| Bepridil is potent against SARS-CoV-2 in vitro EC Vatansever, KS Yang, AK Drelich, KC Kratch, CC Cho, KR Kempaiah, ... Proceedings of the National Academy of Sciences 118 (10), e2012201118, 2021 | 107 | 2021 |
| Drug repurposing for the SARS‐CoV‐2 papain‐like protease CC Cho, SG Li, TJ Lalonde, KS Yang, G Yu, Y Qiao, S Xu, W Ray Liu ChemMedChem 17 (1), e202100455, 2022 | 44 | 2022 |
| Evaluation of SARS-CoV-2 main protease inhibitors using a novel cell-based assay W Cao, CCD Cho, ZZ Geng, N Shaabani, XR Ma, EC Vatansever, ... ACS central science 8 (2), 192-204, 2022 | 43 | 2022 |
| A multi-pronged evaluation of aldehyde-based tripeptidyl main protease inhibitors as SARS-CoV-2 antivirals Y Ma, KS Yang, ZZ Geng, YR Alugubelli, N Shaabani, EC Vatansever, ... European Journal of Medicinal Chemistry 240, 114570, 2022 | 37 | 2022 |
| A systematic exploration of boceprevir-based main protease inhibitors as SARS-CoV-2 antivirals YR Alugubelli, ZZ Geng, KS Yang, N Shaabani, K Khatua, XR Ma, ... European Journal of Medicinal Chemistry 240, 114596, 2022 | 36 | 2022 |
| Targeting the SARS-CoV-2 main protease to repurpose drugs for COVID-19 EC Vatansever, KS Yang, KC Kratch, A Drelich, CC Cho, DM Mellott, S Xu, ... | 34 | 2020 |
| A systematic survey of reversibly covalent dipeptidyl inhibitors of the SARS-CoV-2 main protease ZZ Geng, S Atla, N Shaabani, V Vulupala, KS Yang, YR Alugubelli, ... Journal of medicinal chemistry 66 (16), 11040-11055, 2023 | 18 | 2023 |
| The pyrrolysyl-tRNA synthetase activity can be improved by a P188 mutation that stabilizes the full-length enzyme CC Cho, LR Blankenship, X Ma, S Xu, W Liu Journal of molecular biology 434 (8), 167453, 2022 | 14 | 2022 |
| Stable nuclei of nucleoprotein filament and high ssDNA binding affinity contribute to enhanced RecA E38K recombinase activity CH Lu, TT Chang, CC Cho, HC Lin, HW Li Scientific Reports 7 (1), 14964, 2017 | 9 | 2017 |
| An enhanced hybrid screening approach to identify potent inhibitors for the SARS-CoV-2 main protease from the NCI compound library SG Li, KS Yang, LR Blankenship, CCD Cho, S Xu, H Wang, WR Liu Frontiers in Chemistry 10, 816576, 2022 | 8 | 2022 |
| Cellular activities of SARS-CoV-2 main protease inhibitors reveal their unique characteristics W Cao, CCD Cho, ZZ Geng, XR Ma, R Allen, N Shaabani, EC Vatansever, ... bioRxiv, 2021.06. 08.447613, 2021 | 8 | 2021 |
| Azapeptides with unique covalent warheads as SARS-CoV-2 main protease inhibitors K Khatua, YR Alugubelli, KS Yang, VR Vulupala, LR Blankenship, ... Antiviral Research 225, 105874, 2024 | 5 | 2024 |
| An amber-encoding helper phage for more efficient phage display of noncanonical amino acids JT Hampton, CCD Cho, DD Coleman, ZZ Geng, PHC Chen, GK Dubey, ... Nucleic Acids Research 51 (13), 6566-6577, 2023 | 5 | 2023 |
| The N-Terminal Carbamate is Key to High Cellular and Antiviral Potency for Boceprevir-Based SARS-CoV-2 Main Protease Inhibitors YR Alugubelli, ZZ Geng, KS Yang, N Shaabani, K Khatua, XR Ma, ... BioRxiv, 2021.12. 18.473330, 2021 | 5 | 2021 |
| How Chi Sequence Modifies RecBCD Single‐Stranded DNA Translocase Activity CC Cho, C Chung, HW Li Chemphyschem 19 (2), 243-247, 2018 | 5 | 2018 |
| The P3 O-Tert-Butyl-Threonine is Key to High Cellular and Antiviral Potency for Aldehyde-Based SARS-CoV-2 Main Protease Inhibitors Y Ma, KS Yang, ZZ Geng, YR Alugubelli, N Shaabani, EC Vatansever, ... bioRxiv, 2021.12. 18.473326, 2021 | 4 | 2021 |
| Sars-cov-2 main protease inhibitors W Liu, CA Fierke, S Xu, K Yang, X Ma, MA Yuying, YR Alugubelli, ... US Patent App. 17/719,870, 2022 | 3 | 2022 |
| SARS-CoV-2 Main Protease Inhibitors That Leverage Unique Interactions with the Solvent Exposed S3 Site of the Enzyme LR Blankenship, KS Yang, VR Vulupala, YR Alugubelli, K Khatua, ... ACS Medicinal Chemistry Letters 15 (6), 950-957, 2024 | 2 | 2024 |
| An Azapeptide Platform in Conjunction with Covalent Warheads to Uncover High-Potency Inhibitors for SARS-CoV-2 Main Protease K Khatua, YR Alugubelli, KS Yang, VR Vulupala, LR Blankenship, ... bioRxiv, 2023.04. 11.536467, 2023 | 2 | 2023 |
| Directed Evolution of Candidatus Methanomethylophilus alvus Pyrrolysyl-tRNA Synthetase for the Genetic Incorporation of Two Different Noncanonical Amino … CCD Cho, WM Leeuwon, WR Liu ACS bio & med Chem Au 4 (5), 233-241, 2024 | | 2024 |
