Non-invasive intravital imaging of cellular differentiation with a bright red-excitable fluorescent protein J Chu, RD Haynes, SY Corbel, P Li, E González-González, JS Burg, ... Nature methods 11 (5), 572-578, 2014 | 273 | 2014 |
In Vivo Sustained Release of siRNA from Solid Lipid Nanoparticles T Lobovkina, GB Jacobson, E Gonzalez-Gonzalez, RP Hickerson, ... ACS nano 5 (12), 9977-9983, 2011 | 161 | 2011 |
Stability study of unmodified siRNA and relevance to clinical use RP Hickerson, AV Vlassov, Q Wang, D Leake, H Ilves, ... Oligonucleotides 18 (4), 345-354, 2008 | 161 | 2008 |
Gene silencing following siRNA delivery to skin via coated steel microneedles: In vitro and in vivo proof-of-concept RHE Chong, E Gonzalez-Gonzalez, MF Lara, TJ Speaker, CH Contag, ... Journal of Controlled Release 166 (3), 211-219, 2013 | 130 | 2013 |
Silencing of reporter gene expression in skin using siRNAs and expression of plasmid DNA delivered by a soluble protrusion array device (PAD) E Gonzalez-Gonzalez, TJ Speaker, RP Hickerson, R Spitler, MA Flores, ... Molecular Therapy 18 (9), 1667-1674, 2010 | 91 | 2010 |
The expression patterns of genes involved in the RNAi pathways are tissue-dependent and differ in the germ and somatic cells of mouse testis E González-González, PP López-Casas, J Del Mazo Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1779 (5), 306-311, 2008 | 80 | 2008 |
Biodegradable nanoparticles with sustained release of functional siRNA in skin GB Jacobson, E Gonzalez‐Gonzalez, R Spitler, R Shinde, D Leake, ... Journal of pharmaceutical sciences 99 (10), 4261-4266, 2010 | 63 | 2010 |
Inhibition of CD44 gene expression in human skin models, using self-delivery short interfering RNA administered by dissolvable microneedle arrays MF Lara, E González-González, TJ Speaker, RP Hickerson, D Leake, ... Human gene therapy 23 (8), 816-823, 2012 | 59 | 2012 |
One gene determines maize B chromosome accumulation by preferential fertilisation; another gene (s) determines their meiotic loss M González-Sánchez, E González-González, F Molina, AM Chiavarino, ... Heredity 90 (2), 122-129, 2003 | 54 | 2003 |
siRNA silencing of keratinocyte-specific GFP expression in a transgenic mouse skin model E Gonzalez-Gonzalez, H Ra, RP Hickerson, Q Wang, ... Gene therapy 16 (8), 963-972, 2009 | 52 | 2009 |
Generic and personalized RNAi-based therapeutics for a dominant-negative epidermal fragility disorder DML Pedrioli, DJ Fu, E Gonzalez-Gonzalez, CH Contag, RL Kaspar, ... Journal of investigative dermatology 132 (6), 1627-1635, 2012 | 45 | 2012 |
In vivo imaging of human and mouse skin with a handheld dual-axis confocal fluorescence microscope H Ra, W Piyawattanametha, E Gonzalez-Gonzalez, MJ Mandella, ... Journal of investigative dermatology 131 (5), 1061-1066, 2011 | 38 | 2011 |
Detection of non-melanoma skin cancer by in vivo fluorescence imaging with fluorocoxib A H Ra, E González-González, MJ Uddin, BL King, A Lee, I Ali-Khan, ... Neoplasia 17 (2), 201-207, 2015 | 35 | 2015 |
Gene silencing in skin after deposition of self-delivery siRNA with a motorized microneedle array device RP Hickerson, WC Wey, DL Rimm, T Speaker, S Suh, MA Flores, ... Molecular Therapy Nucleic Acids 2, 2013 | 31 | 2013 |
Development of quantitative molecular clinical end points for siRNA clinical trials RP Hickerson, SA Leachman, LN Pho, E Gonzalez-Gonzalez, FJD Smith, ... Journal of Investigative Dermatology 131 (5), 1029-1036, 2011 | 30 | 2011 |
Gene silencing by RNAi in mouse Sertoli cells E González-González, PP López-Casas, J Del Mazo Reproductive Biology and Endocrinology 6, 1-9, 2008 | 30 | 2008 |
Visualization of plasmid delivery to keratinocytes in mouse and human epidermis E González-González, YC Kim, TJ Speaker, RP Hickerson, R Spitler, ... Scientific reports 1 (1), 158, 2011 | 28 | 2011 |
Increased interstitial pressure improves nucleic acid delivery to skin enabling a comparative analysis of constitutive promoters E González-González, H Ra, R Spitler, RP Hickerson, CH Contag, ... Gene therapy 17 (10), 1270-1278, 2010 | 18 | 2010 |
Assessing delivery and quantifying efficacy of small interfering ribonucleic acid therapeutics in the skin using a dual-axis confocal microscope H Ra, E Gonzalez-Gonzalez, BR Smith, SS Gambhir, GS Kino, ... Journal of Biomedical Optics 15 (3), 036027-036027-5, 2010 | 16 | 2010 |
Gene silencing following siRNA delivery to skin via coated steel microneedles RH Chong, E Gonzalez-Gonzalez, MF Lara, TJ Speaker, CH Contag, ... vitro, 2013 | 15 | 2013 |