The genetic evolution of melanoma from precursor lesions AH Shain, I Yeh, I Kovalyshyn, A Sriharan, E Talevich, A Gagnon, ... New England Journal of Medicine 373 (20), 1926-1936, 2015 | 1164 | 2015 |
Kinase fusions are frequent in Spitz tumours and spitzoid melanomas T Wiesner, J He, R Yelensky, R Esteve-Puig, T Botton, I Yeh, D Lipson, ... Nature communications 5 (1), 3116, 2014 | 641 | 2014 |
Computational analysis of Plasmodium falciparum metabolism: organizing genomic information to facilitate drug discovery I Yeh, T Hanekamp, S Tsoka, PD Karp, RB Altman Genome research 14 (5), 917-924, 2004 | 294 | 2004 |
Whole-genome landscape of mucosal melanoma reveals diverse drivers and therapeutic targets F Newell, Y Kong, JS Wilmott, PA Johansson, PM Ferguson, C Cui, Z Li, ... Nature communications 10 (1), 3163, 2019 | 283 | 2019 |
UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling C Moore, F Cevikbas, HA Pasolli, Y Chen, W Kong, C Kempkes, P Parekh, ... Proceedings of the National Academy of Sciences 110 (34), E3225-E3234, 2013 | 274 | 2013 |
Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway AH Shain, M Garrido, T Botton, E Talevich, I Yeh, JZ Sanborn, J Chung, ... Nature genetics 47 (10), 1194-1199, 2015 | 273 | 2015 |
Activating MET kinase rearrangements in melanoma and Spitz tumours I Yeh, T Botton, E Talevich, AH Shain, AJ Sparatta, A De La Fouchardiere, ... Nature communications 6 (1), 7174, 2015 | 252 | 2015 |
Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy CN Kline, NM Joseph, JP Grenert, J van Ziffle, E Talevich, C Onodera, ... Neuro-oncology 19 (5), 699-709, 2017 | 248 | 2017 |
Modelling biological processes using workflow and petri net models M Peleg, I Yeh, RB Altman Bioinformatics 18 (6), 825-837, 2002 | 218 | 2002 |
Knowledge acquisition, consistency checking and concurrency control for Gene Ontology (GO) I Yeh, PD Karp, NF Noy, RB Altman Bioinformatics 19 (2), 241-248, 2003 | 213 | 2003 |
Genomic and transcriptomic analysis reveals incremental disruption of key signaling pathways during melanoma evolution AH Shain, NM Joseph, R Yu, J Benhamida, S Liu, T Prow, B Ruben, ... Cancer cell 34 (1), 45-55. e4, 2018 | 212 | 2018 |
Clinical, histopathologic, and genomic features of Spitz tumors with ALK fusions I Yeh, A de la Fouchardiere, D Pissaloux, TW Mully, MC Garrido, ... The American journal of surgical pathology 39 (5), 581-591, 2015 | 186 | 2015 |
Targeted genomic profiling of acral melanoma I Yeh, E Jorgenson, L Shen, M Xu, JP North, AH Shain, D Reuss, H Wu, ... JNCI: Journal of the National Cancer Institute 111 (10), 1068-1077, 2019 | 170 | 2019 |
Melanoma models for the next generation of therapies EE Patton, KL Mueller, DJ Adams, N Anandasabapathy, AE Aplin, ... Cancer cell 39 (5), 610-631, 2021 | 163 | 2021 |
NTRK3 kinase fusions in Spitz tumours I Yeh, MK Tee, T Botton, AH Shain, AJ Sparatta, A Gagnon, SS Vemula, ... The Journal of pathology 240 (3), 282-290, 2016 | 156 | 2016 |
Human tumor genomics and zebrafish modeling identify SPRED1 loss as a driver of mucosal melanoma J Ablain, M Xu, H Rothschild, RC Jordan, JK Mito, BH Daniels, CF Bell, ... Science 362 (6418), 1055-1060, 2018 | 149 | 2018 |
Recurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapy T Botton, I Yeh, T Nelson, SS Vemula, A Sparatta, MC Garrido, M Allegra, ... Pigment cell & melanoma research 26 (6), 845-851, 2013 | 139 | 2013 |
Bi-allelic loss of CDKN2A initiates melanoma invasion via BRN2 activation H Zeng, A Jorapur, AH Shain, UE Lang, R Torres, Y Zhang, AS McNeal, ... Cancer cell 34 (1), 56-68. e9, 2018 | 136 | 2018 |
Combined activation of MAP kinase pathway and β-catenin signaling cause deep penetrating nevi I Yeh, UE Lang, E Durieux, MK Tee, A Jorapur, AH Shain, V Haddad, ... Nature communications 8 (1), 644, 2017 | 135 | 2017 |
Cross-species genomic landscape comparison of human mucosal melanoma with canine oral and equine melanoma K Wong, L van der Weyden, CR Schott, A Foote, F Constantino-Casas, ... Nature communications 10 (1), 353, 2019 | 133 | 2019 |