Artykuły udostępnione publicznie: - Hilal LashuelWięcej informacji
Niedostępne w żadnym miejscu: 2
Elucidating the role of site-specific nitration of α-synuclein in the pathogenesis of Parkinson’s disease via protein semisynthesis and mutagenesis
R Burai, N Ait-Bouziad, A Chiki, HA Lashuel
Journal of the American Chemical Society 137 (15), 5041-5052, 2015
Upoważnienia: Swiss National Science Foundation, European Commission
Wechselwirkungen zwischen amyloidogenen Proteinen und Membranen: Modellsysteme liefern mechanistische Einblicke
SM Butterfield, HA Lashuel
Angewandte Chemie 122 (33), 5760-5788, 2010
Upoważnienia: Swiss National Science Foundation
Dostępne w jakimś miejscu: 133
The many faces of α-synuclein: from structure and toxicity to therapeutic target
HA Lashuel, CR Overk, A Oueslati, E Masliah
Nature Reviews Neuroscience 14 (1), 38-48, 2013
Upoważnienia: Swiss National Science Foundation, US National Institutes of Health
Amyloidogenic protein–membrane interactions: mechanistic insight from model systems
SM Butterfield, HA Lashuel
Angewandte Chemie International Edition 49 (33), 5628-5654, 2010
Upoważnienia: Swiss National Science Foundation
α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer
B Fauvet, MK Mbefo, MB Fares, C Desobry, S Michael, MT Ardah, E Tsika, ...
Journal of Biological Chemistry 287 (19), 15345-15364, 2012
Upoważnienia: Swiss National Science Foundation, US National Institutes of Health
Half a century of amyloids: past, present and future
PC Ke, R Zhou, LC Serpell, R Riek, TPJ Knowles, HA Lashuel, E Gazit, ...
Chemical Society Reviews 49 (15), 5473-5509, 2020
Upoważnienia: US National Science Foundation, US National Institutes of Health, Howard …
Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of α-synuclein
KE Paleologou, AW Schmid, CC Rospigliosi, HY Kim, GR Lamberto, ...
Journal of Biological Chemistry 283 (24), 16895-16905, 2008
Upoważnienia: Swiss National Science Foundation, US National Institutes of Health, German …
Phosphorylation at S87 is enhanced in synucleinopathies, inhibits α-synuclein oligomerization, and influences synuclein-membrane interactions
KE Paleologou, A Oueslati, G Shakked, CC Rospigliosi, HY Kim, ...
Journal of Neuroscience 30 (9), 3184-3198, 2010
Upoważnienia: Swiss National Science Foundation, US National Institutes of Health, German …
The ratio of monomeric to aggregated forms of Aβ40 and Aβ42 is an important determinant of amyloid-β aggregation, fibrillogenesis, and toxicity
A Jan, O Gokce, R Luthi-Carter, HA Lashuel
Journal of Biological Chemistry 283 (42), 28176-28189, 2008
Upoważnienia: Swiss National Science Foundation
Amyloid-β aggregates cause alterations of astrocytic metabolic phenotype: impact on neuronal viability
I Allaman, M Gavillet, M Bélanger, T Laroche, D Viertl, HA Lashuel, ...
Journal of Neuroscience 30 (9), 3326-3338, 2010
Upoważnienia: Swiss National Science Foundation, Fonds de recherche du Québec - Santé
Phosphorylation of synucleins by members of the Polo-like kinase family
MK Mbefo, KE Paleologou, A Boucharaba, A Oueslati, H Schell, ...
Journal of Biological Chemistry 285 (4), 2807-2822, 2010
Upoważnienia: Swiss National Science Foundation, German Research Foundation
Preparation and characterization of toxic Aβ aggregates for structural and functional studies in Alzheimer's disease research
A Jan, DM Hartley, HA Lashuel
Nature protocols 5 (6), 1186-1209, 2010
Upoważnienia: Swiss National Science Foundation, US National Institutes of Health
The novel Parkinson's disease linked mutation G51D attenuates in vitro aggregation and membrane binding of α-synuclein, and enhances its secretion and nuclear …
MB Fares, N Ait-Bouziad, I Dikiy, MK Mbefo, A Jovičić, A Kiely, JL Holton, ...
Human molecular genetics 23 (17), 4491-4509, 2014
Upoważnienia: Swiss National Science Foundation, US National Institutes of Health
Highly efficient and chemoselective peptide ubiquitylation
KS Ajish Kumar, M Haj-Yahya, D Olschewski, HA Lashuel, A Brik
Angewandte Chemie (International ed. in English) 48 (43), 8090-4, 2009
Upoważnienia: Swiss National Science Foundation
c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's disease
AL Mahul-Mellier, B Fauvet, A Gysbers, I Dikiy, A Oueslati, S Georgeon, ...
Human molecular genetics 23 (11), 2858-2879, 2014
Upoważnienia: Swiss National Science Foundation, US National Institutes of Health …
Structural properties of pore-forming oligomers of α-synuclein
HY Kim, MK Cho, A Kumar, E Maier, C Siebenhaar, S Becker, ...
Journal of the American Chemical Society 131 (47), 17482-17489, 2009
Upoważnienia: German Research Foundation
Resolving molecule-specific information in dynamic lipid membrane processes with multi-resonant infrared metasurfaces
D Rodrigo, A Tittl, N Ait-Bouziad, A John-Herpin, O Limaj, C Kelly, D Yoo, ...
Nature communications 9 (1), 2160, 2018
Upoważnienia: European Commission
Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivo
A Oueslati, BL Schneider, P Aebischer, HA Lashuel
Proceedings of the National Academy of Sciences 110 (41), E3945-E3954, 2013
Upoważnienia: Swiss National Science Foundation
Hsp104 antagonizes α-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson disease
CL Bianco, J Shorter, E Régulier, H Lashuel, T Iwatsubo, S Lindquist, ...
The Journal of clinical investigation 118 (9), 3087-3097, 2008
Upoważnienia: Swiss National Science Foundation, US National Institutes of Health
Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies
H Vicente Miranda, ÉM Szegő, LMA Oliveira, C Breda, E Darendelioglu, ...
Brain 140 (5), 1399-1419, 2017
Upoważnienia: German Research Foundation, Fundação para a Ciência e a Tecnologia, Portugal …
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