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Ryan Sowell
Ryan Sowell
Director, Strand Therapeutics
Zweryfikowany adres z strandtx.com - Strona główna
Tytuł
Cytowane przez
Cytowane przez
Rok
Metabolic instruction of immunity
MD Buck, RT Sowell, SM Kaech, EL Pearce
Cell 169 (4), 570-586, 2017
11022017
Impaired HLA class I antigen processing and presentation as a mechanism of acquired resistance to immune checkpoint inhibitors in lung cancer
S Gettinger, J Choi, K Hastings, A Truini, I Datar, R Sowell, A Wurtz, ...
Cancer discovery 7 (12), 1420-1435, 2017
7052017
Persistent antigen at vaccination sites induces tumor-specific CD8+ T cell sequestration, dysfunction and deletion
Y Hailemichael, Z Dai, N Jaffarzad, Y Ye, MA Medina, XF Huang, ...
Nature medicine 19 (4), 465-472, 2013
5112013
A dormant TIL phenotype defines non-small cell lung carcinomas sensitive to immune checkpoint blockers
SN Gettinger, J Choi, N Mani, MF Sanmamed, I Datar, R Sowell, VY Du, ...
Nature communications 9 (1), 3196, 2018
1782018
Cutting edge: generation of effector cells that localize to mucosal tissues and form resident memory CD8 T cells is controlled by mTOR
RT Sowell, M Rogozinska, CE Nelson, V Vezys, AL Marzo
The Journal of Immunology 193 (5), 2067-2071, 2014
802014
Effects of cryopreservation on effector cells for antibody dependent cell-mediated cytotoxicity (ADCC) and natural killer (NK) cell activity in 51Cr-release and CD107a assays
MM Mata, F Mahmood, RT Sowell, LL Baum
Journal of immunological methods 406, 1-9, 2014
762014
The CD8+ memory T-cell state of readiness is actively maintained and reversible
A Allam, DB Conze, ML Giardino Torchia, I Munitic, H Yagita, RT Sowell, ...
Blood, The Journal of the American Society of Hematology 114 (10), 2121-2130, 2009
572009
IL-15 complexes induce migration of resting memory CD8 T cells into mucosal tissues
RT Sowell, JW Goldufsky, M Rogozinska, Z Quiles, Y Cao, EF Castillo, ...
The Journal of Immunology 199 (7), 2536-2546, 2017
552017
Impaired HLA class I antigen processing and presentation as a mechanism of acquired resistance to immune checkpoint inhibitors in lung cancer. Cancer Discov 7: 1420–1435
S Gettinger, J Choi, K Hastings, A Truini, I Datar, R Sowell, A Wurtz, ...
CD-17-0593, 2017
282017
Non-oncogenic acute viral infections disrupt anti-cancer responses and lead to accelerated cancer-specific host death
FJ Kohlhapp, EJ Huelsmann, AT Lacek, JM Schenkel, J Lusciks, ...
Cell reports 17 (4), 957-965, 2016
282016
2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) reduces Leishmania major burdens in C57BL/6 mice
OJ Bowers, KB Sommersted, RT Sowell, GE Boling, WH Hanneman, ...
The American journal of tropical medicine and hygiene 75 (4), 749-752, 2006
232006
Probing the diversity of T cell dysfunction in cancer
RT Sowell, SM Kaech
Cell 166 (6), 1362-1364, 2016
182016
Resident-memory CD8 T cells and mTOR: generation, protection, and clinical importance
RT Sowell, AL Marzo
Frontiers in Immunology 6, 38, 2015
132015
Exploring single-cell data with multitasking deep neural networks
M Amodio, K Srinivasan, D van Dijk, H Mohsen, K Yim, R Muhle, ...
BioRxiv, 237065, 2017
92017
Final results of a phase I prospective trial evaluating the combination of stereotactic body radiotherapy (SBRT) with concurrent pembrolizumab in patients with metastatic non …
AM Campbell, RS Herbst, SN Gettinger, SB Goldberg, HM Kluger, ...
Journal of Clinical Oncology 36 (15_suppl), 9099-9099, 2018
82018
The role of precursor frequency in the differentiation of memory T cells: memory by numbers
AL Marzo, RT Sowell, B Scott
Memory T Cells, 69-78, 2010
32010
A phase I trial of intratumoral STX-001: A novel self-replicating mRNA expressing IL-12 alone or with pembrolizumab in advanced solid tumors.
JJ Luke, LC Kennedy, N Sankar, AM Menzies, ACJ van Akkooi, ...
Journal of Clinical Oncology 42 (16_suppl), TPS2696-TPS2696, 2024
12024
STX-001, a locally administered LNP-formulated self-replicating mRNA that encodes the therapeutic payload IL-12, induces deep systemic immune responses to solid tumors
RT Sowell, JS Khurana, Z Su, W Zhao, GN Shenoy, M Dey, AC Lemaire, ...
Cancer Research 83 (7_Supplement), 2731-2731, 2023
12023
Signaling through Tsc2-mTOR regulates memory CD8 T cell differentiation.(LYM4P. 755)
R Sowell, M Rogozinska, A Marzo
The Journal of Immunology 192 (1_Supplement), 65.12-65.12, 2014
12014
1328 STX-003: utilizing programmable genetic circuits for tumor-specific IL-12 expression and reduced toxicity with systemically delivered mRNA
GN Shenoy, WA Tseng, EA Clinton, RA Patenaude, W Abraham, Z Su, ...
Journal for ImmunoTherapy of Cancer 12 (Suppl 2), 2024
2024
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