Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes M Solimena, AM Schulte, L Marselli, F Ehehalt, D Richter, M Kleeberg, ... Diabetologia 61, 641-657, 2018 | 173 | 2018 |
The complement anaphylatoxin C5a receptor contributes to obese adipose tissue inflammation and insulin resistance J Phieler, KJ Chung, A Chatzigeorgiou, A Klotzsche-von Ameln, ... The Journal of Immunology 191 (8), 4367-4374, 2013 | 133 | 2013 |
Synergy of glucose and growth hormone signalling in islet cells through ICA512 and STAT5 H Mziaut, M Trajkovski, S Kersting, A Ehninger, A Altkrüger, RP Lemaitre, ... Nature cell biology 8 (5), 435-445, 2006 | 106 | 2006 |
Nuclear translocation of an ICA512 cytosolic fragment couples granule exocytosis and insulin expression in β-cells M Trajkovski, H Mziaut, A Altkrüger, J Ouwendijk, KP Knoch, S Müller, ... The Journal of cell biology 167 (6), 1063-1074, 2004 | 100 | 2004 |
Aged insulin granules display reduced microtubule-dependent mobility and are disposed within actin-positive multigranular bodies P Hoboth, A Müller, A Ivanova, H Mziaut, J Dehghany, A Sönmez, ... Proceedings of the National Academy of Sciences 112 (7), E667-E676, 2015 | 86 | 2015 |
The N terminus of microsomal Δ9 stearoyl-CoA desaturase contains the sequence determinant for its rapid degradation H Mziaut, G Korza, J Ozols Proceedings of the National Academy of Sciences 97 (16), 8883-8888, 2000 | 75 | 2000 |
ICA512 signaling enhances pancreatic β-cell proliferation by regulating cyclins D through STATs H Mziaut, S Kersting, KP Knoch, WH Fan, M Trajkovski, K Erdmann, ... Proceedings of the National Academy of Sciences 105 (2), 674-679, 2008 | 69 | 2008 |
MiR-132 controls pancreatic beta cell proliferation and survival through Pten/Akt/Foxo3 signaling H Mziaut, G Henniger, K Ganss, S Hempel, S Wolk, J McChord, ... Molecular metabolism 31, 150-162, 2020 | 66 | 2020 |
Targeting proteins to the lumen of endoplasmic reticulum using N-terminal domains of 11β-hydroxysteroid dehydrogenase and the 50-kDa esterase H Mziaut, G Korza, AR Hand, C Gerard, J Ozols Journal of Biological Chemistry 274 (20), 14122-14129, 1999 | 59 | 1999 |
Islet cell autoantigen of 69 kDa is an arfaptin-related protein associated with the Golgi complex of insulinoma INS-1 cells F Spitzenberger, S Pietropaolo, P Verkade, B Habermann, ... Journal of Biological Chemistry 278 (28), 26166-26173, 2003 | 49 | 2003 |
Regulation of insulin granule turnover in pancreatic β-cells by cleaved ICA512 M Trajkovski, H Mziaut, S Schubert, Y Kalaidzidis, A Altkruger, ... Journal of Biological Chemistry 283 (48), 33719-33729, 2008 | 47 | 2008 |
The F-actin modifier villin regulates insulin granule dynamics and exocytosis downstream of islet cell autoantigen 512 H Mziaut, B Mulligan, P Hoboth, O Otto, A Ivanova, M Herbig, ... Molecular metabolism 5 (8), 656-668, 2016 | 27 | 2016 |
A microsomal endopeptidase from liver that preferentially degrades stearoyl-CoA desaturase FS Heinemann, H Mziaut, G Korza, J Ozols Biochemistry 42 (23), 6929-6937, 2003 | 25 | 2003 |
A 4D view on insulin secretory granule turnover in the β‐cell A Müller, H Mziaut, M Neukam, KP Knoch, M Solimena Diabetes, Obesity and Metabolism 19, 107-114, 2017 | 22 | 2017 |
A Spatial Model of Insulin‐Granule Dynamics in Pancreatic β‐Cells J Dehghany, P Hoboth, A Ivanova, H Mziaut, A Müller, Y Kalaidzidis, ... Traffic 16 (8), 797-813, 2015 | 22 | 2015 |
Genes of type 2 diabetes in β cells M Trajkovski, H Mziaut, PE Schwarz, M Solimena Endocrinology and Metabolism Clinics 35 (2), 357-369, 2006 | 22 | 2006 |
Identification of the membrane receptor binding domain of thyroglobulin: Insights into quality control of thyroglobulin biosynthesis H Mezgrhani, H Mziaut, J Courageot, R Oughideni, P Bastiani, R Miquelis Journal of Biological Chemistry 272 (37), 23340-23346, 1997 | 22 | 1997 |
β‐Cells at the crossroads: choosing between insulin granule production and proliferation Y Liu, H Mziaut, A Ivanova, M Solimena Diabetes, Obesity and Metabolism 11, 54-64, 2009 | 18 | 2009 |
Carbohydrate and protein determinants are involved in thyroglobulin recognition by FRTL 5 cells H Mziaut, P Bastiani, T Balivet, MJ Papandreou, V Fert, K Erregragui, ... Endocrinology 137 (4), 1370-1377, 1996 | 16 | 1996 |
Molecular cloning, cDNA analysis, and localization of a monomer of the N-acetylglucosamine-specific receptor of the thyroid, NAGR1, to chromosome 19p13. 3-13.2 O Blanck, C Perrin, H Mziaut, H Darbon, MG Mattei, R Miquelis Genomics 21 (1), 18-26, 1994 | 16 | 1994 |