Lipid-induced toxicity stimulates hepatocytes to release angiogenic microparticles that require Vanin-1 for uptake by endothelial cells D Povero, A Eguchi, IR Niesman, N Andronikou, X de Mollerat du Jeu, ... Science signaling 6 (296), ra88-ra88, 2013 | 242 | 2013 |
Transient prenatal androgen exposure produces metabolic syndrome in adult female rats M Demissie, M Lazic, EM Foecking, F Aird, A Dunaif, JE Levine American Journal of Physiology-Endocrinology and Metabolism 295 (2), E262-E268, 2008 | 177 | 2008 |
Circulating adipocyte-derived extracellular vesicles are novel markers of metabolic stress A Eguchi, M Lazic, AM Armando, SA Phillips, R Katebian, S Maraka, ... Journal of molecular medicine 94, 1241-1253, 2016 | 176 | 2016 |
Genetic rescue of nonclassical ERα signaling normalizes energy balance in obese Erα-null mutant mice CJ Park, Z Zhao, C Glidewell-Kenney, M Lazic, P Chambon, A Krust, ... The Journal of clinical investigation 121 (2), 604-612, 2011 | 173 | 2011 |
Microparticles release by adipocytes act as “find-me” signals to promote macrophage migration A Eguchi, A Mulya, M Lazic, D Radhakrishnan, MP Berk, D Povero, ... PloS one 10 (4), e0123110, 2015 | 120 | 2015 |
Reduced dietary omega-6 to omega-3 fatty acid ratio and 12/15-lipoxygenase deficiency are protective against chronic high fat diet-induced steatohepatitis M Lazic, ME Inzaugarat, D Povero, IC Zhao, M Chen, M Nalbandian, ... PloS one 9 (9), e107658, 2014 | 76 | 2014 |
Redox nanoparticles as a novel treatment approach for inflammation and fibrosis associated with nonalcoholic steatohepatitis A Eguchi, T Yoshitomi, M Lazic, CD Johnson, LB Vong, A Wree, D Povero, ... Nanomedicine 10 (17), 2697-2708, 2015 | 52 | 2015 |
Overcoming Preclinical Safety Obstacles to Discover (S)-N-((1, 2, 3, 5, 6, 7-Hexahydro-s-indacen-4-yl) carbamoyl)-6-(methylamino)-6, 7-dihydro-5 H-pyrazolo [5, 1-b][1, 3 … C McBride, L Trzoss, D Povero, M Lazic, G Ambrus-Aikelin, A Santini, ... Journal of Medicinal Chemistry 65 (21), 14721-14739, 2022 | 50 | 2022 |
Prenatal androgen treatment alters body composition and glucose homeostasis in male rats M Lazic, F Aird, JE Levine, A Dunaif The Journal of endocrinology 208 (3), 293, 2010 | 39 | 2010 |
Differential regulation of inflammation and apoptosis in Fas-resistant hepatocyte-specific Bid-deficient mice M Lazic, A Eguchi, MP Berk, D Povero, B Papouchado, A Mulya, ... Journal of hepatology 61 (1), 107-115, 2014 | 17 | 2014 |
JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders G Ambrus-Aikelin, K Takeda, A Joetham, M Lazic, D Povero, AM Santini, ... Scientific Reports 13 (1), 13524, 2023 | 13 | 2023 |
Pharmacology of a potent and novel inhibitor of the NOD-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome that attenuates development of nonalcoholic … D Povero, M Lazic, C McBride, G Ambrus-Aikelin, R Stansfield, ... The Journal of Pharmacology and Experimental Therapeutics 386 (2), 242-258, 2023 | 7 | 2023 |
Hepatocytes release microparticles during lipotoxicity that have potent pro-angiogenic effects in vitro and in vivo through Vanin-1-dependent internalization: 116 D Povero, A Eguchi, M Lazic, C Johnson, M Parola, A Feldstein Hepatology 56, 251A, 2012 | 2 | 2012 |
Discovery of Inhibitors of NLRP3 inflammasome assembly for the treatment of NASH and liver fibrosis J Veal, C Mcbride, M Lazic, D Povero, G Ambrus, A Santini, R Stansfield, ... Journal of Hepatology 68, S347-S348, 2018 | 1 | 2018 |
1271 REDUCED DIETARY OMEGA-6: OMEGA-3 RATIO AND 12/15-LIPOXYGENASE DEFICIENCY PROTECT FROM HIGH FAT DIET-INDUCED STEATOHEPATITIS M Lazic, E Inzaugarat, D Povero, I Chen, M Chen, M Nalbandyan, ... Journal of Hepatology 58, S514, 2013 | 1 | 2013 |
Hepatocyte-derived microparticles with a specific antigenic composition are released in blood during Nash development: implications for biomarkers development D Povero, A Eguchi, C Johnson, A Wree, M Lazic, M Parola, AE Feldstein Journal of Hepatology, S34-S34, 2013 | 1 | 2013 |
Author Correction: JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders G Ambrus-Aikelin, K Takeda, A Joetham, M Lazic, D Povero, AM Santini, ... Scientific Reports 13, 20081, 2023 | | 2023 |
Perilipin a is a Novel Biomarker of Circulating Adipocyte-Derived Extracellular Vesicles in Both Murine Models of Obesity and Obese Humans A Eguchi, M Lazic, AM Armando, SA Phillips, O Quehenberger, DD Sears, ... Journal of Hepatology 64 (2), S672-S673, 2016 | | 2016 |
Circulating extracellular vesicles with a specific Proteome and liver microRNAs are novel biomarkers for liver injury in fatty liver disease: 1095 D Povero, A Eguchi, H Li, C Johnson, A Wree, M Lazic, K Messer, ... Hepatology 60, 733A, 2014 | | 2014 |
P274 MICROPARTICLES FROM HYPERTROPHIED ADIPOCYTES OR OBESE MICE ACTIVATE MONOCYTES AND MACROPHAGES CONTRIBUTING TO LIVER INFLAMMATION A Eguchi, M Lazic, A Mulya, MP Berk, A Gornicka, SA Phillips, DD Sears, ... Journal of Hepatology 60 (1), S157, 2014 | | 2014 |