hillenbrand, C Klenk, A Batyuk, P Heine, S Balada, ... Proceedings of the National Academy of Sciences 111 (6), E655-E662, 2014 | 262 | 2014 |
The role of insulin 3, testosterone, Müllerian inhibiting substance and relaxin in rat gubernacular growth Y Kubota, C Temelcos, RAD Bathgate, KJ Smith, D Scott, C Zhao, ... Molecular human reproduction 8 (10), 900-905, 2002 | 192 | 2002 |
Characterization of novel splice variants of LGR7 and LGR8 reveals that receptor signaling is mediated by their unique low density lipoprotein class A modules DJ Scott, S Layfield, Y Yan, S Sudo, AJW Hsueh, GW Tregear, ... Journal of Biological Chemistry 281 (46), 34942-34954, 2006 | 162 | 2006 |
SYT1-associated neurodevelopmental disorder: a case series K Baker, SL Gordon, H Melland, F Bumbak, DJ Scott, TJ Jiang, D Owen, ... Brain 141 (9), 2576-2591, 2018 | 126 | 2018 |
Stabilizing membrane proteins through protein engineering DJ Scott, L Kummer, D Tremmel, A Plückthun Current opinion in chemical biology 17 (3), 427-435, 2013 | 107 | 2013 |
A novel ultra-stable, monomeric green fluorescent protein for direct volumetric imaging of whole organs using CLARITY DJ Scott, NJ Gunn, KJ Yong, VC Wimmer, NA Veldhuis, LM Challis, ... Scientific reports 8 (1), 667, 2018 | 96 | 2018 |
Direct molecular evolution of detergent-stable G protein-coupled receptors using polymer encapsulated cells DJ Scott, A Plückthun Journal of molecular biology 425 (3), 662-677, 2013 | 85 | 2013 |
Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3 KJ Rosengren, S Zhang, F Lin, NL Daly, DJ Scott, RA Hughes, ... Journal of Biological Chemistry 281 (38), 28287-28295, 2006 | 79 | 2006 |
Characterization of the rat INSL3 receptor DJ Scott, P Fu, PJ Shen, A Gundlach, S Layfield, A Riesewijk, ... Annals of the New York Academy of Sciences 1041 (1), 13-16, 2005 | 64 | 2005 |
Defining the LGR8 residues involved in binding insulin-like peptide 3 DJ Scott, TN Wilkinson, S Zhang, T Ferraro, JD Wade, GW Tregear, ... Molecular Endocrinology 21 (7), 1699-1712, 2007 | 63 | 2007 |
The complex binding mode of the peptide hormone H2 relaxin to its receptor RXFP1 A Sethi, S Bruell, N Patil, MA Hossain, DJ Scott, EJ Petrie, RAD Bathgate, ... Nature communications 7 (1), 11344, 2016 | 56 | 2016 |
Identification and characterization of the mouse and rat relaxin receptors as the novel orthologues of human leucine-rich repeat-containing G-protein-coupled receptor 7. DJ Scott, S Layfield, A Riesewijk, H Morita, GW Tregear, RAD Bathgate Clinical & Experimental Pharmacology & Physiology 31 (11), 2004 | 52 | 2004 |
The Different Ligand-Binding Modes of Relaxin Family Peptide Receptors RXFP1 and RXFP2 DJ Scott, KJ Rosengren, RAD Bathgate Molecular Endocrinology, 2012 | 50 | 2012 |
Improving the apo-state detergent stability of NTS1 with CHESS for pharmacological and structural studies DJ Scott, L Kummer, P Egloff, RAD Bathgate, A Plückthun Biochimica et Biophysica Acta (BBA)-Biomembranes 1838 (11), 2817-2824, 2014 | 45 | 2014 |
Identification of the N-linked glycosylation sites of the human relaxin receptor and effect of glycosylation on receptor function Y Yan, DJ Scott, TN Wilkinson, J Ji, GW Tregear, RAD Bathgate Biochemistry 47 (26), 6953-6968, 2008 | 43 | 2008 |
Optimization and 13CH3 methionine labeling of a signaling competent neurotensin receptor 1 variant for NMR studies F Bumbak, AC Keen, NJ Gunn, PR Gooley, RAD Bathgate, DJ Scott Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (6), 1372-1383, 2018 | 40 | 2018 |
LGR7‐Truncate Is a Splice Variant of the Relaxin Receptor LGR7 and Is a Relaxin Antagonist in Vitro DJ Scott, GW Tregear, RAD Bathgate Annals of the New York Academy of Sciences 1041 (1), 22-26, 2005 | 38 | 2005 |
Determinants of Ligand Subtype-Selectivity at α1A-Adrenoceptor Revealed Using Saturation Transfer Difference (STD) NMR KJ Yong, TM Vaid, PJ Shilling, FJ Wu, LM Williams, M Deluigi, ... ACS chemical biology 13 (4), 1090-1102, 2018 | 37 | 2018 |
The relaxin receptor as a therapeutic target–perspectives from evolution and drug targeting RAD Bathgate, M Kocan, DJ Scott, MA Hossain, SV Good, S Yegorov, ... Pharmacology & therapeutics 187, 114-132, 2018 | 36 | 2018 |
Characterization of the mouse and rat relaxin receptors DJ Scott, S Layfield, A Riesewijk, H Morita, GW Tregear, RAD Bathgate Annals of the New York Academy of Sciences 1041 (1), 8-12, 2005 | 36 | 2005 |