Amorphous compositions using concentration enhancing polymers for improved bioavailability of itraconazole JC DiNunzio, DA Miller, W Yang, JW McGinity, RO Williams III Molecular pharmaceutics 5 (6), 968-980, 2008 | 223 | 2008 |
Fusion production of solid dispersions containing a heat-sensitive active ingredient by hot melt extrusion and Kinetisol® dispersing JC DiNunzio, C Brough, JR Hughey, DA Miller, RO Williams III, ... European journal of pharmaceutics and biopharmaceutics 74 (2), 340-351, 2010 | 200 | 2010 |
Enhanced in vivo absorption of itraconazole via stabilization of supersaturation following acidic-to-neutral pH transition DA Miller, JC DiNunzio, W Yang, JW McGinity, RO Williams III Drug development and industrial pharmacy 34 (8), 890-902, 2008 | 196 | 2008 |
Targeted intestinal delivery of supersaturated itraconazole for improved oral absorption DA Miller, JC DiNunzio, W Yang, JW McGinity, RO Williams Pharmaceutical research 25, 1450-1459, 2008 | 181 | 2008 |
Pharmaceutical extrusion technology I Ghebre-Sellassie, I Ghebre-Selassie, CE Martin, F Zhang, J DiNunzio, ... CRC Press, 2003 | 173 | 2003 |
Dry powder coating of pharmaceuticals: A review D Sauer, M Cerea, J DiNunzio, J McGinity International journal of pharmaceutics 457 (2), 488-502, 2013 | 108 | 2013 |
Applications of KinetiSol® Dispersing for the production of plasticizer free amorphous solid dispersions JC DiNunzio, C Brough, DA Miller, RO Williams III, JW McGinity European journal of pharmaceutical sciences 40 (3), 179-187, 2010 | 100 | 2010 |
Dissolution enhancement of a drug exhibiting thermal and acidic decomposition characteristics by fusion processing: a comparative study of hot melt extrusion and KinetiSol … JR Hughey, JC DiNunzio, RC Bennett, C Brough, DA Miller, H Ma, ... AAPs Pharmscitech 11, 760-774, 2010 | 96 | 2010 |
Melt extrusion MA Repka, N Langley, J DiNunzio Materials, Technology and Drug Product Design 4 (5), 2013 | 92 | 2013 |
Production of advanced solid dispersions for enhanced bioavailability of itraconazole using KinetiSol® Dispersing JC DiNunzio, JR Hughey, C Brough, DA Miller, RO Williams III, ... Drug development and industrial pharmacy 36 (9), 1064-1078, 2010 | 90 | 2010 |
Fusion processing of itraconazole solid dispersions by KinetiSol® dispersing: a comparative study to hot melt extrusion JC DiNunzio, C Brough, DA Miller, RO Williams III, JW McGinity Journal of pharmaceutical sciences 99 (3), 1239-1253, 2010 | 83 | 2010 |
Investigation of process temperature and screw speed on properties of a pharmaceutical solid dispersion using corotating and counter-rotating twin-screw extruders JM Keen, C Martin, A Machado, H Sandhu, JW McGinity, JC DiNunzio Journal of Pharmacy and Pharmacology 66 (2), 204-217, 2014 | 75 | 2014 |
Rheology guided rational selection of processing temperature to prepare copovidone–nifedipine amorphous solid dispersions via hot melt extrusion (HME) F Yang, Y Su, J Zhang, J DiNunzio, A Leone, C Huang, CD Brown Molecular pharmaceutics 13 (10), 3494-3505, 2016 | 68 | 2016 |
Control strategies for drug product continuous direct compression—State of control, product collection strategies, and startup/shutdown operations for the production of … A Almaya, L De Belder, R Meyer, K Nagapudi, HRH Lin, I Leavesley, ... Journal of Pharmaceutical Sciences 106 (4), 930-943, 2017 | 67 | 2017 |
Thermo-kinetic mixing for pharmaceutical applications C Brough, JW McGinity, DA Miller, J DiNunzio, RO Williams US Patent 8,486,423, 2013 | 65* | 2013 |
CNS disorders—current treatment options and the prospects for advanced therapies JC DiNunzio, RO Williams III Drug development and industrial pharmacy 34 (11), 1141-1167, 2008 | 60 | 2008 |
The impact of hot melt extrusion and spray drying on mechanical properties and tableting indices of materials used in pharmaceutical development R Iyer, S Hegde, YE Zhang, J Dinunzio, D Singhal, A Malick, G Amidon Journal of pharmaceutical sciences 102 (10), 3604-3613, 2013 | 56 | 2013 |
Use of highly compressible Ceolus™ microcrystalline cellulose for improved dosage form properties containing a hydrophilic solid dispersion JC DiNunzio, SU Schilling, AW Coney, JR Hughey, N Kaneko, ... Drug Development and Industrial Pharmacy 38 (2), 180-189, 2012 | 52 | 2012 |
Melt extrusion JC DiNunzio, F Zhang, C Martin, JW McGinity Formulating poorly water soluble drugs, 311-362, 2011 | 48 | 2011 |
Flocculated amorphous itraconazole nanoparticles for enhanced in vitro supersaturation and in vivo bioavailability MA Miller, J DiNunzio, ME Matteucci, BS Ludher, RO Williams, ... Drug development and industrial pharmacy 38 (5), 557-570, 2012 | 47 | 2012 |