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Jacques Pouyssegur
Jacques Pouyssegur
IRCAN, Centre A. Lacassagne, University of Nice and Centre Scientifique de Monaco (CSM)
Zweryfikowany adres z unice.fr - Strona główna
Tytuł
Cytowane przez
Cytowane przez
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Tumor cell metabolism: cancer's Achilles' heel
G Kroemer, J Pouyssegur
Cancer cell 13 (6), 472-482, 2008
28252008
Hypoxia signalling in cancer and approaches to enforce tumour regression
J Pouysségur, F Dayan, NM Mazure
Nature 441 (7092), 437-443, 2006
21282006
HIF prolyl‐hydroxylase 2 is the key oxygen sensor setting low steady‐state levels of HIF‐1α in normoxia
E Berra, E Benizri, A Ginouvès, V Volmat, D Roux, J Pouysségur
The EMBO journal, 2003
17752003
Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains
G Bellot, R Garcia-Medina, P Gounon, J Chiche, D Roux, J Pouysségur, ...
Molecular and cellular biology 29 (10), 2570-2581, 2009
16992009
Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway
JN Lavoie, G L'Allemain, A Brunet, R Müller, J Pouysségur
Journal of Biological Chemistry 271 (34), 20608-20616, 1996
16321996
LDHA-associated lactic acid production blunts tumor immunosurveillance by T and NK cells
A Brand, K Singer, GE Koehl, M Kolitzus, G Schoenhammer, A Thiel, ...
Cell metabolism 24 (5), 657-671, 2016
15712016
The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1-to S-phase transition
S Meloche, J Pouysségur
Oncogene 26 (22), 3227-3239, 2007
14092007
Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation.
G Pagès, P Lenormand, G L'Allemain, JC Chambard, S Meloche, ...
Proceedings of the National Academy of Sciences 90 (18), 8319-8323, 1993
12971993
p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1α (HIF-1α) and enhance the transcriptional activity of HIF-1
DE Richard, E Berra, E Gothié, D Roux, J Pouysségur
Journal of Biological Chemistry 274 (46), 32631-32637, 1999
10611999
Hypoxia and cancer
MC Brahimi-Horn, J Chiche, J Pouysségur
Journal of molecular medicine 85, 1301-1307, 2007
10022007
ERK implication in cell cycle regulation
JC Chambard, R Lefloch, J Pouysségur, P Lenormand
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1773 (8), 1299-1310, 2007
9832007
Molecular cloning, primary structure, and expression of the human growth factor-activatable Na+ H+ antiporter
C Sardet, A Franchi, J Pouysségur
Cell 56 (2), 271-280, 1989
9811989
Prolyl hydroxylase-1 negatively regulates IκB kinase-β, giving insight into hypoxia-induced NFκB activity
EP Cummins, E Berra, KM Comerford, A Ginouves, KT Fitzgerald, ...
Proceedings of the National Academy of Sciences 103 (48), 18154-18159, 2006
9362006
Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice
G Pagès, S Guérin, D Grall, F Bonino, A Smith, F Anjuere, P Auberger, ...
Science 286 (5443), 1374-1377, 1999
9101999
Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH
J Chiche, K Ilc, J Laferriere, E Trottier, F Dayan, NM Mazure, ...
Cancer research 69 (1), 358-368, 2009
8782009
Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1α in vascular smooth muscle cells
DE Richard, E Berra, J Pouysségur
Journal of Biological Chemistry 275 (35), 26765-26771, 2000
8762000
Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts
P Lenormand, C Sardet, G L'Allemain, A Brunet, J Pouyssegur
Journal of Cell Biology 122 (5), 1079-1088, 1993
8631993
Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer
J Chiche, MC Brahimi‐Horn, J Pouysségur
Journal of cellular and molecular medicine 14 (4), 771-794, 2010
8202010
Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling
J Pouysségur, V Volmat, P Lenormand
Biochemical pharmacology 64 (5-6), 755-763, 2002
790*2002
Nuclear translocation of p42/p44 mitogen‐activated protein kinase is required for growth factor‐induced gene expression and cell cycle entry
A Brunet, DL Roux, P Lenormand, S Dowd, S Keyse, J Pouysségur
The EMBO journal, 1999
7691999
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