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David Dahlgren
David Dahlgren
Department of Pharmaceutical Biosciences, Uppsala University
Zweryfikowany adres z farmbio.uu.se
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Intestinal permeability and drug absorption: predictive experimental, computational and in vivo approaches
D Dahlgren, H Lennernäs
Pharmaceutics 11 (8), 411, 2019
2162019
Direct in vivo human intestinal permeability (Peff) determined with different clinical perfusion and intubation methods
D Dahlgren, C Roos, E Sjögren, H Lennernäs
Journal of pharmaceutical sciences 104 (9), 2702-2726, 2015
1182015
Chemotherapeutics-induced intestinal mucositis: pathophysiology and potential treatment strategies
D Dahlgren, M Sjöblom, PM Hellström, H Lennernäs
Frontiers in pharmacology 12, 681417, 2021
1102021
Regional intestinal permeability of three model drugs in human
D Dahlgren, C Roos, A Lundqvist, B Abrahamsson, C Tannergren, ...
Molecular pharmaceutics 13 (9), 3013-3021, 2016
642016
Human in Vivo Regional Intestinal Permeability: Quantitation Using Site-Specific Drug Absorption Data
E Sjogren, D Dahlgren, C Roos, H Lennernas
Molecular pharmaceutics 12 (6), 2026-2039, 2015
592015
Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability
D Dahlgren, M Venczel, JP Ridoux, C Skjöld, A Müllertz, R Holm, ...
European journal of pharmaceutics and biopharmaceutics 163, 240-251, 2021
582021
In Vivo Mechanisms of Intestinal Drug Absorption from Aprepitant Nanoformulations
C Roos, D Dahlgren, S Berg, J Westergren, B Abrahamsson, ...
Molecular Pharmaceutics 14 (12), 4233-4242, 2017
572017
Regional intestinal permeability in rats: a comparison of methods
C Roos, D Dahlgren, E Sjögren, C Tannergren, B Abrahamsson, ...
Molecular pharmaceutics 14 (12), 4252-4261, 2017
472017
The effects of three absorption-modifying critical excipients on the in vivo intestinal absorption of six model compounds in rats and dogs
D Dahlgren, C Roos, P Johansson, C Tannergren, A Lundqvist, ...
International journal of pharmaceutics, 2018
462018
Preclinical Effect of Absorption Modifying Excipients on Rat Intestinal Transport of Model Compounds and the Mucosal Barrier Marker 51Cr-EDTA
D Dahlgren, C Roos, A Lundqvist, C Tannergren, P Langguth, ...
Molecular pharmaceutics 14 (12), 4243-4251, 2017
382017
Regional intestinal permeability in dogs: Biopharmaceutical aspects for development of oral modified-release dosage forms
D Dahlgren, C Roos, P Johansson, A Lundqvist, C Tannergren, ...
Molecular Pharmaceutics 13 (9), 3022-3033, 2016
372016
Intestinal absorption-modifying excipients: A current update on preclinical in vivo evaluations
D Dahlgren, M Sjöblom, H Lennernäs
European Journal of Pharmaceutics and Biopharmaceutics 142, 411-420, 2019
352019
Effect of absorption-modifying excipients, hypotonicity, and enteric neural activity in an in vivo model for small intestinal transport
D Dahlgren, C Roos, A Lundqvist, C Tannergren, M Sjöblom, E Sjögren, ...
International journal of pharmaceutics 549 (1-2), 239-248, 2018
322018
Antibody-drug conjugates and targeted treatment strategies for hepatocellular carcinoma: a drug-delivery perspective
D Dahlgren, H Lennernäs
Molecules 25 (12), 2861, 2020
282020
Jejunal absorption of aprepitant from nanosuspensions: Role of particle size, prandial state and mucus layer
C Roos, D Dahlgren, E Sjögren, M Sjöblom, M Hedeland, H Lennernäs
European journal of pharmaceutics and biopharmaceutics 132, 222-230, 2018
272018
Evaluation of drug permeability calculation based on luminal disappearance and plasma appearance in the rat single-pass intestinal perfusion model
D Dahlgren, C Roos, K Peters, A Lundqvist, C Tannergren, E Sjögren, ...
European Journal of Pharmaceutics and Biopharmaceutics 142, 31-37, 2019
262019
Mechanistic modelling of intestinal drug absorption–The in vivo effects of nanoparticles, hydrodynamics, and colloidal structures
C Roos, J Westergren, D Dahlgren, H Lennernäs, E Sjögren
European Journal of Pharmaceutics and Biopharmaceutics 133, 70-76, 2018
262018
Time-dependent effects on small intestinal transport by absorption-modifying excipients
D Dahlgren, C Roos, A Lundqvist, C Tannergren, M Sjöblom, E Sjögren, ...
European Journal of Pharmaceutics and Biopharmaceutics 132, 19-28, 2018
232018
Effect of paracellular permeation enhancers on intestinal permeability of two peptide drugs, enalaprilat and hexarelin, in rats
D Dahlgren, T Olander, M Sjöblom, M Hedeland, H Lennernäs
Acta Pharmaceutica Sinica B 11 (6), 1667-1675, 2021
212021
The in vivo effect of transcellular permeation enhancers on the intestinal permeability of two peptide drugs enalaprilat and hexarelin
D Dahlgren, M Sjöblom, M Hedeland, H Lennernäs
Pharmaceutics 12 (2), 99, 2020
182020
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