Metabolic instruction of immunity MD Buck, RT Sowell, SM Kaech, EL Pearce Cell 169 (4), 570-586, 2017 | 1102 | 2017 |
Impaired HLA class I antigen processing and presentation as a mechanism of acquired resistance to immune checkpoint inhibitors in lung cancer S Gettinger, J Choi, K Hastings, A Truini, I Datar, R Sowell, A Wurtz, ... Cancer discovery 7 (12), 1420-1435, 2017 | 705 | 2017 |
Persistent antigen at vaccination sites induces tumor-specific CD8+ T cell sequestration, dysfunction and deletion Y Hailemichael, Z Dai, N Jaffarzad, Y Ye, MA Medina, XF Huang, ... Nature medicine 19 (4), 465-472, 2013 | 511 | 2013 |
A dormant TIL phenotype defines non-small cell lung carcinomas sensitive to immune checkpoint blockers SN Gettinger, J Choi, N Mani, MF Sanmamed, I Datar, R Sowell, VY Du, ... Nature communications 9 (1), 3196, 2018 | 178 | 2018 |
Cutting edge: generation of effector cells that localize to mucosal tissues and form resident memory CD8 T cells is controlled by mTOR RT Sowell, M Rogozinska, CE Nelson, V Vezys, AL Marzo The Journal of Immunology 193 (5), 2067-2071, 2014 | 80 | 2014 |
Effects of cryopreservation on effector cells for antibody dependent cell-mediated cytotoxicity (ADCC) and natural killer (NK) cell activity in 51Cr-release and CD107a assays MM Mata, F Mahmood, RT Sowell, LL Baum Journal of immunological methods 406, 1-9, 2014 | 76 | 2014 |
The CD8+ memory T-cell state of readiness is actively maintained and reversible A Allam, DB Conze, ML Giardino Torchia, I Munitic, H Yagita, RT Sowell, ... Blood, The Journal of the American Society of Hematology 114 (10), 2121-2130, 2009 | 57 | 2009 |
IL-15 complexes induce migration of resting memory CD8 T cells into mucosal tissues RT Sowell, JW Goldufsky, M Rogozinska, Z Quiles, Y Cao, EF Castillo, ... The Journal of Immunology 199 (7), 2536-2546, 2017 | 55 | 2017 |
Impaired HLA class I antigen processing and presentation as a mechanism of acquired resistance to immune checkpoint inhibitors in lung cancer. Cancer Discov 7: 1420–1435 S Gettinger, J Choi, K Hastings, A Truini, I Datar, R Sowell, A Wurtz, ... CD-17-0593, 2017 | 28 | 2017 |
Non-oncogenic acute viral infections disrupt anti-cancer responses and lead to accelerated cancer-specific host death FJ Kohlhapp, EJ Huelsmann, AT Lacek, JM Schenkel, J Lusciks, ... Cell reports 17 (4), 957-965, 2016 | 28 | 2016 |
2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) reduces Leishmania major burdens in C57BL/6 mice OJ Bowers, KB Sommersted, RT Sowell, GE Boling, WH Hanneman, ... The American journal of tropical medicine and hygiene 75 (4), 749-752, 2006 | 23 | 2006 |
Probing the diversity of T cell dysfunction in cancer RT Sowell, SM Kaech Cell 166 (6), 1362-1364, 2016 | 18 | 2016 |
Resident-memory CD8 T cells and mTOR: generation, protection, and clinical importance RT Sowell, AL Marzo Frontiers in Immunology 6, 38, 2015 | 13 | 2015 |
Exploring single-cell data with multitasking deep neural networks M Amodio, K Srinivasan, D van Dijk, H Mohsen, K Yim, R Muhle, ... BioRxiv, 237065, 2017 | 9 | 2017 |
Final results of a phase I prospective trial evaluating the combination of stereotactic body radiotherapy (SBRT) with concurrent pembrolizumab in patients with metastatic non … AM Campbell, RS Herbst, SN Gettinger, SB Goldberg, HM Kluger, ... Journal of Clinical Oncology 36 (15_suppl), 9099-9099, 2018 | 8 | 2018 |
The role of precursor frequency in the differentiation of memory T cells: memory by numbers AL Marzo, RT Sowell, B Scott Memory T Cells, 69-78, 2010 | 3 | 2010 |
A phase I trial of intratumoral STX-001: A novel self-replicating mRNA expressing IL-12 alone or with pembrolizumab in advanced solid tumors. JJ Luke, LC Kennedy, N Sankar, AM Menzies, ACJ van Akkooi, ... Journal of Clinical Oncology 42 (16_suppl), TPS2696-TPS2696, 2024 | 1 | 2024 |
STX-001, a locally administered LNP-formulated self-replicating mRNA that encodes the therapeutic payload IL-12, induces deep systemic immune responses to solid tumors RT Sowell, JS Khurana, Z Su, W Zhao, GN Shenoy, M Dey, AC Lemaire, ... Cancer Research 83 (7_Supplement), 2731-2731, 2023 | 1 | 2023 |
Signaling through Tsc2-mTOR regulates memory CD8 T cell differentiation.(LYM4P. 755) R Sowell, M Rogozinska, A Marzo The Journal of Immunology 192 (1_Supplement), 65.12-65.12, 2014 | 1 | 2014 |
1328 STX-003: utilizing programmable genetic circuits for tumor-specific IL-12 expression and reduced toxicity with systemically delivered mRNA GN Shenoy, WA Tseng, EA Clinton, RA Patenaude, W Abraham, Z Su, ... Journal for ImmunoTherapy of Cancer 12 (Suppl 2), 2024 | | 2024 |